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The map label for this gene is yicI [C]

Identifier: 37519766

GI number: 37519766

Start: 186607

End: 188937

Strand: Reverse

Name: yicI [C]

Synonym: gll0197

Alternate gene names: 37519766

Gene position: 188937-186607 (Counterclockwise)

Preceding gene: 37519767

Following gene: 37519764

Centisome position: 4.06

GC content: 63.96

Gene sequence:

>2331_bases
ATGCCGCAGTACTTTGGCAAGTTACCCACCAACGGTGCTCCCTGGTCTGTTCTCGCCAACGTGTGCGACCTGGAGCGCGA
CGGGCGGGGGATTACCGTCGATTGTGGTGGACCGAAGTTGCGCGTCGGCGTGCTGGCTCCCAATCTGGTCCGCGTGCGCC
TGACGCCGACGGGCGCATTTTTTCCGCAGCGCTCCTGGGCGGCAAGTAAGGAGGACAGCGCGTGGCCCGAAACAGAATTT
TCAATGCACCAGCGCGCAGGGAGTATCGAGATTGCCACCGAGCACCTGCGGGTGGTCGTAGAAAGTGAGCCTTGCCGCAT
TGCCTGCTACGACCGCCAGGAGCGCCCCTTTGCCTGTGATAGTGCGCCTGCGATGGGCTGGCATACCGGTGCGGTTGCCG
CGTGGAAAGCGATCGAAGCCGGAGAGCACTTCTACGGCTTCGGCGAGCGCACCGGCCTACTCGATAAACTCTCCCAGCGC
AAAACCAACTGGACAAGCGACGCCCTCGACTACGGCTCGCTCACCGACGCGATGTACCAGGCGATCCCGTTTTATATCGC
GCTGCGGCCGGGGCTGGCCTATGGCGTCTACTTCAACACCACTTTTCACAGCCACTTCGATCTGGGCGGCGACGAGCCGG
GGCGGTTGCGTCTGGAGACCCAGGGTCCAGAGCTGGATTATTACCTCATCTACGGTCCCACCCCGGCCGAGGTGCTGGCC
ACCTACACCGAACTGACCGGAAAAATGGAATTGCCGCCCATCTGGGCCTTGGGCTATCACCAGTGCCGCTGGAGCTACGG
CAGCGAAGCCGAGGTGCGCGAGCTGGCCTATGAATTTCGCAGCCGCCGGATCCCCTGCGACGTCATTCACCTGGATATCG
ACTATATGCGCGGCTACCGCGTCTTTACCTGGAGCCCGAAACGCTTTGCAGATCCGTCCGGTCTGATCGCGGATCTGGCG
GATCAGGGCTTTCGAACCGTCGCCATCGTCGATCCGGGTGTGAAGTACGAACTGGATGCGGGCTACGCCGTCTTCGAGGA
GGGCCTGCAAAAAGACTATTTCGTGCGCCAGGCGGACGGACGGCTCTTTCACGGGTACGTCTGGCCCGACAAGGCCGTCT
TTCCGGATTTTATGCGCGCCGAGGTGCGCGCGTGGTGGGGCAGTTGGCACAAACAGCTCACCGAAATGGGCGTCGCCGGC
ATCTGGAACGATATGAACGAACCGGCCATCGACGATCGCCCCTTCGGCGACAGCGGCAACAAAATCAGCTTTCCCCTCGA
TGCGCCCCAGGGCGATCTCGCCGAGCGCACCACCCACGCCGAGACCCACAACCTCTACGGACAGATGATGGTGCGCGCCT
GCCGCGAGGCGATGGCGCGCCTGCGGCCTGCCGAGCGTTCTTTTGTGCTCACCCGGGCGGGCTTCGCCGGGGTGCAGCGC
CACGCCGCAGTCTGGATGGGGGACAACCAGTCGCAGTGGGAGCATCTGGAGATGTCGCTGCCGATGCTCCTCAACATGGG
CCTGTCGGGGGTAGCCTTCGTGGGGGCCGACATCGGCGGCTTTGCCGAGAACGCGACGGCGGAACTGTTTACCCGCTGGA
TGCAGGTGGGCATCCTCTATCCGCTGATGCGCGCCCACTCGGCCCTCGGCACCGCCCGCCACGAACCCTGGGTCTTTGGC
GAGCGGGTCGAAAATATCTGCCGCGAGTACATCGAACTGCGCTACCGGTTATTGCCCTATCTCTATTCGCTGTTTTGGCG
CGCATCAACGGCAGGGGAGCCCGTCCTGAGACCACTTCTCTACCACTATCCCGACGACGAGCGCACCTACCATCTGCACG
ATCAGGTCATGCTCGGTCCTGCACTGATGGCCGCCCCGGTGCTGCGGCCCGGGGTCGATTGCCGGGCGGTCTACCTGCCA
GGGGGCACCTGGTACGACTGGTGGAGCGGCAAAGGCCATACGGGGCCTGGCTGGATCCTCGCCCCGGCCTCCCTCGAACG
GCTGCCGCTTTTTGTACGGGCGGGGGCCGCCATCCCGATGGCACCGGTGAGGCAACACACCGGCGACTGGCCACCCACCG
GCCTGATCTGGCGCGTCTTTCCCGGCCATGGTACCGGCACACTCTACGAGGACGACGGACACAGCTTTGCCTACCGGAAG
CACCAGTGGACGCTCACCACCGTCCGAGTCGAGGGCACCCGCGTCACCTTCGACGAACGCCACGGCGACCACCCCAGGCC
CGACCGCGACGTCCAAGTCGAACTGGTCGGCCGGGGAACACAGTCGTTTCACGACGATGGTTCGGCGCGGCAATTGCAAT
TTGATCCATAA

