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The map label for this gene is luxE [H]

Identifier: 34499773

GI number: 34499773

Start: 4658122

End: 4659252

Strand: Direct

Name: luxE [H]

Synonym: CV_4318

Alternate gene names: 34499773

Gene position: 4658122-4659252 (Clockwise)

Preceding gene: 34499772

Following gene: 34499774

Centisome position: 98.04

GC content: 69.5

Gene sequence:

>1131_bases
ATGACCACGCTTTCCCATGTCGAGGCGCTGTGCGCGCTGGAACAACCGTACCGCGCCGACGCCGAATGCGACCGCCTGTT
CGACGCCGCGATGCGCGAACTGGTCGACTACCACTGCGAGCACAGCCCCGGCTACCGCCGCTGGCTGGAGCAGAACGGCT
TCACGCCGGAACGGCTGGCCGGCCTGTCCGACTGGTCGCAGCTGCCGCCGATCTTCGCCAACTACTTCAAGCGCAGGCTG
CTGCTGAGCACGAGCGGCGAGGACGCGCTGGAGCTGACCTCGTCCGGCACCACCGGCCAGAAGAGCCGGATGCGTTACGA
CGAACGCAGCATCGGCGCCGCCCAGCGCATGGTGGACCGCATCTTCGACCACTACGGCTGGAACACGCCGCAGCAGCCGT
GCAACTACCTGCTGCTCAGCTACGAGCCGGCCGGCGCCATCACGCTCGGCACCGCCTACACCGACCAGTTCCTGTGCAAG
TACGCGCCGGTGAAGCGCGCCGTCTACGCGCTGCGCCACAACGGCAAGGGCAACGAGTTCGACCCGTTCGGCGCGATACG
CGCGCTGCAGGAATTCGCCGCGGAAGGCCTGCCGGTGCGCATCTTCGGTTTCCCCGCCTTCCTGTGGTTCGCGCTGGAGC
GGATGCGCGACATGGGCCTGCCGCCGCTCGCCCTGCACCCGGAATCGCTGGTCTTTCTCGGCGGCGGCTGGAAAACCCAC
GCCGACCAGGCCATCCCCAAGGCAGAGCTTTACCGCCGGCTGGGCGAGCAGCTGGGCCTGCCCGACGCCCGCTGCCGCGA
CGGCTACGGCTCGGTCGAGCACCCGGTGCCCTACGTCGAGTGCACCAACCACCGCTTCCACGTACCCAGCTGGGCGCGCG
CCTGGGCGCGCGACACCGCGACGCTGGCGCGGCTGCCCTATGGCGAGGCCGGCTTCCTGCACCTGGTTTCGCCCTACATC
ACCTCCAGCCCGGCGCACAGCATGCTGCTGAGCGACCTGGCGGTGCTGCAGCTGGCCGAACGCTGCGGCTGCGGCCTGGC
CACCGACTGGTTCGAGCTCTTGGGCCGCGCCGGCACCAGCAAGAGCCGCAGCTGCGCGATGGCCGCGTCCGAACTGATCA
AGGAGTCCTGA

Upstream 100 bases:

>100_bases
CCTCGCTGCTGGCCTTGCCGCCCTTGTGGATGCTGCTGCGCCGCCCGCGGCCCGAGCCCGTCGCCGCCTGACGCCCGTTT
TCTTCATCACTGGAACCGCC

Downstream 100 bases:

>100_bases
CATGTATCTGATTGATGGAGAACTGCGCGCCGACCTCGAGCTCGACGCGGCATTGGCCGCGCTGCGCGGCCGCCTGCCCG
ACGCGCTGGCTGCGGAGCCG

Product: long-chain-fatty-acid--luciferin-component ligase, Acyl-protein synthase

Products: NA

Alternate protein names: Acyl-protein synthetase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTTLSHVEALCALEQPYRADAECDRLFDAAMRELVDYHCEHSPGYRRWLEQNGFTPERLAGLSDWSQLPPIFANYFKRRL
LLSTSGEDALELTSSGTTGQKSRMRYDERSIGAAQRMVDRIFDHYGWNTPQQPCNYLLLSYEPAGAITLGTAYTDQFLCK
YAPVKRAVYALRHNGKGNEFDPFGAIRALQEFAAEGLPVRIFGFPAFLWFALERMRDMGLPPLALHPESLVFLGGGWKTH
ADQAIPKAELYRRLGEQLGLPDARCRDGYGSVEHPVPYVECTNHRFHVPSWARAWARDTATLARLPYGEAGFLHLVSPYI
TSSPAHSMLLSDLAVLQLAERCGCGLATDWFELLGRAGTSKSRSCAMAASELIKES

