Click here to switch to the map view.

The map label for this gene is aroQ

Identifier: 37522011

GI number: 37522011

Start: 2598254

End: 2598736

Strand: Direct

Name: aroQ

Synonym: gvip339

Alternate gene names: 37522011

Gene position: 2598254-2598736 (Clockwise)

Preceding gene: 37522010

Following gene: 37522012

Centisome position: 55.77

GC content: 63.77

Gene sequence:

>483_bases
GTGCCGATCGCCGCTAGTTTGCGGGTTTTGCTGCTGAACGGCCCCAACCTCAGCCTGCTGGGCAGGCGCGAGGTCGATGT
CTACGGGACCGTCACCTTGGCCGATATCGAACGCACCCTACAACTCGACGCTCAAGATCTGGACGTCGAGTTGTCTTGTT
TGCAGTCCAACCATGAAGGGGTGCTCATCGACGCCATCCACGACGCTTTCGGGCGCTGCGACGGGCTGGTGATCAACCCG
GGGGGGTTGACCCACACCAGCGTCGCCCTGCGCGATGCGATCGCCGGCGTCGGCCTACCCACGGTCGAAGTGCATATGAG
CAATGTCTATCGGCGTGAGAGCTTTCGCCACCATTCGTTTATCGCCCCGGTGGCGGTGGGACAAATCAGTGGCTTCGGCG
CCGACAGCTACCGGCTCGGCCTGCGGGCCATCGCTCTGTTCCTGCGTCGGCGGGCCGAGCAGGACGAGGGTCCCTGTCGA
TAG

Upstream 100 bases:

>100_bases
AGTGTTGCAGATAAGATTCAACGTGCGCTTGAGCGTCTGGCGGAGCTGTTAGGGCTGCCGCAACGCGCTCCCCAACTGCA
GCGCGTCCCCGTCAGAGTTC

Downstream 100 bases:

>100_bases
ACTGGAAAGGCAACCCTTTTGGCGAATCGCTCCATGCGCGCATCGAAACTGGCGGCACTGTTGCTCGTTTTTTTCCCCTG
GTACCCAGCCCAGGCGGCGC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MPIAASLRVLLLNGPNLSLLGRREVDVYGTVTLADIERTLQLDAQDLDVELSCLQSNHEGVLIDAIHDAFGRCDGLVINP
GGLTHTSVALRDAIAGVGLPTVEVHMSNVYRRESFRHHSFIAPVAVGQISGFGADSYRLGLRAIALFLRRRAEQDEGPCR

Sequences:

>Translated_160_residues
MPIAASLRVLLLNGPNLSLLGRREVDVYGTVTLADIERTLQLDAQDLDVELSCLQSNHEGVLIDAIHDAFGRCDGLVINP
GGLTHTSVALRDAIAGVGLPTVEVHMSNVYRRESFRHHSFIAPVAVGQISGFGADSYRLGLRAIALFLRRRAEQDEGPCR
>Mature_159_residues
PIAASLRVLLLNGPNLSLLGRREVDVYGTVTLADIERTLQLDAQDLDVELSCLQSNHEGVLIDAIHDAFGRCDGLVINPG
GLTHTSVALRDAIAGVGLPTVEVHMSNVYRRESFRHHSFIAPVAVGQISGFGADSYRLGLRAIALFLRRRAEQDEGPCR

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_GLOVI (Q7NHU3)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925388.1
- ProteinModelPortal:   Q7NHU3
- SMR:   Q7NHU3
- GeneID:   2600843
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.2442
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- ProtClustDB:   PRK05395
- BioCyc:   GVIO251221:GLR2442-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 17369; Mature: 17238

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 28-28 ACT_SITE 105-105 BINDING 79-79 BINDING 85-85 BINDING 92-92 BINDING 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAASLRVLLLNGPNLSLLGRREVDVYGTVTLADIERTLQLDAQDLDVELSCLQSNHEG
CCCCCCEEEEEEECCCEEEEECCEEEEEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCE
VLIDAIHDAFGRCDGLVINPGGLTHTSVALRDAIAGVGLPTVEVHMSNVYRRESFRHHSF
EEEEHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCE
IAPVAVGQISGFGADSYRLGLRAIALFLRRRAEQDEGPCR
ECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PIAASLRVLLLNGPNLSLLGRREVDVYGTVTLADIERTLQLDAQDLDVELSCLQSNHEG
CCCCCEEEEEEECCCEEEEECCEEEEEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCE
VLIDAIHDAFGRCDGLVINPGGLTHTSVALRDAIAGVGLPTVEVHMSNVYRRESFRHHSF
EEEEHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCE
IAPVAVGQISGFGADSYRLGLRAIALFLRRRAEQDEGPCR
ECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292