Upstream 100 bases:

>100_bases
TGTCTGGCCAACACAGAAGAAGATCGCTCCCAGGGTGGAAAGTCCGGCGACTCCTCGCGTTGTAGAACTAGATGCTGTGA
CTTCACCCAAAGCGAGTGTC

Downstream 100 bases:

>100_bases
CTCAAAAAAGTGCTCTGTGAACAGTTTGCCCAACGATGATCCGACTAGCTGGACATTGACGATGGAGAAACTTCGAATCA
GACGGATCAATCCTCGTTGG

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MPQYFGKLPTNGAPWSVLANVCDLERDGRGITVDCGGPKLRVGVLAPNLVRVRLTPTGAFFPQRSWAASKEDSAWPETEF
SMHQRAGSIEIATEHLRVVVESEPCRIACYDRQERPFACDSAPAMGWHTGAVAAWKAIEAGEHFYGFGERTGLLDKLSQR
KTNWTSDALDYGSLTDAMYQAIPFYIALRPGLAYGVYFNTTFHSHFDLGGDEPGRLRLETQGPELDYYLIYGPTPAEVLA
TYTELTGKMELPPIWALGYHQCRWSYGSEAEVRELAYEFRSRRIPCDVIHLDIDYMRGYRVFTWSPKRFADPSGLIADLA
DQGFRTVAIVDPGVKYELDAGYAVFEEGLQKDYFVRQADGRLFHGYVWPDKAVFPDFMRAEVRAWWGSWHKQLTEMGVAG
IWNDMNEPAIDDRPFGDSGNKISFPLDAPQGDLAERTTHAETHNLYGQMMVRACREAMARLRPAERSFVLTRAGFAGVQR
HAAVWMGDNQSQWEHLEMSLPMLLNMGLSGVAFVGADIGGFAENATAELFTRWMQVGILYPLMRAHSALGTARHEPWVFG
ERVENICREYIELRYRLLPYLYSLFWRASTAGEPVLRPLLYHYPDDERTYHLHDQVMLGPALMAAPVLRPGVDCRAVYLP
GGTWYDWWSGKGHTGPGWILAPASLERLPLFVRAGAAIPMAPVRQHTGDWPPTGLIWRVFPGHGTGTLYEDDGHSFAYRK
HQWTLTTVRVEGTRVTFDERHGDHPRPDRDVQVELVGRGTQSFHDDGSARQLQFDP

