Click here to switch to the map view.

The map label for this gene is qseD [H]

Identifier: 34499568

GI number: 34499568

Start: 4453658

End: 4454566

Strand: Reverse

Name: qseD [H]

Synonym: CV_4113

Alternate gene names: 34499568

Gene position: 4454566-4453658 (Counterclockwise)

Preceding gene: 34499570

Following gene: 34499567

Centisome position: 93.76

GC content: 69.97

Gene sequence:

>909_bases
ATGGAAACCCGCTGGCTGGAAGACTTCCTGGTATTGGCCGACACCGGCAGCTTCACCCGCTCGGCCGAGCTGCGCCACCT
GACGCAGCCGGCGTTCTCGCGCCGCATCCGCGCCTTGGAGAGCTGGCTGGGCGCCGACCTGATAGACCGCACCACTTACC
CCACCAAGCTCACCGCCGCCGGCAAGCTGCTGCGCGAGCAGGCGGTGTCGCTGCTGGCCCAACTCAACACCACCCGCACC
ATGCTGCGCGGCCTGCAGCCCCTGCCGCAGGGCACGCTGGAATTCGCGGTGCCGCACACGTTGTCCTTCTCCTATTTTCC
CAAGTGGCTGACCGAGGTCGAGGCCGGCTTCGGCAAGCTGTCCTGCCGGCTGCAGGCCAGCAACGTCCACGACGCGGTGC
TGGCCTTCGTCGAAGGCGGCAGCGACCTCTTGATGTGCTACCACCATCCCAAGCAGCCGGTGGAGCTGCACGACGCGCGC
TACGGCGGCCTGCGGCTGGGCGTGGAGCGTCTGCGGCCGTACGCCGCGGCCGATGGCGGCGCGGCGCGCTACGCGCTGCC
GGGCTCCGCCGACGCGCCGCAGCCTTTCCTCGGCTACGCCAGCAACGCCTATTTCCGGCTGATGAGCGATTTGCTGCTGG
TCGGCGGCCCCGAGCCCGCCCACCTGTCGCTGCGCTACGAGACCGATATGGCCGAGGGCCTGAAGCAGATGGCGCTGGCC
GGCCACGGCCTCGCCTTCCTGCCGGAAAGCGCGGTGGCGGCGGAGTGCGAGGCTGGACGGCTGGCGGCGGCCGGCGGCGA
TGAATGGAGCGTGGAGATGGAGGTGAGGCTGTATTGCGACCACCGCCGCGGCCGCGCGGCGCTGGAAGACTTGTGGGATT
ACCTGGCCGAACGCTATCCGGCGGTGTAG

Upstream 100 bases:

>100_bases
AAACGGTTGGCGCGATGGGATATCCGAAGATAGATCGGCGCCGCGCCGGAAAGTGCCGCGCCGGTGTAACATCGGGCATC
CCGAATCTGGACGCGCGCCG

Downstream 100 bases:

>100_bases
CACCAAGCCGCGCCGGACAAGGCTGGCGCAAGGTTATGCATTTCCGGCATGACCCCATCGCCATTCGGAATTGGCCAAGC
TTCCGGGGCGGGCATACAGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
METRWLEDFLVLADTGSFTRSAELRHLTQPAFSRRIRALESWLGADLIDRTTYPTKLTAAGKLLREQAVSLLAQLNTTRT
MLRGLQPLPQGTLEFAVPHTLSFSYFPKWLTEVEAGFGKLSCRLQASNVHDAVLAFVEGGSDLLMCYHHPKQPVELHDAR
YGGLRLGVERLRPYAAADGGAARYALPGSADAPQPFLGYASNAYFRLMSDLLLVGGPEPAHLSLRYETDMAEGLKQMALA
GHGLAFLPESAVAAECEAGRLAAAGGDEWSVEMEVRLYCDHRRGRAALEDLWDYLAERYPAV

Sequences:

>Translated_302_residues
METRWLEDFLVLADTGSFTRSAELRHLTQPAFSRRIRALESWLGADLIDRTTYPTKLTAAGKLLREQAVSLLAQLNTTRT
MLRGLQPLPQGTLEFAVPHTLSFSYFPKWLTEVEAGFGKLSCRLQASNVHDAVLAFVEGGSDLLMCYHHPKQPVELHDAR
YGGLRLGVERLRPYAAADGGAARYALPGSADAPQPFLGYASNAYFRLMSDLLLVGGPEPAHLSLRYETDMAEGLKQMALA
GHGLAFLPESAVAAECEAGRLAAAGGDEWSVEMEVRLYCDHRRGRAALEDLWDYLAERYPAV
>Mature_302_residues
METRWLEDFLVLADTGSFTRSAELRHLTQPAFSRRIRALESWLGADLIDRTTYPTKLTAAGKLLREQAVSLLAQLNTTRT
MLRGLQPLPQGTLEFAVPHTLSFSYFPKWLTEVEAGFGKLSCRLQASNVHDAVLAFVEGGSDLLMCYHHPKQPVELHDAR
YGGLRLGVERLRPYAAADGGAARYALPGSADAPQPFLGYASNAYFRLMSDLLLVGGPEPAHLSLRYETDMAEGLKQMALA
GHGLAFLPESAVAAECEAGRLAAAGGDEWSVEMEVRLYCDHRRGRAALEDLWDYLAERYPAV

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=298, Percent_Identity=33.2214765100671, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI157672245, Length=125, Percent_Identity=33.6, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=138, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33295; Mature: 33295

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRWLEDFLVLADTGSFTRSAELRHLTQPAFSRRIRALESWLGADLIDRTTYPTKLTAA
CCCHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHH
GKLLREQAVSLLAQLNTTRTMLRGLQPLPQGTLEFAVPHTLSFSYFPKWLTEVEAGFGKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEE
SCRLQASNVHDAVLAFVEGGSDLLMCYHHPKQPVELHDARYGGLRLGVERLRPYAAADGG
EEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCC
AARYALPGSADAPQPFLGYASNAYFRLMSDLLLVGGPEPAHLSLRYETDMAEGLKQMALA
CEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
GHGLAFLPESAVAAECEAGRLAAAGGDEWSVEMEVRLYCDHRRGRAALEDLWDYLAERYP
CCCCEECCCCHHHHCCCCCCEEECCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCC
AV
CC
>Mature Secondary Structure
METRWLEDFLVLADTGSFTRSAELRHLTQPAFSRRIRALESWLGADLIDRTTYPTKLTAA
CCCHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHH
GKLLREQAVSLLAQLNTTRTMLRGLQPLPQGTLEFAVPHTLSFSYFPKWLTEVEAGFGKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEE
SCRLQASNVHDAVLAFVEGGSDLLMCYHHPKQPVELHDARYGGLRLGVERLRPYAAADGG
EEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCC
AARYALPGSADAPQPFLGYASNAYFRLMSDLLLVGGPEPAHLSLRYETDMAEGLKQMALA
CEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
GHGLAFLPESAVAAECEAGRLAAAGGDEWSVEMEVRLYCDHRRGRAALEDLWDYLAERYP
CCCCEECCCCHHHHCCCCCCEEECCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCC
AV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]