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The map label for this gene is ackA

Identifier: 37520569

GI number: 37520569

Start: 1071423

End: 1072640

Strand: Direct

Name: ackA

Synonym: glr1000

Alternate gene names: 37520569

Gene position: 1071423-1072640 (Clockwise)

Preceding gene: 37520568

Following gene: 37520572

Centisome position: 23.0

GC content: 64.53

Gene sequence:

>1218_bases
GTGAAAGTACTCGTTCTCAACGCCGGTTCGAGCAGCCAGAAAAGCTGCCTGTACGACCTGCCGCACACCCAGCTGCCCCA
GGAGCCGCCGCAGCCGCTGTGGGAAGCACAGATCGACTGGCCCCACGGCGGAGATGGCGCAAAGCTGAAGATCAAAACCG
TCCACCATCGACACGAAAAAACCCTGCAAGGCGGGTCGCGCTCCGAAGACAGCGCCCGGATGCTCGAAACTCTCTACAGC
GGCGAGACCCGGGTGATCGCAGATCCAAGCGAAATCGAGATGGTCGGACATCGGGTCGTCCACGGCGGTGAAGCGTACCG
CGAGAGCACCCGGATCACCCCCGAGGTGAAGGCAGCCATCGATCAGCTCGCACGCTTTGCGCCGGTGCATAACCCGGCCA
ACCTCGCCGGTATCGAAGCGCTCGAAGCGCTCCTCGGCCCGCAGGTGCCCCAAATCGCCGTTTTCGACACCGCCTTCCAC
AGCCGCCTGCCCGCTGCTGCCTACGTCTACCCCGGTCCTTACGAGTGGCTCGATCAGGGCATCCGTCGCTACGGCTTCCA
CGGCATCAGCCACCGCTACTGCGCCGAGCGCGCCGCCCAGATCCTCGGGCGCGACCTGGCGCAGTTGCGCCTGATCACCT
GTCATCTGGGCAACGGCTGTTCGCTCGCCGCCGTGCAGGGCGGCTTCAGCATCGATACCACCATGGGATTTACGCCCCTG
GAAGGACTGATGATGGGCAGCCGCTCAGGCTCCGTCGACCCCGGCATTTTGATTCATCTGATGCGCCAGGCCGACTACAC
CGTGGACAAGCTCGATCACATCCTCAACCAGGCTTCGGGGTTGGAAGGCGTCTCCGGGATTTCCAACGACCTGCGCCCGC
TCTTCAAAGCGATCGACGAAGGCAACGCCCGCGCCAAACTGGCGCTCGATATATACATCCACCGACTGCGTGCCGGGATC
GGAGCGATGGCCGTGAGCCTGGGCGGCCTCGACGCCTTGATCTTTACTGCCGGGGTGGGAGAAAACGCAGCCCCCGTGCG
CGCCGGAGCCTGCGAAGCGCTGGGATTTCTCGGGGTGGCCCTCGACCCCCAAAAGAACAACGGCCGACCCAGGGACGCAG
ACATTGCCGCCGCGGATTCAGCGGTGCGGGTGCTGGTCATTCACACCCAGGAGGACTGGGCGATTGCCCGGGAATGCTGG
CAGCACCTGCGCCGTTGA

Upstream 100 bases:

>100_bases
GTCAAATTCGACGTGCACGGACCGCTTTTAGAATCGCTCAACGACCGCGCCCACCTCGGTCAGGAGTTGCGCACCCTACC
GGGAACTTGAGGGCTGTGAG

Downstream 100 bases:

>100_bases
GGCGAATTCAGGCGGGCCGCTCCAACAGACTGGTCATCTCGAAGCTGGTGCGCTCGGCCACCTCGCGGCCCTCTTCGATG
AGGTACTGCAAGAACGTGCG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKVLVLNAGSSSQKSCLYDLPHTQLPQEPPQPLWEAQIDWPHGGDGAKLKIKTVHHRHEKTLQGGSRSEDSARMLETLYS
GETRVIADPSEIEMVGHRVVHGGEAYRESTRITPEVKAAIDQLARFAPVHNPANLAGIEALEALLGPQVPQIAVFDTAFH
SRLPAAAYVYPGPYEWLDQGIRRYGFHGISHRYCAERAAQILGRDLAQLRLITCHLGNGCSLAAVQGGFSIDTTMGFTPL
EGLMMGSRSGSVDPGILIHLMRQADYTVDKLDHILNQASGLEGVSGISNDLRPLFKAIDEGNARAKLALDIYIHRLRAGI
GAMAVSLGGLDALIFTAGVGENAAPVRAGACEALGFLGVALDPQKNNGRPRDADIAAADSAVRVLVIHTQEDWAIARECW
QHLRR

Sequences:

