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The map label for this gene is degP [H]

Identifier: 37523310

GI number: 37523310

Start: 3952562

End: 3953485

Strand: Direct

Name: degP [H]

Synonym: glr3741

Alternate gene names: 37523310

Gene position: 3952562-3953485 (Clockwise)

Preceding gene: 37523308

Following gene: 37523311

Centisome position: 84.84

GC content: 69.81

Gene sequence:

>924_bases
ATGACTTCACCGACAGGTGCTTTGCTAGCTTTTTCCAACGCCCTGGCTGATACCGTCGAAGCGGCCGGCCGGGCGGTGGT
CGCCGTCGACACCCACGCGCGCAGCACGCCCAGCGGCGTGCTCTGGCGCGAAGGGGTTGTCGTCACCGCCGACCACCTGC
TCAAGCGCGACGACGAAATAACGGTCACTTTGCACGATGGGCGCACGGTGGCAGCAACGCTGGCCGGGCGCGATCCCGGC
ACCGATCTGGCGGTGTTGCGCTTGGCGGACGCCCCCGCCCCCGAGGTGCCCTTTGGCGATGCCCAACTGCTCAAAGTCGG
GCATCTGGCTCTCGCCCTCGCCCGCCCGGGCGAGCACGGCCTGAGTGCCAGCCTCGGCACCGTCTGCAACGTGGGCGGTC
CCTGGCGCACCTGGCGCGGCGGACAGATCGACCGGCTCATCCGCCTGGATCTGAGCTTGTTTCCGGGATTTTCCGGCGGC
GCCCTGGTGGACACCGAAGGCCGCATCGTCGGGATCAACACCGCCGCGCTCTCGCGCAGCACCGGGATCGCCATTCCGGC
CGCCACCGTCGATCGGGTGGTGGACCAGCTGCTGGCCACCGGGCGGGTCGCCCGCGGCTATCTGGGCATCGGCATGCAGC
CGGTGCGCCTGCCCGACAGCCTGCGCGCCACCCTCAATTTGCCCGGTACGGGTGCGGTGATCGTCGTCAACCTCGAAGCG
GACGCCCCCGCCGAGCGCGCCGGTGTGCTGCTGGGCGATGTATTCATCGGGATCGACGGCCACACCGTCGGGGACACCGA
GGAGGTGCTGGCCCTGTTGACCCCCGAGCGGGTCGGCAAGAGCGTACCGGTGCAGATCGTCCGGGGCGGTCAGCTGGTCG
AGGTGTCCGTCACTGTCGGCGAACGGCTGCGGAGAGGGACGTGA

Upstream 100 bases:

>100_bases
GCCGCTAGCCGATCCGCCGATGGTATCCGTCTCCACGGTACGACAAGCTTGAAGTACAGGACAGCCACCAGCCTGTCTCA
CTCGCATTGCGGAGCCCACC

Downstream 100 bases:

>100_bases
ATACCCGGCACCCAGAGCAAGCAGAAAGTCTGGAGGCGGCAGGATTTTGGATCGCCTGCGGGCGGAGTGCGGCATGATTC
GGGTGGCGGTGGCGGCCGAT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTSPTGALLAFSNALADTVEAAGRAVVAVDTHARSTPSGVLWREGVVVTADHLLKRDDEITVTLHDGRTVAATLAGRDPG
TDLAVLRLADAPAPEVPFGDAQLLKVGHLALALARPGEHGLSASLGTVCNVGGPWRTWRGGQIDRLIRLDLSLFPGFSGG
ALVDTEGRIVGINTAALSRSTGIAIPAATVDRVVDQLLATGRVARGYLGIGMQPVRLPDSLRATLNLPGTGAVIVVNLEA
DAPAERAGVLLGDVFIGIDGHTVGDTEEVLALLTPERVGKSVPVQIVRGGQLVEVSVTVGERLRRGT

Sequences:

