Click here to switch to the map view.

The map label for this gene is rnr [C]

Identifier: 37521185

GI number: 37521185

Start: 1731378

End: 1733369

Strand: Reverse

Name: rnr [C]

Synonym: gll1616

Alternate gene names: 37521185

Gene position: 1733369-1731378 (Counterclockwise)

Preceding gene: 37521186

Following gene: 37521184

Centisome position: 37.2

GC content: 66.42

Gene sequence:

>1992_bases
GTGGAAAGAGGGACTCTGGTGGAATTTCGCCTGCAAGGAGGCCGGCGCTTGGGAGTGATCAGCGGCCCGGACGGCAAGAA
AAATTTCAACCTCCAGACCCAGACGGGCAACACCCAGACCGTGCATCCCCGGCAAATCACCTACCAGGTGGCCGGTGGCC
CCTACCGCACCAGCGAACTGCCGGCTTTTGAGTCGCAGGTGCAAAATTACCTGGACCAAGCAGATCTGGAGGTGGCCTGG
GAGCTTTTTCGCGAGAGCCACGCGCTGGTAAGCCCCGAGGATCTCGCCCAGCTGCTGTTTGACACCGCCGCTCCCGCCGC
TTGCTACGCGGCCCACTGTCTACTGAGCGAAGACCGGCTCTACTTCAAGCAAAAGGGCGACGGTTACGAGCCGCGCCCGA
CCGCCCAGGTCGAGGAGTTGCGCCACCAGCAGGCGGTCGAGCAGCGCAAAGCCCAGGAACAGGCGCGCTTTCTAGCCAGA
GTGCAATCGGTGTTGGGTGGGGCCGCAGACGAATGGGAGCCCAGCGACCGGTTGCGCCTCGATGCCCTCGAACGCTACGC
GCTGTGGGGAGACGAAGCTTCCGACCGCGCGAGCGCCCAGGACGTGCTGAGCCAGTTGGGCCACACCACCCGCAGCGAGG
ACGCGATTGCCCTTTTGGTCGCCCTCAGGCTCTGGTCGCCCCACGAAAATATTCACCTGCGCCGCTCGGGCATCCCGGTG
CACTTCGGCACTCCGGTAAGCGAATACGCCCGCAAGTTGCTGGAGAATCCGCCGGCCGATCCGGCCTCGCGCCGCGATTT
TGGGCGGCTTGCCATCTACACGATCGACGACGAATCGACCCGCGAAATCGACGACGGCTTGAGCCTTGAAATGCTCGAGG
ACGGCCGCGAAAAATTGTGGATCCACATCGCGGATCCGACCCGCTGGGTGCAGCCGGGCGACCCGCTCGAAGCGGAAGCC
CGGCGGCGGGCCACCAGCGTCTACCTGCCCACCGGCGCCATCCCGATGTTTCCGCCGGAACTGGCCACCGGTCCGATGAG
CCTGCTGCCGGGGCAACTCAACTGTGCTTTGAGCTTCGGCGCCATCATCGGTCCCGACGGTGCCGTCGAGAACTTCGAGG
TCACCCCGGCCCTGGTGCGCACGGTCTACCCGGTCACCTACGAAGAAGCCGACCCGCTTATCGCCAGCGGCGAGGAGCCG
GTGCTTGCGCGCCTGCACGAAATCGCCCTGGCCCGCCGCCGCCACCGCCACCAGCGCGGGGCGGTCAGCATCGACCTGCC
CGAAGCGCAGGTCAAAGTCAAAGATGACGAAATCCGCCTGGAGATTCTGGGGGATTCGGCTTCCCGGCTGCTGGTCTCCG
AGATGATGATCCTGGCGGGGGAACTGGCGGCGCGGCTGGCCATCGAGGCGGGCATCCCGGTGCCTTTTCGCACCCAACCG
GCGCCCGAACTGCCCCCTGCCGACGAGTTGCTGCGCCTGCCCGCCGGGCCGGTACGCGAATTTGCCGTCTGCCGCTGCAT
GCAGCGCGGCGAGGTGAGCGTCTACCCGGCCCGCCACGCCGGGTTGGGCCTCGACGCCTACACCCAGGCCACCTCGCCCA
TCCGCCGCTACAGCGACCTGCTGGTGCACTTTCAAATCAAGGCCCACCTGCGCCACGAGCCGCTCCCGCTGACCCTGGAG
CACCTCAAAGAGTTACTCGCCATGATCGACGCCGCCGGCCAAGAGGTCACCCAGATCGAGCGGCTCTCGGAGCGCTATTG
GATCTACGAGTACCTGCGCCACCGCCGCCACCAGGTCCAGCCCGGTCTGGTGCTCGACTATCTGGGCGGCGACCCGCAGC
GGGCGCTGGTGCTGCTCGAGAGCGTCGCCCTCAGGCTGCCGGTGCGCCTCGACCGGCCCGTCTCCAAAGGTGAGATGGTC
GATTTACAGATCGTGCAGGTGGACCCGCGCCAGGATCTGCTGGTACTCAAGGAAGTGCGCCAGGCCCACTGA