>Translated_405_residues
MKVLVLNAGSSSQKSCLYDLPHTQLPQEPPQPLWEAQIDWPHGGDGAKLKIKTVHHRHEKTLQGGSRSEDSARMLETLYS
GETRVIADPSEIEMVGHRVVHGGEAYRESTRITPEVKAAIDQLARFAPVHNPANLAGIEALEALLGPQVPQIAVFDTAFH
SRLPAAAYVYPGPYEWLDQGIRRYGFHGISHRYCAERAAQILGRDLAQLRLITCHLGNGCSLAAVQGGFSIDTTMGFTPL
EGLMMGSRSGSVDPGILIHLMRQADYTVDKLDHILNQASGLEGVSGISNDLRPLFKAIDEGNARAKLALDIYIHRLRAGI
GAMAVSLGGLDALIFTAGVGENAAPVRAGACEALGFLGVALDPQKNNGRPRDADIAAADSAVRVLVIHTQEDWAIARECW
QHLRR
>Mature_405_residues
MKVLVLNAGSSSQKSCLYDLPHTQLPQEPPQPLWEAQIDWPHGGDGAKLKIKTVHHRHEKTLQGGSRSEDSARMLETLYS
GETRVIADPSEIEMVGHRVVHGGEAYRESTRITPEVKAAIDQLARFAPVHNPANLAGIEALEALLGPQVPQIAVFDTAFH
SRLPAAAYVYPGPYEWLDQGIRRYGFHGISHRYCAERAAQILGRDLAQLRLITCHLGNGCSLAAVQGGFSIDTTMGFTPL
EGLMMGSRSGSVDPGILIHLMRQADYTVDKLDHILNQASGLEGVSGISNDLRPLFKAIDEGNARAKLALDIYIHRLRAGI
GAMAVSLGGLDALIFTAGVGENAAPVRAGACEALGFLGVALDPQKNNGRPRDADIAAADSAVRVLVIHTQEDWAIARECW
QHLRR

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=399, Percent_Identity=39.3483709273183, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1788633, Length=407, Percent_Identity=38.5749385749386, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_GLOVI (Q7NLW9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923946.1
- HSSP:   P38502
- ProteinModelPortal:   Q7NLW9
- SMR:   Q7NLW9
- GeneID:   2599118
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr1000
- NMPDR:   fig|251221.1.peg.1000
- HOGENOM:   HBG285863
- OMA:   GGELYSE
- ProtClustDB:   PRK00180
- BioCyc:   GVIO251221:GLR1000-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43835; Mature: 43835

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVLNAGSSSQKSCLYDLPHTQLPQEPPQPLWEAQIDWPHGGDGAKLKIKTVHHRHEK
CEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEHHHHHHH
TLQGGSRSEDSARMLETLYSGETRVIADPSEIEMVGHRVVHGGEAYRESTRITPEVKAAI
HHCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHH
DQLARFAPVHNPANLAGIEALEALLGPQVPQIAVFDTAFHSRLPAAAYVYPGPYEWLDQG
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCEEEECCCCHHHHHHH
IRRYGFHGISHRYCAERAAQILGRDLAQLRLITCHLGNGCSLAAVQGGFSIDTTMGFTPL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCEECCCCCCCCH
EGLMMGSRSGSVDPGILIHLMRQADYTVDKLDHILNQASGLEGVSGISNDLRPLFKAIDE
HHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHCC
GNARAKLALDIYIHRLRAGIGAMAVSLGGLDALIFTAGVGENAAPVRAGACEALGFLGVA
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHEEE
LDPQKNNGRPRDADIAAADSAVRVLVIHTQEDWAIARECWQHLRR
ECCCCCCCCCCCCCHHCCCCEEEEEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLVLNAGSSSQKSCLYDLPHTQLPQEPPQPLWEAQIDWPHGGDGAKLKIKTVHHRHEK
CEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEHHHHHHH
TLQGGSRSEDSARMLETLYSGETRVIADPSEIEMVGHRVVHGGEAYRESTRITPEVKAAI
HHCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHH
DQLARFAPVHNPANLAGIEALEALLGPQVPQIAVFDTAFHSRLPAAAYVYPGPYEWLDQG
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCEEEECCCCHHHHHHH
IRRYGFHGISHRYCAERAAQILGRDLAQLRLITCHLGNGCSLAAVQGGFSIDTTMGFTPL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCEECCCCCCCCH
EGLMMGSRSGSVDPGILIHLMRQADYTVDKLDHILNQASGLEGVSGISNDLRPLFKAIDE
HHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHCC
GNARAKLALDIYIHRLRAGIGAMAVSLGGLDALIFTAGVGENAAPVRAGACEALGFLGVA
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHEEE
LDPQKNNGRPRDADIAAADSAVRVLVIHTQEDWAIARECWQHLRR
ECCCCCCCCCCCCCHHCCCCEEEEEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292