Sequences:

>Translated_776_residues
MPQYFGKLPTNGAPWSVLANVCDLERDGRGITVDCGGPKLRVGVLAPNLVRVRLTPTGAFFPQRSWAASKEDSAWPETEF
SMHQRAGSIEIATEHLRVVVESEPCRIACYDRQERPFACDSAPAMGWHTGAVAAWKAIEAGEHFYGFGERTGLLDKLSQR
KTNWTSDALDYGSLTDAMYQAIPFYIALRPGLAYGVYFNTTFHSHFDLGGDEPGRLRLETQGPELDYYLIYGPTPAEVLA
TYTELTGKMELPPIWALGYHQCRWSYGSEAEVRELAYEFRSRRIPCDVIHLDIDYMRGYRVFTWSPKRFADPSGLIADLA
DQGFRTVAIVDPGVKYELDAGYAVFEEGLQKDYFVRQADGRLFHGYVWPDKAVFPDFMRAEVRAWWGSWHKQLTEMGVAG
IWNDMNEPAIDDRPFGDSGNKISFPLDAPQGDLAERTTHAETHNLYGQMMVRACREAMARLRPAERSFVLTRAGFAGVQR
HAAVWMGDNQSQWEHLEMSLPMLLNMGLSGVAFVGADIGGFAENATAELFTRWMQVGILYPLMRAHSALGTARHEPWVFG
ERVENICREYIELRYRLLPYLYSLFWRASTAGEPVLRPLLYHYPDDERTYHLHDQVMLGPALMAAPVLRPGVDCRAVYLP
GGTWYDWWSGKGHTGPGWILAPASLERLPLFVRAGAAIPMAPVRQHTGDWPPTGLIWRVFPGHGTGTLYEDDGHSFAYRK
HQWTLTTVRVEGTRVTFDERHGDHPRPDRDVQVELVGRGTQSFHDDGSARQLQFDP
>Mature_775_residues
PQYFGKLPTNGAPWSVLANVCDLERDGRGITVDCGGPKLRVGVLAPNLVRVRLTPTGAFFPQRSWAASKEDSAWPETEFS
MHQRAGSIEIATEHLRVVVESEPCRIACYDRQERPFACDSAPAMGWHTGAVAAWKAIEAGEHFYGFGERTGLLDKLSQRK
TNWTSDALDYGSLTDAMYQAIPFYIALRPGLAYGVYFNTTFHSHFDLGGDEPGRLRLETQGPELDYYLIYGPTPAEVLAT
YTELTGKMELPPIWALGYHQCRWSYGSEAEVRELAYEFRSRRIPCDVIHLDIDYMRGYRVFTWSPKRFADPSGLIADLAD
QGFRTVAIVDPGVKYELDAGYAVFEEGLQKDYFVRQADGRLFHGYVWPDKAVFPDFMRAEVRAWWGSWHKQLTEMGVAGI
WNDMNEPAIDDRPFGDSGNKISFPLDAPQGDLAERTTHAETHNLYGQMMVRACREAMARLRPAERSFVLTRAGFAGVQRH
AAVWMGDNQSQWEHLEMSLPMLLNMGLSGVAFVGADIGGFAENATAELFTRWMQVGILYPLMRAHSALGTARHEPWVFGE
RVENICREYIELRYRLLPYLYSLFWRASTAGEPVLRPLLYHYPDDERTYHLHDQVMLGPALMAAPVLRPGVDCRAVYLPG
GTWYDWWSGKGHTGPGWILAPASLERLPLFVRAGAAIPMAPVRQHTGDWPPTGLIWRVFPGHGTGTLYEDDGHSFAYRKH
QWTLTTVRVEGTRVTFDERHGDHPRPDRDVQVELVGRGTQSFHDDGSARQLQFDP