Upstream 100 bases:

>100_bases
CCTACAGACTTGCGCCATTGCAGAGAATTGCGTCAATCGCTTCCGAGCGGCGCGGGCCTGCGGATAAAGTAGTCAGGTAC
TGCGCACTGGCTGGACGTTT

Downstream 100 bases:

>100_bases
CGGTTACCCTGGGAAAGATAGCGACGCCTGGAGCCCATGGAGCAGGTACTGCAATATCTTGGCCGGTTTTTTACCCAGCC
GCTGTTTACGATCAGCGGCA

Product: ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MERGTLVEFRLQGGRRLGVISGPDGKKNFNLQTQTGNTQTVHPRQITYQVAGGPYRTSELPAFESQVQNYLDQADLEVAW
ELFRESHALVSPEDLAQLLFDTAAPAACYAAHCLLSEDRLYFKQKGDGYEPRPTAQVEELRHQQAVEQRKAQEQARFLAR
VQSVLGGAADEWEPSDRLRLDALERYALWGDEASDRASAQDVLSQLGHTTRSEDAIALLVALRLWSPHENIHLRRSGIPV
HFGTPVSEYARKLLENPPADPASRRDFGRLAIYTIDDESTREIDDGLSLEMLEDGREKLWIHIADPTRWVQPGDPLEAEA
RRRATSVYLPTGAIPMFPPELATGPMSLLPGQLNCALSFGAIIGPDGAVENFEVTPALVRTVYPVTYEEADPLIASGEEP
VLARLHEIALARRRHRHQRGAVSIDLPEAQVKVKDDEIRLEILGDSASRLLVSEMMILAGELAARLAIEAGIPVPFRTQP
APELPPADELLRLPAGPVREFAVCRCMQRGEVSVYPARHAGLGLDAYTQATSPIRRYSDLLVHFQIKAHLRHEPLPLTLE
HLKELLAMIDAAGQEVTQIERLSERYWIYEYLRHRRHQVQPGLVLDYLGGDPQRALVLLESVALRLPVRLDRPVSKGEMV
DLQIVQVDPRQDLLVLKEVRQAH

Sequences:

>Translated_663_residues
MERGTLVEFRLQGGRRLGVISGPDGKKNFNLQTQTGNTQTVHPRQITYQVAGGPYRTSELPAFESQVQNYLDQADLEVAW
ELFRESHALVSPEDLAQLLFDTAAPAACYAAHCLLSEDRLYFKQKGDGYEPRPTAQVEELRHQQAVEQRKAQEQARFLAR
VQSVLGGAADEWEPSDRLRLDALERYALWGDEASDRASAQDVLSQLGHTTRSEDAIALLVALRLWSPHENIHLRRSGIPV
HFGTPVSEYARKLLENPPADPASRRDFGRLAIYTIDDESTREIDDGLSLEMLEDGREKLWIHIADPTRWVQPGDPLEAEA
RRRATSVYLPTGAIPMFPPELATGPMSLLPGQLNCALSFGAIIGPDGAVENFEVTPALVRTVYPVTYEEADPLIASGEEP
VLARLHEIALARRRHRHQRGAVSIDLPEAQVKVKDDEIRLEILGDSASRLLVSEMMILAGELAARLAIEAGIPVPFRTQP
APELPPADELLRLPAGPVREFAVCRCMQRGEVSVYPARHAGLGLDAYTQATSPIRRYSDLLVHFQIKAHLRHEPLPLTLE
HLKELLAMIDAAGQEVTQIERLSERYWIYEYLRHRRHQVQPGLVLDYLGGDPQRALVLLESVALRLPVRLDRPVSKGEMV
DLQIVQVDPRQDLLVLKEVRQAH
>Mature_663_residues
MERGTLVEFRLQGGRRLGVISGPDGKKNFNLQTQTGNTQTVHPRQITYQVAGGPYRTSELPAFESQVQNYLDQADLEVAW
ELFRESHALVSPEDLAQLLFDTAAPAACYAAHCLLSEDRLYFKQKGDGYEPRPTAQVEELRHQQAVEQRKAQEQARFLAR
VQSVLGGAADEWEPSDRLRLDALERYALWGDEASDRASAQDVLSQLGHTTRSEDAIALLVALRLWSPHENIHLRRSGIPV
HFGTPVSEYARKLLENPPADPASRRDFGRLAIYTIDDESTREIDDGLSLEMLEDGREKLWIHIADPTRWVQPGDPLEAEA
RRRATSVYLPTGAIPMFPPELATGPMSLLPGQLNCALSFGAIIGPDGAVENFEVTPALVRTVYPVTYEEADPLIASGEEP
VLARLHEIALARRRHRHQRGAVSIDLPEAQVKVKDDEIRLEILGDSASRLLVSEMMILAGELAARLAIEAGIPVPFRTQP
APELPPADELLRLPAGPVREFAVCRCMQRGEVSVYPARHAGLGLDAYTQATSPIRRYSDLLVHFQIKAHLRHEPLPLTLE
HLKELLAMIDAAGQEVTQIERLSERYWIYEYLRHRRHQVQPGLVLDYLGGDPQRALVLLESVALRLPVRLDRPVSKGEMV
DLQIVQVDPRQDLLVLKEVRQAH

