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The map label for this gene is yhdN [H]

Identifier: 37521186

GI number: 37521186

Start: 1733734

End: 1734678

Strand: Reverse

Name: yhdN [H]

Synonym: gll1617

Alternate gene names: 37521186

Gene position: 1734678-1733734 (Counterclockwise)

Preceding gene: 37521187

Following gene: 37521185

Centisome position: 37.23

GC content: 64.66

Gene sequence:

>945_bases
ATGGAAACGCGCCGGCTTGGTACCAACGGCCCGCACATCACCACAATCGGCTTCGGGGCCTGGGCCGTCGACGGACCCTG
GCAGTTCGGTTGGGGACCGGTGGACGACCGCGAATCGGCAGCAGCAATTCGCGCCGCCCTCGACGCCGGGGTCAACTGGA
TCGATACCGCCGCGGTCTATGGCTTCGGCCACTCGGAGAAGATCGTGGGTGAGGCGGTCAAAGGCCGCCGCGACGAGGTG
TTCATCGCCACCAAGTGCGGCTTGCTCGGAGGGGAGACCAAAAGCCCCGTGCGCTCGCTGAGGCCCAAGTCGATCACAGC
CGAGGCCGATGCGAGCCTGCGGCGTCTGGGGGTGGATCACATCGACCTCTACCAGTTCCACTGGCCGGATGTGAATACGC
CGGTCGAGGACTCCTGGGGCGCGATGGTGGAATTGGTCGAAGCGGGCAAAGTGCGCTATGCCGGCGTGTCCAATTTCGAT
GTGCCGCTGCTTGAAAAAATTCTGCCCATCCATCCGGTCACCTCGCTGCAGCCACCCTACAGCCTCATCAAGCGCGGCAT
CGAGGCGGAACTGGTGCCGTTTTGCCGCGAGCACGGCATCGGCATCGTCGTCTACAGCCCCATGCAGGCGGGTTTGCTCA
CCGGCAAGTTCGATCCCGACCGCCTTGCCCCCGACGACTGGCGACGGCGGGCCGCCTGGTTCGCGCCCGAAAATCTCGAT
CGCAATTTGGCCCTCGTCGAGCACCTGCGGCCGATCGCCGCGCGCTACGGCAAGAGCGTCGGACAGTTGGCCATCGCCTG
GGTGCTGCGCGATACGGCTGTCACTTCCGCGATCGTGGGCGCCCGCCGGCCGGATCAAGTCAGAGAGAACGTCGAAGCTT
CGGGATTTCACCTCGGGGAGGCAGATCTGGCCGAAATCGAGGCAATCCTGGCTACTCAAAGTTGA

Upstream 100 bases:

>100_bases
TCTCCGGGTGCCCAGGTCTCCGGAAGCGGGTGCTGAAGGCGGCGTTGGCTTTGGGTCTCCCAAGGGCGACACTGATGACA
GCGCTTGGGACAACGAAACG

Downstream 100 bases:

>100_bases
CAGACTTGTGCTCAAGTCTGTCTGCGAGCACATGCAGCGCAAGAGCCTGAACGACAGCCATTGCCCGTTCCCTTGTTTCC
TATAGGCAACAACACCGGGA

Product: oxidoreductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
METRRLGTNGPHITTIGFGAWAVDGPWQFGWGPVDDRESAAAIRAALDAGVNWIDTAAVYGFGHSEKIVGEAVKGRRDEV
FIATKCGLLGGETKSPVRSLRPKSITAEADASLRRLGVDHIDLYQFHWPDVNTPVEDSWGAMVELVEAGKVRYAGVSNFD
VPLLEKILPIHPVTSLQPPYSLIKRGIEAELVPFCREHGIGIVVYSPMQAGLLTGKFDPDRLAPDDWRRRAAWFAPENLD
RNLALVEHLRPIAARYGKSVGQLAIAWVLRDTAVTSAIVGARRPDQVRENVEASGFHLGEADLAEIEAILATQS

Sequences:

>Translated_314_residues
METRRLGTNGPHITTIGFGAWAVDGPWQFGWGPVDDRESAAAIRAALDAGVNWIDTAAVYGFGHSEKIVGEAVKGRRDEV
FIATKCGLLGGETKSPVRSLRPKSITAEADASLRRLGVDHIDLYQFHWPDVNTPVEDSWGAMVELVEAGKVRYAGVSNFD
VPLLEKILPIHPVTSLQPPYSLIKRGIEAELVPFCREHGIGIVVYSPMQAGLLTGKFDPDRLAPDDWRRRAAWFAPENLD
RNLALVEHLRPIAARYGKSVGQLAIAWVLRDTAVTSAIVGARRPDQVRENVEASGFHLGEADLAEIEAILATQS
>Mature_314_residues
METRRLGTNGPHITTIGFGAWAVDGPWQFGWGPVDDRESAAAIRAALDAGVNWIDTAAVYGFGHSEKIVGEAVKGRRDEV
FIATKCGLLGGETKSPVRSLRPKSITAEADASLRRLGVDHIDLYQFHWPDVNTPVEDSWGAMVELVEAGKVRYAGVSNFD
VPLLEKILPIHPVTSLQPPYSLIKRGIEAELVPFCREHGIGIVVYSPMQAGLLTGKFDPDRLAPDDWRRRAAWFAPENLD
RNLALVEHLRPIAARYGKSVGQLAIAWVLRDTAVTSAIVGARRPDQVRENVEASGFHLGEADLAEIEAILATQS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=30, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=29.9694189602446, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI27436964, Length=308, Percent_Identity=29.2207792207792, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI27436962, Length=308, Percent_Identity=29.2207792207792, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=29.2207792207792, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI27436971, Length=332, Percent_Identity=28.6144578313253, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI223718702, Length=292, Percent_Identity=32.5342465753425, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI41152114, Length=294, Percent_Identity=31.6326530612245, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI41327764, Length=282, Percent_Identity=31.5602836879433, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4502049, Length=334, Percent_Identity=25.748502994012, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5174695, Length=339, Percent_Identity=24.7787610619469, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI310109920, Length=338, Percent_Identity=22.4852071005917, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI310109922, Length=319, Percent_Identity=23.1974921630094, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI223718708, Length=129, Percent_Identity=37.984496124031, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788070, Length=317, Percent_Identity=37.5394321766561, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789375, Length=342, Percent_Identity=29.8245614035088, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=30.3125, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=29.6296296296296, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788081, Length=288, Percent_Identity=31.25, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=27.2151898734177, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87082198, Length=303, Percent_Identity=28.0528052805281, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI48994888, Length=313, Percent_Identity=27.7955271565495, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786400, Length=294, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=332, Percent_Identity=24.6987951807229, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17566692, Length=322, Percent_Identity=24.8447204968944, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550248, Length=327, Percent_Identity=27.5229357798165, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17537077, Length=293, Percent_Identity=24.9146757679181, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=29.673590504451, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=318, Percent_Identity=25.7861635220126, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320576, Length=342, Percent_Identity=28.0701754385965, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324694, Length=242, Percent_Identity=29.7520661157025, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=280, Percent_Identity=26.7857142857143, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=252, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320079, Length=267, Percent_Identity=25.0936329588015, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319625, Length=213, Percent_Identity=30.0469483568075, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24644950, Length=333, Percent_Identity=28.5285285285285, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24657054, Length=337, Percent_Identity=25.2225519287834, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646155, Length=313, Percent_Identity=24.2811501597444, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640980, Length=352, Percent_Identity=24.7159090909091, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45549126, Length=352, Percent_Identity=24.7159090909091, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646159, Length=311, Percent_Identity=25.4019292604502, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI45553081, Length=331, Percent_Identity=25.3776435045317, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24663317, Length=332, Percent_Identity=24.6987951807229, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI20129731, Length=335, Percent_Identity=25.6716417910448, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24662781, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34314; Mature: 34314

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRRLGTNGPHITTIGFGAWAVDGPWQFGWGPVDDRESAAAIRAALDAGVNWIDTAAVY
CCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
GFGHSEKIVGEAVKGRRDEVFIATKCGLLGGETKSPVRSLRPKSITAEADASLRRLGVDH
CCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCE
IDLYQFHWPDVNTPVEDSWGAMVELVEAGKVRYAGVSNFDVPLLEKILPIHPVTSLQPPY
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCCCCCCCCCH
SLIKRGIEAELVPFCREHGIGIVVYSPMQAGLLTGKFDPDRLAPDDWRRRAAWFAPENLD
HHHHCCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCC
RNLALVEHLRPIAARYGKSVGQLAIAWVLRDTAVTSAIVGARRPDQVRENVEASGFHLGE
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCC
ADLAEIEAILATQS
HHHHHHHHHHHCCC
>Mature Secondary Structure
METRRLGTNGPHITTIGFGAWAVDGPWQFGWGPVDDRESAAAIRAALDAGVNWIDTAAVY
CCCCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
GFGHSEKIVGEAVKGRRDEVFIATKCGLLGGETKSPVRSLRPKSITAEADASLRRLGVDH
CCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHCCCE
IDLYQFHWPDVNTPVEDSWGAMVELVEAGKVRYAGVSNFDVPLLEKILPIHPVTSLQPPY
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCCCCCCCCCH
SLIKRGIEAELVPFCREHGIGIVVYSPMQAGLLTGKFDPDRLAPDDWRRRAAWFAPENLD
HHHHCCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCC
RNLALVEHLRPIAARYGKSVGQLAIAWVLRDTAVTSAIVGARRPDQVRENVEASGFHLGE
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCC
ADLAEIEAILATQS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]