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=619, Percent_Identity=36.3489499192246, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI38202257, Length=619, Percent_Identity=36.3489499192246, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI66346737, Length=577, Percent_Identity=35.1819757365685, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI119393895, Length=614, Percent_Identity=34.3648208469055, Blast_Score=308, Evalue=9e-84,
Organism=Homo sapiens, GI119393893, Length=614, Percent_Identity=34.3648208469055, Blast_Score=308, Evalue=9e-84,
Organism=Homo sapiens, GI119393891, Length=614, Percent_Identity=34.3648208469055, Blast_Score=308, Evalue=9e-84,
Organism=Homo sapiens, GI221316699, Length=711, Percent_Identity=30.8016877637131, Blast_Score=301, Evalue=1e-81,
Organism=Homo sapiens, GI157364974, Length=619, Percent_Identity=31.6639741518578, Blast_Score=287, Evalue=3e-77,
Organism=Homo sapiens, GI310115361, Length=528, Percent_Identity=32.0075757575758, Blast_Score=264, Evalue=3e-70,
Organism=Homo sapiens, GI153791946, Length=372, Percent_Identity=27.4193548387097, Blast_Score=101, Evalue=3e-21,
Organism=Escherichia coli, GI2367256, Length=554, Percent_Identity=28.8808664259928, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI2367323, Length=384, Percent_Identity=25.5208333333333, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71991189, Length=582, Percent_Identity=35.3951890034364, Blast_Score=351, Evalue=7e-97,
Organism=Caenorhabditis elegans, GI17560798, Length=518, Percent_Identity=35.7142857142857, Blast_Score=333, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17560800, Length=518, Percent_Identity=35.7142857142857, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI71985706, Length=609, Percent_Identity=30.7060755336617, Blast_Score=245, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI32563849, Length=699, Percent_Identity=29.1845493562232, Blast_Score=240, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6319706, Length=553, Percent_Identity=32.1880650994575, Blast_Score=310, Evalue=7e-85,
Organism=Drosophila melanogaster, GI24643749, Length=512, Percent_Identity=35.15625, Blast_Score=331, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24643753, Length=512, Percent_Identity=35.15625, Blast_Score=331, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24643751, Length=512, Percent_Identity=35.15625, Blast_Score=331, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24643746, Length=512, Percent_Identity=35.15625, Blast_Score=331, Evalue=1e-90,
Organism=Drosophila melanogaster, GI21357605, Length=512, Percent_Identity=35.15625, Blast_Score=331, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24650054, Length=447, Percent_Identity=27.2930648769575, Blast_Score=139, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 87669; Mature: 87538