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=390, Percent_Identity=28.2051282051282, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI190014623, Length=331, Percent_Identity=26.5861027190332, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI190014625, Length=331, Percent_Identity=26.5861027190332, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI19115966, Length=352, Percent_Identity=26.4204545454545, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI219521928, Length=352, Percent_Identity=26.4204545454545, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI87082383, Length=371, Percent_Identity=29.6495956873315, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787542, Length=331, Percent_Identity=29.9093655589124, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17553506, Length=366, Percent_Identity=27.3224043715847, Blast_Score=99, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323943, Length=399, Percent_Identity=26.5664160401003, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6324552, Length=434, Percent_Identity=26.2672811059908, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24649634, Length=330, Percent_Identity=26.6666666666667, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654592, Length=360, Percent_Identity=26.1111111111111, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19922976, Length=360, Percent_Identity=26.1111111111111, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24654597, Length=360, Percent_Identity=26.1111111111111, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 74236; Mature: 74236

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERGTLVEFRLQGGRRLGVISGPDGKKNFNLQTQTGNTQTVHPRQITYQVAGGPYRTSEL
CCCCCEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCCEECCCEEEEEECCCCCCCCCC
PAFESQVQNYLDQADLEVAWELFRESHALVSPEDLAQLLFDTAAPAACYAAHCLLSEDRL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
YFKQKGDGYEPRPTAQVEELRHQQAVEQRKAQEQARFLARVQSVLGGAADEWEPSDRLRL
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
DALERYALWGDEASDRASAQDVLSQLGHTTRSEDAIALLVALRLWSPHENIHLRRSGIPV
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCE
HFGTPVSEYARKLLENPPADPASRRDFGRLAIYTIDDESTREIDDGLSLEMLEDGREKLW
EECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCHHHHHCCCEEEE
IHIADPTRWVQPGDPLEAEARRRATSVYLPTGAIPMFPPELATGPMSLLPGQLNCALSFG
EEECCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCHHHCCCCHHHCCCCEEEEEEEC
AIIGPDGAVENFEVTPALVRTVYPVTYEEADPLIASGEEPVLARLHEIALARRRHRHQRG
CEECCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
AVSIDLPEAQVKVKDDEIRLEILGDSASRLLVSEMMILAGELAARLAIEAGIPVPFRTQP
CEEEECCCCEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
APELPPADELLRLPAGPVREFAVCRCMQRGEVSVYPARHAGLGLDAYTQATSPIRRYSDL
CCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHH
LVHFQIKAHLRHEPLPLTLEHLKELLAMIDAAGQEVTQIERLSERYWIYEYLRHRRHQVQ
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGLVLDYLGGDPQRALVLLESVALRLPVRLDRPVSKGEMVDLQIVQVDPRQDLLVLKEVR
CCEEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEEECCCCHHHHHHHHH
QAH
HCC
>Mature Secondary Structure
MERGTLVEFRLQGGRRLGVISGPDGKKNFNLQTQTGNTQTVHPRQITYQVAGGPYRTSEL
CCCCCEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCCEECCCEEEEEECCCCCCCCCC
PAFESQVQNYLDQADLEVAWELFRESHALVSPEDLAQLLFDTAAPAACYAAHCLLSEDRL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
YFKQKGDGYEPRPTAQVEELRHQQAVEQRKAQEQARFLARVQSVLGGAADEWEPSDRLRL
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
DALERYALWGDEASDRASAQDVLSQLGHTTRSEDAIALLVALRLWSPHENIHLRRSGIPV
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCE
HFGTPVSEYARKLLENPPADPASRRDFGRLAIYTIDDESTREIDDGLSLEMLEDGREKLW
EECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCCCCHHHHHCCCEEEE
IHIADPTRWVQPGDPLEAEARRRATSVYLPTGAIPMFPPELATGPMSLLPGQLNCALSFG
EEECCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCHHHCCCCHHHCCCCEEEEEEEC
AIIGPDGAVENFEVTPALVRTVYPVTYEEADPLIASGEEPVLARLHEIALARRRHRHQRG
CEECCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
AVSIDLPEAQVKVKDDEIRLEILGDSASRLLVSEMMILAGELAARLAIEAGIPVPFRTQP
CEEEECCCCEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
APELPPADELLRLPAGPVREFAVCRCMQRGEVSVYPARHAGLGLDAYTQATSPIRRYSDL
CCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHH
LVHFQIKAHLRHEPLPLTLEHLKELLAMIDAAGQEVTQIERLSERYWIYEYLRHRRHQVQ
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGLVLDYLGGDPQRALVLLESVALRLPVRLDRPVSKGEMVDLQIVQVDPRQDLLVLKEVR
CCEEEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEEECCCCHHHHHHHHH
QAH
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]