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The map label for this gene is cobC [H]

Identifier: 37520568

GI number: 37520568

Start: 1070774

End: 1071412

Strand: Direct

Name: cobC [H]

Synonym: glr0999

Alternate gene names: 37520568

Gene position: 1070774-1071412 (Clockwise)

Preceding gene: 37520567

Following gene: 37520569

Centisome position: 22.98

GC content: 64.63

Gene sequence:

>639_bases
ATGAGCCTGCGGGTCCATTTTCTGCGCCACGGTGAGACGATCTACAGCCGCACGGGGGGCTACTGTGGCGAACTCGACCC
CGAGTTGACCGCTGAGGGCGAGATGATGGCGGCGGCGTTTGCCGCCGCCCACCGCTCCACCCCCTGGGATGCACTCTACG
TCAGTCCGATGCGGCGCACCGTGGCGACGGCCAGGCCCCTGTGCGAAGCCCTGGGATTGGAGATGCAGTTGCGCGACGGC
CTCAAAGAGATCCGCTACGGCGCATGGGAAGGCAAGACCAGCGACGATGTCAAAGCGCACTACGCCGACGATTACGGGCG
CTGGCTGACCGAACCCGCCTGGAACCCGCCCACCGGCGGCGAGACCTCAGTGGCGATCGCCAGCCGCGCCATGCCGGTGA
TCGCCGAGATCGAATCGAAGTATGCGGACGGCAACGTGCTTGTGGTTTCGCACAAGGCGACCATTCGCATTATGCTCTGC
TCGCTGTTGGGCATCGACCTCGGCCGCTACCGCGACCGCATCAACATCCTGGCGGCCTCGCTGAGTACGGTCAAATTCGA
CGTGCACGGACCGCTTTTAGAATCGCTCAACGACCGCGCCCACCTCGGTCAGGAGTTGCGCACCCTACCGGGAACTTGA

Upstream 100 bases:

>100_bases
GGGCGGTTGCGGTGGATGTGGTGCTGGAGGAGTACGTCCAGGCGACCGCCGGTCTCGCGGTCAAACCGCAGCCGGTGGCG
GCCACCTAAAGGAGAGGGGC

Downstream 100 bases:

>100_bases
GGGCTGTGAGGTGAAAGTACTCGTTCTCAACGCCGGTTCGAGCAGCCAGAAAAGCTGCCTGTACGACCTGCCGCACACCC
AGCTGCCCCAGGAGCCGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRVHFLRHGETIYSRTGGYCGELDPELTAEGEMMAAAFAAAHRSTPWDALYVSPMRRTVATARPLCEALGLEMQLRDG
LKEIRYGAWEGKTSDDVKAHYADDYGRWLTEPAWNPPTGGETSVAIASRAMPVIAEIESKYADGNVLVVSHKATIRIMLC
SLLGIDLGRYRDRINILAASLSTVKFDVHGPLLESLNDRAHLGQELRTLPGT

Sequences:

>Translated_212_residues
MSLRVHFLRHGETIYSRTGGYCGELDPELTAEGEMMAAAFAAAHRSTPWDALYVSPMRRTVATARPLCEALGLEMQLRDG
LKEIRYGAWEGKTSDDVKAHYADDYGRWLTEPAWNPPTGGETSVAIASRAMPVIAEIESKYADGNVLVVSHKATIRIMLC
SLLGIDLGRYRDRINILAASLSTVKFDVHGPLLESLNDRAHLGQELRTLPGT
>Mature_211_residues
SLRVHFLRHGETIYSRTGGYCGELDPELTAEGEMMAAAFAAAHRSTPWDALYVSPMRRTVATARPLCEALGLEMQLRDGL
KEIRYGAWEGKTSDDVKAHYADDYGRWLTEPAWNPPTGGETSVAIASRAMPVIAEIESKYADGNVLVVSHKATIRIMLCS
LLGIDLGRYRDRINILAASLSTVKFDVHGPLLESLNDRAHLGQELRTLPGT

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=163, Percent_Identity=28.8343558282209, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 23342; Mature: 23211

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRVHFLRHGETIYSRTGGYCGELDPELTAEGEMMAAAFAAAHRSTPWDALYVSPMRRT
CCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHH
VATARPLCEALGLEMQLRDGLKEIRYGAWEGKTSDDVKAHYADDYGRWLTEPAWNPPTGG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ETSVAIASRAMPVIAEIESKYADGNVLVVSHKATIRIMLCSLLGIDLGRYRDRINILAAS
CCHHHHHHHCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LSTVKFDVHGPLLESLNDRAHLGQELRTLPGT
HHEEEEECCCHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLRVHFLRHGETIYSRTGGYCGELDPELTAEGEMMAAAFAAAHRSTPWDALYVSPMRRT
CEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHH
VATARPLCEALGLEMQLRDGLKEIRYGAWEGKTSDDVKAHYADDYGRWLTEPAWNPPTGG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ETSVAIASRAMPVIAEIESKYADGNVLVVSHKATIRIMLCSLLGIDLGRYRDRINILAAS
CCHHHHHHHCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LSTVKFDVHGPLLESLNDRAHLGQELRTLPGT
HHEEEEECCCHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]