Click here to switch to the map view.

The map label for this gene is epsC [H]

Identifier: 37678397

GI number: 37678397

Start: 224220

End: 225149

Strand: Direct

Name: epsC [H]

Synonym: VV0213

Alternate gene names: 37678397

Gene position: 224220-225149 (Clockwise)

Preceding gene: 37678396

Following gene: 37678398

Centisome position: 6.68

GC content: 50.54

Gene sequence:

>930_bases
GTGAAACCATCAGAGCTGAGTGCCGGATTGGCCAATAGCCCATTGCTGACGCGGATGATTGCCAACAACGGCATGATTCA
GAGTCGAGCGAGTGCTTTATTAGCTGGCGTGCTGGTGGCTTTGACAGGCTGGACTTTAGGGCAAGTCGTCTGGCTAACAC
AAGAGAGCAATACGCAGATCGTCGCTTGGCGACCTGCACCGCAGCAAAACGCACAAGGTAAACAAGGTGAGCGATTAAAC
CTCGCCGATCTGCAAGCCATCAATTTGTTTGGAGTTTACAACGAGAACAAACCTAAGCCTGTTGTCAGCCAGCCGGTGGT
GCAAGACGCGCCTAAAACGCGGCTAAATTTGGTGCTAGTTGGGGCAGTGGCGAGCAGCAATCCTCAAACCAGCTTGGCCG
TTATCGCCAACCGTGGTCAGCAAGCGACCTACGGGGTTGGGGAAGAAATCGAAGGCACTCGCGCTAAGTTAAAAGCGGTT
CTGGTCGATCGTGTGATCATCGATAATGAAGGGCGTGACGAGACCCTGATGCTTGAAGGCGTGGAATACAAGAAATTGTC
TGAATCTGCTCCGCGTGTCATTCCGTCATCGACGATCGCTAAGAATAACCCGCCAGATACAGATGAGCAGCTAGCGCAAA
TTCGAGAAGAAATTACCGCCGATCCGCAGAAGATTTTCCAATACGTGCGTTTGTCTCAAGTGAAGCAAGAAGACAAAGTG
ATTGGTTATCGCGTGAGTCCGGGAAAAAGCCCACAACTGTTTGAAGCCGTTGGGTTACAAGATGGGGATATTGCTGTGCA
GTTAAATGGCAATGATCTCACCGACCCAGCCGCCATGGGCAAAATTTTTAATGCTGTTTCAGAGCTCACCGAGTTGAACC
TCACGGTGGAACGAGACGGACAGCAGCATGATATTTACATCCAGTTTTAA

Upstream 100 bases:

>100_bases
CGAGCGATTATCTTCAGTCGAATAAAGAAAGATAAATCGCAGTGCGTTCAAGCAAAGAAAGCGAAAGCGCAAAATTTAAA
CAGTGAAAGGAACCGATTGA

Downstream 100 bases:

>100_bases
CACTTAGGCTCAAAGCGTAAGTTCAGGGAGATAAACGTGAAACATTGGTTTAGCAAAAGCGCTTGGCTACTCGCAGGTAC
CTTAGCCTGCTCAAGCGGCG

Product: type II secretory pathway, component EpsC

Products: NA

Alternate protein names: Cholera toxin secretion protein epsC [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKPSELSAGLANSPLLTRMIANNGMIQSRASALLAGVLVALTGWTLGQVVWLTQESNTQIVAWRPAPQQNAQGKQGERLN
LADLQAINLFGVYNENKPKPVVSQPVVQDAPKTRLNLVLVGAVASSNPQTSLAVIANRGQQATYGVGEEIEGTRAKLKAV
LVDRVIIDNEGRDETLMLEGVEYKKLSESAPRVIPSSTIAKNNPPDTDEQLAQIREEITADPQKIFQYVRLSQVKQEDKV
IGYRVSPGKSPQLFEAVGLQDGDIAVQLNGNDLTDPAAMGKIFNAVSELTELNLTVERDGQQHDIYIQF

Sequences:

>Translated_309_residues
MKPSELSAGLANSPLLTRMIANNGMIQSRASALLAGVLVALTGWTLGQVVWLTQESNTQIVAWRPAPQQNAQGKQGERLN
LADLQAINLFGVYNENKPKPVVSQPVVQDAPKTRLNLVLVGAVASSNPQTSLAVIANRGQQATYGVGEEIEGTRAKLKAV
LVDRVIIDNEGRDETLMLEGVEYKKLSESAPRVIPSSTIAKNNPPDTDEQLAQIREEITADPQKIFQYVRLSQVKQEDKV
IGYRVSPGKSPQLFEAVGLQDGDIAVQLNGNDLTDPAAMGKIFNAVSELTELNLTVERDGQQHDIYIQF
>Mature_309_residues
MKPSELSAGLANSPLLTRMIANNGMIQSRASALLAGVLVALTGWTLGQVVWLTQESNTQIVAWRPAPQQNAQGKQGERLN
LADLQAINLFGVYNENKPKPVVSQPVVQDAPKTRLNLVLVGAVASSNPQTSLAVIANRGQQATYGVGEEIEGTRAKLKAV
LVDRVIIDNEGRDETLMLEGVEYKKLSESAPRVIPSSTIAKNNPPDTDEQLAQIREEITADPQKIFQYVRLSQVKQEDKV
IGYRVSPGKSPQLFEAVGLQDGDIAVQLNGNDLTDPAAMGKIFNAVSELTELNLTVERDGQQHDIYIQF

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3031

COG function: function code U; Type II secretory pathway, component PulC

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001639 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33589; Mature: 33589

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSELSAGLANSPLLTRMIANNGMIQSRASALLAGVLVALTGWTLGQVVWLTQESNTQI
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
VAWRPAPQQNAQGKQGERLNLADLQAINLFGVYNENKPKPVVSQPVVQDAPKTRLNLVLV
EEECCCCCCCCCCCCCCCCCHHHEEEEEEEEEECCCCCCCCCCCCHHHCCCCCEEEEEEE
GAVASSNPQTSLAVIANRGQQATYGVGEEIEGTRAKLKAVLVDRVIIDNEGRDETLMLEG
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCEEEEEC
VEYKKLSESAPRVIPSSTIAKNNPPDTDEQLAQIREEITADPQKIFQYVRLSQVKQEDKV
CCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCE
IGYRVSPGKSPQLFEAVGLQDGDIAVQLNGNDLTDPAAMGKIFNAVSELTELNLTVERDG
EEEEECCCCCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCC
QQHDIYIQF
CCCEEEEEC
>Mature Secondary Structure
MKPSELSAGLANSPLLTRMIANNGMIQSRASALLAGVLVALTGWTLGQVVWLTQESNTQI
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
VAWRPAPQQNAQGKQGERLNLADLQAINLFGVYNENKPKPVVSQPVVQDAPKTRLNLVLV
EEECCCCCCCCCCCCCCCCCHHHEEEEEEEEEECCCCCCCCCCCCHHHCCCCCEEEEEEE
GAVASSNPQTSLAVIANRGQQATYGVGEEIEGTRAKLKAVLVDRVIIDNEGRDETLMLEG
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCEEEEEC
VEYKKLSESAPRVIPSSTIAKNNPPDTDEQLAQIREEITADPQKIFQYVRLSQVKQEDKV
CCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCE
IGYRVSPGKSPQLFEAVGLQDGDIAVQLNGNDLTDPAAMGKIFNAVSELTELNLTVERDG
EEEEECCCCCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCC
QQHDIYIQF
CCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]