>Translated_307_residues
MTSPTGALLAFSNALADTVEAAGRAVVAVDTHARSTPSGVLWREGVVVTADHLLKRDDEITVTLHDGRTVAATLAGRDPG
TDLAVLRLADAPAPEVPFGDAQLLKVGHLALALARPGEHGLSASLGTVCNVGGPWRTWRGGQIDRLIRLDLSLFPGFSGG
ALVDTEGRIVGINTAALSRSTGIAIPAATVDRVVDQLLATGRVARGYLGIGMQPVRLPDSLRATLNLPGTGAVIVVNLEA
DAPAERAGVLLGDVFIGIDGHTVGDTEEVLALLTPERVGKSVPVQIVRGGQLVEVSVTVGERLRRGT
>Mature_306_residues
TSPTGALLAFSNALADTVEAAGRAVVAVDTHARSTPSGVLWREGVVVTADHLLKRDDEITVTLHDGRTVAATLAGRDPGT
DLAVLRLADAPAPEVPFGDAQLLKVGHLALALARPGEHGLSASLGTVCNVGGPWRTWRGGQIDRLIRLDLSLFPGFSGGA
LVDTEGRIVGINTAALSRSTGIAIPAATVDRVVDQLLATGRVARGYLGIGMQPVRLPDSLRATLNLPGTGAVIVVNLEAD
APAERAGVLLGDVFIGIDGHTVGDTEEVLALLTPERVGKSVPVQIVRGGQLVEVSVTVGERLRRGT

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI7019477, Length=315, Percent_Identity=29.2063492063492, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4506141, Length=293, Percent_Identity=27.3037542662116, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI22129776, Length=285, Percent_Identity=24.5614035087719, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI24308541, Length=304, Percent_Identity=24.0131578947368, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1789630, Length=283, Percent_Identity=31.095406360424, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789629, Length=270, Percent_Identity=29.2592592592593, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786356, Length=264, Percent_Identity=27.6515151515151, Blast_Score=101, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24646839, Length=318, Percent_Identity=24.8427672955975, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 31724; Mature: 31593

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTGALLAFSNALADTVEAAGRAVVAVDTHARSTPSGVLWREGVVVTADHLLKRDDEI
CCCCCCHHEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCEEEEEHHHHCCCCEE
TVTLHDGRTVAATLAGRDPGTDLAVLRLADAPAPEVPFGDAQLLKVGHLALALARPGEHG
EEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHEEEEEECCCCCC
LSASLGTVCNVGGPWRTWRGGQIDRLIRLDLSLFPGFSGGALVDTEGRIVGINTAALSRS
CCCCCCCEECCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCEEEECCCEEEEEEHHHCCCC
TGIAIPAATVDRVVDQLLATGRVARGYLGIGMQPVRLPDSLRATLNLPGTGAVIVVNLEA
CCCEECHHHHHHHHHHHHHCCCHHCCEECCCCCCEECCCCCEEEEECCCCCEEEEEEECC
DAPAERAGVLLGDVFIGIDGHTVGDTEEVLALLTPERVGKSVPVQIVRGGQLVEVSVTVG
CCCHHHCCEEEEEEEEEECCCCCCCHHHHHEEECHHHHCCCCCEEEEECCEEEEEEEEHH
ERLRRGT
HHHHCCC
>Mature Secondary Structure 
TSPTGALLAFSNALADTVEAAGRAVVAVDTHARSTPSGVLWREGVVVTADHLLKRDDEI
CCCCCHHEEHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCEEEEEHHHHCCCCEE
TVTLHDGRTVAATLAGRDPGTDLAVLRLADAPAPEVPFGDAQLLKVGHLALALARPGEHG
EEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHEEEEEECCCCCC
LSASLGTVCNVGGPWRTWRGGQIDRLIRLDLSLFPGFSGGALVDTEGRIVGINTAALSRS
CCCCCCCEECCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCEEEECCCEEEEEEHHHCCCC
TGIAIPAATVDRVVDQLLATGRVARGYLGIGMQPVRLPDSLRATLNLPGTGAVIVVNLEA
CCCEECHHHHHHHHHHHHHCCCHHCCEECCCCCCEECCCCCEEEEECCCCCEEEEEEECC
DAPAERAGVLLGDVFIGIDGHTVGDTEEVLALLTPERVGKSVPVQIVRGGQLVEVSVTVG
CCCHHHCCEEEEEEEEEECCCCCCCHHHHHEEECHHHHCCCCCEEEEECCEEEEEEEEHH
ERLRRGT
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]