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The map label for this gene is xerD [H]

Identifier: 37522020

GI number: 37522020

Start: 2607000

End: 2607869

Strand: Direct

Name: xerD [H]

Synonym: glr2451

Alternate gene names: 37522020

Gene position: 2607000-2607869 (Clockwise)

Preceding gene: 37522019

Following gene: 37522021

Centisome position: 55.96

GC content: 64.83

Gene sequence:

>870_bases
ATGAATCTGCGCGATGCTGTCGAGCACTGGCTCGATCATCTGATTGCCGCACGTTCCCTGGCGGGCAACACCCTCAAAGC
CTACCAGCGCGATCTCGAAGAGTTCGCCCGCTTTGTGGAGAGCGAGCACCTCGACTGGCAGACCTTTGGAGCCACAGGCA
CCCACCACTTCGCCCAGATTCTGCAAAAAACGCATACTCCGCGCTCGGCGGCGCGCAAGCTTTCGGCCCTGCGCACTTTT
TATCGCCACGCCCTGGTGCAGGGCTGGGCAGGGGGCGTGCCTCCCGCCTGCACCCGCACCCTGCCGTCCGCCGAGCGCGG
CCTGCCGCGCATCCTGAGCGTCGCTCAAACCGAAAAGCTCATCGAGAGCGCGGCTTCGCCACTGGAATCGGCGGTGCTCG
AATTGCTCTACGCCACCGGGCTCAAAGCGGGGGAGCTGTGCGAATTGCGGGTGCGGGATGTGGCTTTTGCCGAAGCTTAT
CTAAGCGTCCAACCGGCCGCTTCCCAGCCGCGGGTGGTACCGGTGGGAGAACCAGCCCTGGCCGCTGTCGAAGCTTATCT
GGGGAGCGAACCTGTCCTGCCCGAGCGCTGGTTGTTCGTGGGTCGCCAGAATCGCCCCCTTAACCGATTCCACATCTACC
GGATCGTGCGGGAGGCGGCGGCGCGCTCGGCGATCGACTGGCCGGTTACCCCCGACACCCTGCGCCACAGTTTTGCTGTG
CATCTGCTTGAGGGCGGCGCGGATCTGGCTACCGTCCGCGAACTTTTGGGCCACGCGAGCCTTGCAACCACCGGAATCTA
CACCCGCCTCGCCCGCAATTACGCAGTCGGCCGTCCGCGGGCCGACAGTACGCCAAACCATCCCGGATAA

Upstream 100 bases:

>100_bases
CCTCGGGAGCCAGGGCCGCAAAAGAACTGGGCTGGCAATCGCGGCCTTTGCGTCCGGCGATAGCCGAAACCATCCGCTGG
TACCAGGAGCACCCGGCGGG

Downstream 100 bases:

>100_bases
TCGAAGCACAACGACCCACAAAACCCTTGTCCGACACCATCTGCGCCATCGCCACCGCCATCGTCCCCCAGCAAGGCAGC
GTCGGGATCGTGCGTTTGTC

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNLRDAVEHWLDHLIAARSLAGNTLKAYQRDLEEFARFVESEHLDWQTFGATGTHHFAQILQKTHTPRSAARKLSALRTF
YRHALVQGWAGGVPPACTRTLPSAERGLPRILSVAQTEKLIESAASPLESAVLELLYATGLKAGELCELRVRDVAFAEAY
LSVQPAASQPRVVPVGEPALAAVEAYLGSEPVLPERWLFVGRQNRPLNRFHIYRIVREAAARSAIDWPVTPDTLRHSFAV
HLLEGGADLATVRELLGHASLATTGIYTRLARNYAVGRPRADSTPNHPG

Sequences:

>Translated_289_residues
MNLRDAVEHWLDHLIAARSLAGNTLKAYQRDLEEFARFVESEHLDWQTFGATGTHHFAQILQKTHTPRSAARKLSALRTF
YRHALVQGWAGGVPPACTRTLPSAERGLPRILSVAQTEKLIESAASPLESAVLELLYATGLKAGELCELRVRDVAFAEAY
LSVQPAASQPRVVPVGEPALAAVEAYLGSEPVLPERWLFVGRQNRPLNRFHIYRIVREAAARSAIDWPVTPDTLRHSFAV
HLLEGGADLATVRELLGHASLATTGIYTRLARNYAVGRPRADSTPNHPG
>Mature_289_residues
MNLRDAVEHWLDHLIAARSLAGNTLKAYQRDLEEFARFVESEHLDWQTFGATGTHHFAQILQKTHTPRSAARKLSALRTF
YRHALVQGWAGGVPPACTRTLPSAERGLPRILSVAQTEKLIESAASPLESAVLELLYATGLKAGELCELRVRDVAFAEAY
LSVQPAASQPRVVPVGEPALAAVEAYLGSEPVLPERWLFVGRQNRPLNRFHIYRIVREAAARSAIDWPVTPDTLRHSFAV
HLLEGGADLATVRELLGHASLATTGIYTRLARNYAVGRPRADSTPNHPG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=33.6734693877551, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=32.4232081911263, Blast_Score=124, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 31812; Mature: 31812

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRDAVEHWLDHLIAARSLAGNTLKAYQRDLEEFARFVESEHLDWQTFGATGTHHFAQI
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LQKTHTPRSAARKLSALRTFYRHALVQGWAGGVPPACTRTLPSAERGLPRILSVAQTEKL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCHHHHHHHHHHHHH
IESAASPLESAVLELLYATGLKAGELCELRVRDVAFAEAYLSVQPAASQPRVVPVGEPAL
HHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHH
AAVEAYLGSEPVLPERWLFVGRQNRPLNRFHIYRIVREAAARSAIDWPVTPDTLRHSFAV
HHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
HLLEGGADLATVRELLGHASLATTGIYTRLARNYAVGRPRADSTPNHPG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLRDAVEHWLDHLIAARSLAGNTLKAYQRDLEEFARFVESEHLDWQTFGATGTHHFAQI
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LQKTHTPRSAARKLSALRTFYRHALVQGWAGGVPPACTRTLPSAERGLPRILSVAQTEKL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCHHHHHHHHHHHHH
IESAASPLESAVLELLYATGLKAGELCELRVRDVAFAEAYLSVQPAASQPRVVPVGEPAL
HHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHH
AAVEAYLGSEPVLPERWLFVGRQNRPLNRFHIYRIVREAAARSAIDWPVTPDTLRHSFAV
HHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
HLLEGGADLATVRELLGHASLATTGIYTRLARNYAVGRPRADSTPNHPG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]