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The map label for this gene is grsT [H]

Identifier: 37522419

GI number: 37522419

Start: 3040687

End: 3041460

Strand: Direct

Name: grsT [H]

Synonym: glr2850

Alternate gene names: 37522419

Gene position: 3040687-3041460 (Clockwise)

Preceding gene: 37522418

Following gene: 37522420

Centisome position: 65.26

GC content: 63.18

Gene sequence:

>774_bases
ATGAACAGGCATTCCCTTGCTGCGCGCGAGGAGGGCAAGCCGCGCCTGCGACTATTTTGCTTGCCCTACGCCGGGGGCGG
AACCTCGGTGTACAGCACCTGGAACAGGCGCCTGCCGCCGGAGGTGCAAGTGTGCACACTCCCGTTTCCCGGCCGCGAAC
AACTGTGGCAGGAGGCTTTGCTCGATCGCTTCGAAGCGCTCATCGAACGGCTGGTCGGGGCGCTCGAAGGCAGGCTCGAC
CAGCCCTACGCCCTGTTCGGCCACAGCCTCGGAGCGTTGGTGGCCTTCGAACTGGCCCGCCGCCTCCGGCAGTTGTACGG
GACCAACCCCGTCTGTCTATTCGTTTCGGGGCGCCAGGCGCCGCACCTCGCCGATCGGCTCCCCCCGCTCCACGCGCTGC
CTGCCGGAGAATTTGTCGAGCAACTGCGCCGCCGTTACAACGGCATCCCCCAAGCCATTTTCGAGAACCCTGAGTGGCTG
CGGTTTTTTCTGCCCGTGCTGCGGGCTGATATAGCCCTGCTTGAGACCTACGAGTATACGGGCGAGCGGCCCTTCACCTG
TCCCATCTGCGTCTTCGGCGGCCTTAAGGACAGTCTCATCGGCATCGAAGCGTTAGAAGCCTGGCGCGTCCACACGGTTG
GCGCCTTCCAATTGCAGCTGTATCCCGGCGATCACTTTTTTATCCATGACGACAAACTGCCGCTGGTTGCGGTGATCGCC
GCACAATTGCACAGCGAAGGTTGGATCCAAGGAGGGGCCCATGCCGGAGTATGA

Upstream 100 bases:

>100_bases
ACGTGCCCATCAATTTGTTGTTCAACCTCACCAGCTGTGCGCAACTGGCAACTCTGGTGCAGGATGCGCTCGCTGAACAT
GCTGTGGTGGAAACAAAACG

Downstream 100 bases:

>100_bases
CCGCAGCCTGTGGCGTCCGGCCCCCAGACAACCCGGTCTGGGCGCAGACGACGTGCACGTCTGGCGCGCCTGTCTGATGC
AGCCGGACGCGCGCGTGCTG

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNRHSLAAREEGKPRLRLFCLPYAGGGTSVYSTWNRRLPPEVQVCTLPFPGREQLWQEALLDRFEALIERLVGALEGRLD
QPYALFGHSLGALVAFELARRLRQLYGTNPVCLFVSGRQAPHLADRLPPLHALPAGEFVEQLRRRYNGIPQAIFENPEWL
RFFLPVLRADIALLETYEYTGERPFTCPICVFGGLKDSLIGIEALEAWRVHTVGAFQLQLYPGDHFFIHDDKLPLVAVIA
AQLHSEGWIQGGAHAGV

Sequences:

>Translated_257_residues
MNRHSLAAREEGKPRLRLFCLPYAGGGTSVYSTWNRRLPPEVQVCTLPFPGREQLWQEALLDRFEALIERLVGALEGRLD
QPYALFGHSLGALVAFELARRLRQLYGTNPVCLFVSGRQAPHLADRLPPLHALPAGEFVEQLRRRYNGIPQAIFENPEWL
RFFLPVLRADIALLETYEYTGERPFTCPICVFGGLKDSLIGIEALEAWRVHTVGAFQLQLYPGDHFFIHDDKLPLVAVIA
AQLHSEGWIQGGAHAGV
>Mature_257_residues
MNRHSLAAREEGKPRLRLFCLPYAGGGTSVYSTWNRRLPPEVQVCTLPFPGREQLWQEALLDRFEALIERLVGALEGRLD
QPYALFGHSLGALVAFELARRLRQLYGTNPVCLFVSGRQAPHLADRLPPLHALPAGEFVEQLRRRYNGIPQAIFENPEWL
RFFLPVLRADIALLETYEYTGERPFTCPICVFGGLKDSLIGIEALEAWRVHTVGAFQLQLYPGDHFFIHDDKLPLVAVIA
AQLHSEGWIQGGAHAGV

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=220, Percent_Identity=28.6363636363636, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI8922871, Length=190, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28918; Mature: 28918

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRHSLAAREEGKPRLRLFCLPYAGGGTSVYSTWNRRLPPEVQVCTLPFPGREQLWQEAL
CCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHH
LDRFEALIERLVGALEGRLDQPYALFGHSLGALVAFELARRLRQLYGTNPVCLFVSGRQA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
PHLADRLPPLHALPAGEFVEQLRRRYNGIPQAIFENPEWLRFFLPVLRADIALLETYEYT
CCHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
GERPFTCPICVFGGLKDSLIGIEALEAWRVHTVGAFQLQLYPGDHFFIHDDKLPLVAVIA
CCCCCCCHHEEECCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCEEEEECCCCHHHHHHH
AQLHSEGWIQGGAHAGV
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNRHSLAAREEGKPRLRLFCLPYAGGGTSVYSTWNRRLPPEVQVCTLPFPGREQLWQEAL
CCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHH
LDRFEALIERLVGALEGRLDQPYALFGHSLGALVAFELARRLRQLYGTNPVCLFVSGRQA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
PHLADRLPPLHALPAGEFVEQLRRRYNGIPQAIFENPEWLRFFLPVLRADIALLETYEYT
CCHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
GERPFTCPICVFGGLKDSLIGIEALEAWRVHTVGAFQLQLYPGDHFFIHDDKLPLVAVIA
CCCCCCCHHEEECCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCEEEEECCCCHHHHHHH
AQLHSEGWIQGGAHAGV
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]