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The map label for this gene is cinA [C]

Identifier: 37522010

GI number: 37522010

Start: 2596839

End: 2598119

Strand: Direct

Name: cinA [C]

Synonym: glr2441

Alternate gene names: 37522010

Gene position: 2596839-2598119 (Clockwise)

Preceding gene: 37522007

Following gene: 37522011

Centisome position: 55.74

GC content: 66.51

Gene sequence:

>1281_bases
ATGGCCCCCAGCGCAGAGATTCTCTGTATCGGCACCGAACTGCTCCTTGGCCAGATCGTCAACACCAACGCCCAGTTTCT
GGCGGTCGAGCTGGCCAAACTGGGCATCCCCCATCACTTTCAGACCGTGGTGGGCGACAACCCCGGGCGCATCCGCCTCG
CCCTCGACATTGCCATCGAGCGCGCCGGGATTATCCTCACCACCGGCGGCCTCGGGCCGACCGACGACGATCTCACCCAC
CAGACGCTGGCGGAGCACTTCGAGGTGCCCCTGGTGCGTCACCCGGCGCTGCTGGCCCTCATCGAGGAGCGCTTTCGCGA
ACGCAACCGGCCGATGAGCCCCACCAACGCCAAACAGGCGGATCTGCCCGAAGGCGCCCAGATCCTGCCCAACCCGATGG
GCACAGCCCCCGGGATCGTCTGGGAACCGAAGGCCGGAGTGGCGATTCTCACTTTTCCGGGGGTGCCCGCCGAAATGCGT
GCCATGTGGGCCGAGACGGCCGTACCGTTTTTGCGCTTGCGCGGTGGGGGCCAGGAAATCTTCCACAGCCGCACGCTACG
CCATTGGGGTGTTTCGGAGTCCACCCTCGCTGAGAAGGTGGAAGAATTTCTCCGGGGCGTCAACCCCACCGTTGCCCCCT
ACGCGGGCAATGGCGAGGTGAAACTGCGCATCACCGCCCGGGCCGCAGGTATCGCAGCGGCCGAGTCGCTCATCGCCCCG
GTCGAAGCGAGCCTGCGCACCATCGCCGGTCTTGACTGCTACGGGGCGGACGAAGACACCCTTGCCTCGGCGAGTGCAGC
ACTTTTGGTCCGCACCGGCACCACCCTGGCGGTGGCCGAATCGTGCACCGGCGGCATGCTGGCCGAAGCCCTCACCGCCC
TGCCGGGAGCCTCGCGCTACTTGCGCGGAGCGGTGGTCGCCTACGCAAACGATCTCAAAACGTCGCTGCTCGGTGTCGAC
GAGCAACGGATGATCGACCACGGCGCGGTGAGCGAGCCGGTGGCCCGCGCTATGGCCGAGGGGGTACGCAATCGGCTTGC
CAGTGACTGGGGACTGGCGCTGACCGGTGTGTCCGGTCCGGGGGGCGGGACCGCCCAAAAACCCGTGGGGTTGGTGCACA
TCGCCCTTGCCGGACCGGGAGAGACTCGTGCGGTCGAAATCCGCCTTGGTGCGCAGCGCGGGCGCGACTGGATACGCCGG
GTGAGTACCCAGAGCGCCCTCGATCTCCTCCGCCGAGAGATCATCAACTGGGAAGCCTTTGGTATTATGAAAGAGCGATA
A

Upstream 100 bases:

>100_bases
CAATCGATAACAAACAACAAAGCGTGCGCATCGCGGTCTGGAACAAATTCTAGAGTTTTGGTTTTCCCCCCGGTGCCCCC
ATTCTAATGGACCGCCCCCA

Downstream 100 bases:

>100_bases
GGCAGCGTTCACCTTGAGAGATCACGGCATGGATAGTGTTGCAGATAAGATTCAACGTGCGCTTGAGCGTCTGGCGGAGC
TGTTAGGGCTGCCGCAACGC

Product: competence-damage inducible protein CinA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MAPSAEILCIGTELLLGQIVNTNAQFLAVELAKLGIPHHFQTVVGDNPGRIRLALDIAIERAGIILTTGGLGPTDDDLTH
QTLAEHFEVPLVRHPALLALIEERFRERNRPMSPTNAKQADLPEGAQILPNPMGTAPGIVWEPKAGVAILTFPGVPAEMR
AMWAETAVPFLRLRGGGQEIFHSRTLRHWGVSESTLAEKVEEFLRGVNPTVAPYAGNGEVKLRITARAAGIAAAESLIAP
VEASLRTIAGLDCYGADEDTLASASAALLVRTGTTLAVAESCTGGMLAEALTALPGASRYLRGAVVAYANDLKTSLLGVD
EQRMIDHGAVSEPVARAMAEGVRNRLASDWGLALTGVSGPGGGTAQKPVGLVHIALAGPGETRAVEIRLGAQRGRDWIRR
VSTQSALDLLRREIINWEAFGIMKER

Sequences:

>Translated_426_residues
MAPSAEILCIGTELLLGQIVNTNAQFLAVELAKLGIPHHFQTVVGDNPGRIRLALDIAIERAGIILTTGGLGPTDDDLTH
QTLAEHFEVPLVRHPALLALIEERFRERNRPMSPTNAKQADLPEGAQILPNPMGTAPGIVWEPKAGVAILTFPGVPAEMR
AMWAETAVPFLRLRGGGQEIFHSRTLRHWGVSESTLAEKVEEFLRGVNPTVAPYAGNGEVKLRITARAAGIAAAESLIAP
VEASLRTIAGLDCYGADEDTLASASAALLVRTGTTLAVAESCTGGMLAEALTALPGASRYLRGAVVAYANDLKTSLLGVD
EQRMIDHGAVSEPVARAMAEGVRNRLASDWGLALTGVSGPGGGTAQKPVGLVHIALAGPGETRAVEIRLGAQRGRDWIRR
VSTQSALDLLRREIINWEAFGIMKER
>Mature_425_residues
APSAEILCIGTELLLGQIVNTNAQFLAVELAKLGIPHHFQTVVGDNPGRIRLALDIAIERAGIILTTGGLGPTDDDLTHQ
TLAEHFEVPLVRHPALLALIEERFRERNRPMSPTNAKQADLPEGAQILPNPMGTAPGIVWEPKAGVAILTFPGVPAEMRA
MWAETAVPFLRLRGGGQEIFHSRTLRHWGVSESTLAEKVEEFLRGVNPTVAPYAGNGEVKLRITARAAGIAAAESLIAPV
EASLRTIAGLDCYGADEDTLASASAALLVRTGTTLAVAESCTGGMLAEALTALPGASRYLRGAVVAYANDLKTSLLGVDE
QRMIDHGAVSEPVARAMAEGVRNRLASDWGLALTGVSGPGGGTAQKPVGLVHIALAGPGETRAVEIRLGAQRGRDWIRRV
STQSALDLLRREIINWEAFGIMKER

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=408, Percent_Identity=30.8823529411765, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789052, Length=147, Percent_Identity=38.7755102040816, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1787818, Length=122, Percent_Identity=37.7049180327869, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_GLOVI (Q7NHU4)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925387.1
- ProteinModelPortal:   Q7NHU4
- SMR:   Q7NHU4
- GeneID:   2600842
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr2441
- NMPDR:   fig|251221.1.peg.2441
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- BioCyc:   GVIO251221:GLR2441-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45206; Mature: 45074

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSAEILCIGTELLLGQIVNTNAQFLAVELAKLGIPHHFQTVVGDNPGRIRLALDIAIE
CCCCCCEEEEEHHHHHHHHHCCCHHHEEHHHHHCCCCHHHHHHHCCCCCEEEEEEEEEEE
RAGIILTTGGLGPTDDDLTHQTLAEHFEVPLVRHPALLALIEERFRERNRPMSPTNAKQA
CCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DLPEGAQILPNPMGTAPGIVWEPKAGVAILTFPGVPAEMRAMWAETAVPFLRLRGGGQEI
CCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCHHH
FHSRTLRHWGVSESTLAEKVEEFLRGVNPTVAPYAGNGEVKLRITARAAGIAAAESLIAP
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEEECHHHHHHHHHHHHH
VEASLRTIAGLDCYGADEDTLASASAALLVRTGTTLAVAESCTGGMLAEALTALPGASRY
HHHHHHHHHCCCCCCCCHHHHHHCCEEEEEECCCEEEEHHCCCCHHHHHHHHHCCCCHHH
LRGAVVAYANDLKTSLLGVDEQRMIDHGAVSEPVARAMAEGVRNRLASDWGLALTGVSGP
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
GGGTAQKPVGLVHIALAGPGETRAVEIRLGAQRGRDWIRRVSTQSALDLLRREIINWEAF
CCCCCCCCCEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
GIMKER
EEECCC
>Mature Secondary Structure 
APSAEILCIGTELLLGQIVNTNAQFLAVELAKLGIPHHFQTVVGDNPGRIRLALDIAIE
CCCCCEEEEEHHHHHHHHHCCCHHHEEHHHHHCCCCHHHHHHHCCCCCEEEEEEEEEEE
RAGIILTTGGLGPTDDDLTHQTLAEHFEVPLVRHPALLALIEERFRERNRPMSPTNAKQA
CCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DLPEGAQILPNPMGTAPGIVWEPKAGVAILTFPGVPAEMRAMWAETAVPFLRLRGGGQEI
CCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCHHH
FHSRTLRHWGVSESTLAEKVEEFLRGVNPTVAPYAGNGEVKLRITARAAGIAAAESLIAP
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEEECHHHHHHHHHHHHH
VEASLRTIAGLDCYGADEDTLASASAALLVRTGTTLAVAESCTGGMLAEALTALPGASRY
HHHHHHHHHCCCCCCCCHHHHHHCCEEEEEECCCEEEEHHCCCCHHHHHHHHHCCCCHHH
LRGAVVAYANDLKTSLLGVDEQRMIDHGAVSEPVARAMAEGVRNRLASDWGLALTGVSGP
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
GGGTAQKPVGLVHIALAGPGETRAVEIRLGAQRGRDWIRRVSTQSALDLLRREIINWEAF
CCCCCCCCCEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
GIMKER
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292