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The map label for this gene is trxA [H]

Identifier: 37521287

GI number: 37521287

Start: 1827719

End: 1828258

Strand: Direct

Name: trxA [H]

Synonym: gvip237

Alternate gene names: 37521287

Gene position: 1827719-1828258 (Clockwise)

Preceding gene: 37521286

Following gene: 37521288

Centisome position: 39.23

GC content: 62.22

Gene sequence:

>540_bases
ATGGAAAGCGCCCCCGAGAACAAAACCGGCATCTGGCTGCGCAACGGCATCGTCGCGCTGGCCTCGGTGCTGATCGCGGT
GCTCGTCTTTTTTGCCGCCCGCAACCAGGCCCCGACGATGCAGCAGTTGGCGGCCGAGGCGGTGCCGTTGGACGAAGCCC
TCGCCAACGGCAAACCGACCCTGGTCGAGTTCTATGCCGACTGGTGCGCCAGTTGCCAGACGATGGCTCCGACTGTCGCC
AGGCTCAAGGAGCGCTACGGCGAGCAGGCCAACTTTGTGATGCTCAACGTCGATAATCCCCGCTGGCTGCCCGAACTGCA
GCAGTACAAGGTGTCTGGAATACCCCACTACGCATTTTTGGACGCGGCGGCCCGTCCTCTAGGATCGGCCATCGGTCTGC
AGCCCTCGCAGATATTGGAAGACAATTTAACCGCCCTGGCGGCGGGGGCTGAAACGCTTCCCAAGGCAGGTGCCCCCGCC
GGCCAGACTTCAAAATTCACGCCACCCAAAAAAGTCGACCAGCCCCGCGATCACTCTTAA

Upstream 100 bases:

>100_bases
AACGCTCAACAAAGCCCGCGGCATGCTCGAAACGATCGCCCGCCTCGCCCGGAGCGGGGGCGCGTCCGCTAACGTAGAAG
GGCAAGTGCAATAGCAACCC

Downstream 100 bases:

>100_bases
GATTCCTAGCGAGCAAGCCGTGAGCGAAGCGTTGCAACTGTGGCTGTATCAGATCGAGCAGGGGGCCGAGCAACTGGCCA
GGGCTCAGCTCACCCAGATT

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MESAPENKTGIWLRNGIVALASVLIAVLVFFAARNQAPTMQQLAAEAVPLDEALANGKPTLVEFYADWCASCQTMAPTVA
RLKERYGEQANFVMLNVDNPRWLPELQQYKVSGIPHYAFLDAAARPLGSAIGLQPSQILEDNLTALAAGAETLPKAGAPA
GQTSKFTPPKKVDQPRDHS

Sequences:

>Translated_179_residues
MESAPENKTGIWLRNGIVALASVLIAVLVFFAARNQAPTMQQLAAEAVPLDEALANGKPTLVEFYADWCASCQTMAPTVA
RLKERYGEQANFVMLNVDNPRWLPELQQYKVSGIPHYAFLDAAARPLGSAIGLQPSQILEDNLTALAAGAETLPKAGAPA
GQTSKFTPPKKVDQPRDHS
>Mature_179_residues
MESAPENKTGIWLRNGIVALASVLIAVLVFFAARNQAPTMQQLAAEAVPLDEALANGKPTLVEFYADWCASCQTMAPTVA
RLKERYGEQANFVMLNVDNPRWLPELQQYKVSGIPHYAFLDAAARPLGSAIGLQPSQILEDNLTALAAGAETLPKAGAPA
GQTSKFTPPKKVDQPRDHS

Specific function: Required for disulfide bond formation in some proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 19270; Mature: 19270

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAPENKTGIWLRNGIVALASVLIAVLVFFAARNQAPTMQQLAAEAVPLDEALANGKPT
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCCCH
LVEFYADWCASCQTMAPTVARLKERYGEQANFVMLNVDNPRWLPELQQYKVSGIPHYAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHH
DAAARPLGSAIGLQPSQILEDNLTALAAGAETLPKAGAPAGQTSKFTPPKKVDQPRDHS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MESAPENKTGIWLRNGIVALASVLIAVLVFFAARNQAPTMQQLAAEAVPLDEALANGKPT
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCCCH
LVEFYADWCASCQTMAPTVARLKERYGEQANFVMLNVDNPRWLPELQQYKVSGIPHYAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHH
DAAARPLGSAIGLQPSQILEDNLTALAAGAETLPKAGAPAGQTSKFTPPKKVDQPRDHS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]