Click here to switch to the map view.

The map label for this gene is hetI [H]

Identifier: 37522420

GI number: 37522420

Start: 3041447

End: 3042253

Strand: Direct

Name: hetI [H]

Synonym: glr2851

Alternate gene names: 37522420

Gene position: 3041447-3042253 (Clockwise)

Preceding gene: 37522419

Following gene: 37522428

Centisome position: 65.28

GC content: 62.58

Gene sequence:

>807_bases
ATGCCGGAGTATGACCGCAGCCTGTGGCGTCCGGCCCCCAGACAACCCGGTCTGGGCGCAGACGACGTGCACGTCTGGCG
CGCCTGTCTGATGCAGCCGGACGCGCGCGTGCTGGAACTGGTCGAAACGCTCTCCGAGGACGAGCGCCACCGCGCCGAGC
GCTACCGCTTTGTGGGGGATAAAAGGCGCTTTATCGTCGCTCGGGGGCTGTTGCGCCGGATCCTCCGTTGCTACCTGGAG
ATCCCCGCCGCTCAGATCCGCTTCAGCTATGGCATCAAGGGCAAACCGGCTCTGGCTTTGCCCGGGTGTACCCTGCAATT
CAACCTCTCCCATTCGCGGGAAGTGGTGCTGATCGCCCTCACCCTGCGCCGGGATATCGGCATCGATCTCGAGCTGGTGC
GTTCTTTAGCAGCAATGGATCAGATGGCCGAGCGGTTCTTCTCCGCCCACGAGAAGCAAATGCTGGGGGTGCTGGCGCCG
CTTGAGCGACAGGAAACTTTTTTTCGCTTCTGGGCCTGCAAAGAAGCCTACATCAAGGCGTGCGGCAAGGGATTGGCCTT
GGCCCTCGATCAGTTCGACGTGGCGATCGAACCAGACGGTGGCGTAAGCTTACTGGCCAATCGACAGGAGCGGGATGCTC
ATCCCGGGCATTGGGCCATCCGGCAAATCGAGCCTGGCAAGAACTACGTGGCGGCGGTGGCGGTCGGCGACGCCGCCTGG
AACCTCCGCTGCTGGCAGTGGCAGGACGATCATTTCAATTGGGAGGAAGACTGCCACCAGGATTCCTGCCAGACCTACGA
CGAGTGA

Upstream 100 bases:

>100_bases
TATCCCGGCGATCACTTTTTTATCCATGACGACAAACTGCCGCTGGTTGCGGTGATCGCCGCACAATTGCACAGCGAAGG
TTGGATCCAAGGAGGGGCCC

Downstream 100 bases:

>100_bases
CCGGCTTCGCAGGCGGCGGGATTCGCTGCCCGCGCAGGTAGCTCACGTCGGTTTAGCGAGCAATAGGGCCAGGCTTCTGC
CGGCTTCGTCCCTGGCGTTT

Product: hypothetical protein

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPEYDRSLWRPAPRQPGLGADDVHVWRACLMQPDARVLELVETLSEDERHRAERYRFVGDKRRFIVARGLLRRILRCYLE
IPAAQIRFSYGIKGKPALALPGCTLQFNLSHSREVVLIALTLRRDIGIDLELVRSLAAMDQMAERFFSAHEKQMLGVLAP
LERQETFFRFWACKEAYIKACGKGLALALDQFDVAIEPDGGVSLLANRQERDAHPGHWAIRQIEPGKNYVAAVAVGDAAW
NLRCWQWQDDHFNWEEDCHQDSCQTYDE

Sequences:

>Translated_268_residues
MPEYDRSLWRPAPRQPGLGADDVHVWRACLMQPDARVLELVETLSEDERHRAERYRFVGDKRRFIVARGLLRRILRCYLE
IPAAQIRFSYGIKGKPALALPGCTLQFNLSHSREVVLIALTLRRDIGIDLELVRSLAAMDQMAERFFSAHEKQMLGVLAP
LERQETFFRFWACKEAYIKACGKGLALALDQFDVAIEPDGGVSLLANRQERDAHPGHWAIRQIEPGKNYVAAVAVGDAAW
NLRCWQWQDDHFNWEEDCHQDSCQTYDE
>Mature_267_residues
PEYDRSLWRPAPRQPGLGADDVHVWRACLMQPDARVLELVETLSEDERHRAERYRFVGDKRRFIVARGLLRRILRCYLEI
PAAQIRFSYGIKGKPALALPGCTLQFNLSHSREVVLIALTLRRDIGIDLELVRSLAAMDQMAERFFSAHEKQMLGVLAPL
ERQETFFRFWACKEAYIKACGKGLALALDQFDVAIEPDGGVSLLANRQERDAHPGHWAIRQIEPGKNYVAAVAVGDAAWN
LRCWQWQDDHFNWEEDCHQDSCQTYDE

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=168, Percent_Identity=27.3809523809524, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789886, Length=122, Percent_Identity=34.4262295081967, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24663173, Length=242, Percent_Identity=25.6198347107438, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 30850; Mature: 30718

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEYDRSLWRPAPRQPGLGADDVHVWRACLMQPDARVLELVETLSEDERHRAERYRFVGD
CCCCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHCCC
KRRFIVARGLLRRILRCYLEIPAAQIRFSYGIKGKPALALPGCTLQFNLSHSREVVLIAL
CHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCEECCCCEEEEECCCCCEEEEEEE
TLRRDIGIDLELVRSLAAMDQMAERFFSAHEKQMLGVLAPLERQETFFRFWACKEAYIKA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
CGKGLALALDQFDVAIEPDGGVSLLANRQERDAHPGHWAIRQIEPGKNYVAAVAVGDAAW
HCCCCEEEEECCEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEE
NLRCWQWQDDHFNWEEDCHQDSCQTYDE
CEEEEEECCCCCCCHHHHCHHHHCCCCC
>Mature Secondary Structure 
PEYDRSLWRPAPRQPGLGADDVHVWRACLMQPDARVLELVETLSEDERHRAERYRFVGD
CCCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHCCC
KRRFIVARGLLRRILRCYLEIPAAQIRFSYGIKGKPALALPGCTLQFNLSHSREVVLIAL
CHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCEECCCCEEEEECCCCCEEEEEEE
TLRRDIGIDLELVRSLAAMDQMAERFFSAHEKQMLGVLAPLERQETFFRFWACKEAYIKA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
CGKGLALALDQFDVAIEPDGGVSLLANRQERDAHPGHWAIRQIEPGKNYVAAVAVGDAAW
HCCCCEEEEECCEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCEE
NLRCWQWQDDHFNWEEDCHQDSCQTYDE
CEEEEEECCCCCCCHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]