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQYFGKLPTNGAPWSVLANVCDLERDGRGITVDCGGPKLRVGVLAPNLVRVRLTPTGAF
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCCC
FPQRSWAASKEDSAWPETEFSMHQRAGSIEIATEHLRVVVESEPCRIACYDRQERPFACD
CCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEEEEECCCCEEEEECCCCCCCCCC
SAPAMGWHTGAVAAWKAIEAGEHFYGFGERTGLLDKLSQRKTNWTSDALDYGSLTDAMYQ
CCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHHCCCCCCHHCCCCHHHHHHHH
AIPFYIALRPGLAYGVYFNTTFHSHFDLGGDEPGRLRLETQGPELDYYLIYGPTPAEVLA
HCCEEEEECCCCEEEEEEECEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHH
TYTELTGKMELPPIWALGYHQCRWSYGSEAEVRELAYEFRSRRIPCDVIHLDIDYMRGYR
HHHHHCCCCCCCEEEECCCHHEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHCCEE
VFTWSPKRFADPSGLIADLADQGFRTVAIVDPGVKYELDAGYAVFEEGLQKDYFVRQADG
EEEECCHHHCCCCCHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHCCCCCCEEEECCC
RLFHGYVWPDKAVFPDFMRAEVRAWWGSWHKQLTEMGVAGIWNDMNEPAIDDRPFGDSGN
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCC
KISFPLDAPQGDLAERTTHAETHNLYGQMMVRACREAMARLRPAERSFVLTRAGFAGVQR
EEEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
HAAVWMGDNQSQWEHLEMSLPMLLNMGLSGVAFVGADIGGFAENATAELFTRWMQVGILY
CEEEEECCCCCHHHHHHHCCHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
PLMRAHSALGTARHEPWVFGERVENICREYIELRYRLLPYLYSLFWRASTAGEPVLRPLL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YHYPDDERTYHLHDQVMLGPALMAAPVLRPGVDCRAVYLPGGTWYDWWSGKGHTGPGWIL
HCCCCCCCEEEECCCEEECHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCCCCEEE
APASLERLPLFVRAGAAIPMAPVRQHTGDWPPTGLIWRVFPGHGTGTLYEDDGHSFAYRK
CCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCEEECCCCEEEEEE
HQWTLTTVRVEGTRVTFDERHGDHPRPDRDVQVELVGRGTQSFHDDGSARQLQFDP
EEEEEEEEEEECEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCC
>Mature Secondary Structure 
PQYFGKLPTNGAPWSVLANVCDLERDGRGITVDCGGPKLRVGVLAPNLVRVRLTPTGAF
CCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCEEEEEECCCCCC
FPQRSWAASKEDSAWPETEFSMHQRAGSIEIATEHLRVVVESEPCRIACYDRQERPFACD
CCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEEEEECCCCEEEEECCCCCCCCCC
SAPAMGWHTGAVAAWKAIEAGEHFYGFGERTGLLDKLSQRKTNWTSDALDYGSLTDAMYQ
CCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCHHHHHHHHCCCCCCHHCCCCHHHHHHHH
AIPFYIALRPGLAYGVYFNTTFHSHFDLGGDEPGRLRLETQGPELDYYLIYGPTPAEVLA
HCCEEEEECCCCEEEEEEECEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHH
TYTELTGKMELPPIWALGYHQCRWSYGSEAEVRELAYEFRSRRIPCDVIHLDIDYMRGYR
HHHHHCCCCCCCEEEECCCHHEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHCCEE
VFTWSPKRFADPSGLIADLADQGFRTVAIVDPGVKYELDAGYAVFEEGLQKDYFVRQADG
EEEECCHHHCCCCCHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHCCCCCCEEEECCC
RLFHGYVWPDKAVFPDFMRAEVRAWWGSWHKQLTEMGVAGIWNDMNEPAIDDRPFGDSGN
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCC
KISFPLDAPQGDLAERTTHAETHNLYGQMMVRACREAMARLRPAERSFVLTRAGFAGVQR
EEEECCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
HAAVWMGDNQSQWEHLEMSLPMLLNMGLSGVAFVGADIGGFAENATAELFTRWMQVGILY
CEEEEECCCCCHHHHHHHCCHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
PLMRAHSALGTARHEPWVFGERVENICREYIELRYRLLPYLYSLFWRASTAGEPVLRPLL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YHYPDDERTYHLHDQVMLGPALMAAPVLRPGVDCRAVYLPGGTWYDWWSGKGHTGPGWIL
HCCCCCCCEEEECCCEEECHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCCCCCEEE
APASLERLPLFVRAGAAIPMAPVRQHTGDWPPTGLIWRVFPGHGTGTLYEDDGHSFAYRK
CCCCCCCCEEEEECCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCEEECCCCEEEEEE
HQWTLTTVRVEGTRVTFDERHGDHPRPDRDVQVELVGRGTQSFHDDGSARQLQFDP
EEEEEEEEEEECEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]