Sequences:

>Translated_376_residues
MTTLSHVEALCALEQPYRADAECDRLFDAAMRELVDYHCEHSPGYRRWLEQNGFTPERLAGLSDWSQLPPIFANYFKRRL
LLSTSGEDALELTSSGTTGQKSRMRYDERSIGAAQRMVDRIFDHYGWNTPQQPCNYLLLSYEPAGAITLGTAYTDQFLCK
YAPVKRAVYALRHNGKGNEFDPFGAIRALQEFAAEGLPVRIFGFPAFLWFALERMRDMGLPPLALHPESLVFLGGGWKTH
ADQAIPKAELYRRLGEQLGLPDARCRDGYGSVEHPVPYVECTNHRFHVPSWARAWARDTATLARLPYGEAGFLHLVSPYI
TSSPAHSMLLSDLAVLQLAERCGCGLATDWFELLGRAGTSKSRSCAMAASELIKES
>Mature_375_residues
TTLSHVEALCALEQPYRADAECDRLFDAAMRELVDYHCEHSPGYRRWLEQNGFTPERLAGLSDWSQLPPIFANYFKRRLL
LSTSGEDALELTSSGTTGQKSRMRYDERSIGAAQRMVDRIFDHYGWNTPQQPCNYLLLSYEPAGAITLGTAYTDQFLCKY
APVKRAVYALRHNGKGNEFDPFGAIRALQEFAAEGLPVRIFGFPAFLWFALERMRDMGLPPLALHPESLVFLGGGWKTHA
DQAIPKAELYRRLGEQLGLPDARCRDGYGSVEHPVPYVECTNHRFHVPSWARAWARDTATLARLPYGEAGFLHLVSPYIT
SSPAHSMLLSDLAVLQLAERCGCGLATDWFELLGRAGTSKSRSCAMAASELIKES

Specific function: Acyl-protein synthetase activates tetradecanoic acid. It is a component of the fatty acid reductase complex responsible for converting tetradecanoic acid to the aldehyde which serves as substrate in the luciferase-catalyzed reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016671
- InterPro:   IPR007534 [H]

Pfam domain/function: PF04443 LuxE [H]

EC number: =6.2.1.19 [H]

Molecular weight: Translated: 42118; Mature: 41987

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLSHVEALCALEQPYRADAECDRLFDAAMRELVDYHCEHSPGYRRWLEQNGFTPERLA
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHH
GLSDWSQLPPIFANYFKRRLLLSTSGEDALELTSSGTTGQKSRMRYDERSIGAAQRMVDR
CCCCHHHCCHHHHHHHHHHHHHCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
IFDHYGWNTPQQPCNYLLLSYEPAGAITLGTAYTDQFLCKYAPVKRAVYALRHNGKGNEF
HHHHCCCCCCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPFGAIRALQEFAAEGLPVRIFGFPAFLWFALERMRDMGLPPLALHPESLVFLGGGWKTH
CHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCC
ADQAIPKAELYRRLGEQLGLPDARCRDGYGSVEHPVPYVECTNHRFHVPSWARAWARDTA
HHHCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCEEECCCEEECCHHHHHHHHHHH
TLARLPYGEAGFLHLVSPYITSSPAHSMLLSDLAVLQLAERCGCGLATDWFELLGRAGTS
HHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
KSRSCAMAASELIKES
CCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLSHVEALCALEQPYRADAECDRLFDAAMRELVDYHCEHSPGYRRWLEQNGFTPERLA
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHH
GLSDWSQLPPIFANYFKRRLLLSTSGEDALELTSSGTTGQKSRMRYDERSIGAAQRMVDR
CCCCHHHCCHHHHHHHHHHHHHCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
IFDHYGWNTPQQPCNYLLLSYEPAGAITLGTAYTDQFLCKYAPVKRAVYALRHNGKGNEF
HHHHCCCCCCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPFGAIRALQEFAAEGLPVRIFGFPAFLWFALERMRDMGLPPLALHPESLVFLGGGWKTH
CHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCC
ADQAIPKAELYRRLGEQLGLPDARCRDGYGSVEHPVPYVECTNHRFHVPSWARAWARDTA
HHHCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCEEECCCEEECCHHHHHHHHHHH
TLARLPYGEAGFLHLVSPYITSSPAHSMLLSDLAVLQLAERCGCGLATDWFELLGRAGTS
HHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
KSRSCAMAASELIKES
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2775296; 2303459; 3514602 [H]