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The map label for this gene is 34499345

Identifier: 34499345

GI number: 34499345

Start: 4198134

End: 4199621

Strand: Reverse

Name: 34499345

Synonym: CV_3890

Alternate gene names: NA

Gene position: 4199621-4198134 (Counterclockwise)

Preceding gene: 34499346

Following gene: 34499344

Centisome position: 88.39

GC content: 63.98

Gene sequence:

>1488_bases
ATGAGCAAGCCGCTATTCATCTTCGAGATGGCCAACAACCACATGGGCAACGTCGAGCACGGCGTCGCGCTGATCCGCGC
CATCCGCGAATCCTGCCAGGGCTTCGATTTCGACTTCGGCTTCAAGCTGCAGTACCGCAACCTGGACACCTTCATCCATT
CCAGCTTCAAGGGCCGCGACGACGTCAAGTACGTGAAGCGTTTCGAGGAGACCCGGCTGCAGCCGGAACAGATGCAAAAG
CTGGTGGCCGAGATGAAGGCCAACGGCTTCAAGGCGATCTGCACCCCGTTCGACGAGGAATCGGTGGACCTGATCGAAGC
GCACGGCATCGAGATCATCAAGATCGCCAGTTGCTCGTTCACCGATTGGCCCCTGCTGGAGCGCATCGCCCGCAGCGACA
AGCCGGTGGTGGCGTCCACCGCCGGCGCGCGGCGCGAGGACATCGACAAGGTGGTCAGCTTCATGCTGCATCGCGGCAAG
GATCTGACCATCATGCACTGTGTGGCCGAGTACCCGACGCCGGACGACCATCTGCACCTGGCGCGGATCAAGACGTTGCG
CCAGCAGTACGCCGGCGTGCGCATCGGCTACTCCACCCACGAAGACCCGGACTTGATGGAACCCATCATGCTGGCGGTCG
CCCAGGGCGCGACGGTGTTCGAGAAGCATGTGGGCCTGCCCACCGACCAGTACGGCATCAACAATTACTCCGCCAATCCG
GAGCAGGTCCGCCGCTGGCTGGCCGCCGCCGCGCGCGCGCTGGCCATGCTGGGCGATGGCGAGGACGACGCGGTGTCGGA
GACCGAGCAAGCCAGCCTGCGCTCGCTGCGCCGCGGCGTGTTCGCCACCCGGCCGGTCGCGGCCGGCGAGGCGCTGACCG
CCGACAATGTCAGCTTCGCCTTCCCGCCGGTGGAAGGGCAACTGACCGCCAACGAATGGTCCAAATATGTCCGCTACACC
GCCAAGACGCCGATCGCCGCCGACGCGCCCGTGATGGCCGCCGATCTGGAGCCGGTGAACCTGCGCGACAAGGTGCAGAA
GGCGGTGGAGGCGGTGAAGGCCTTGTTCAAGCGCGGCAAGATCGTGGTGCCGGGCCGCTCCGAGCTGGAAATCTCCCACC
ATTACGGCATGGAGCATTTCCACGAATACGGCCTGACCATGGTGACCGTGGTCAACCGCGAATACTGCAAGAAGCTGATC
GTGATGCTGCCGGGCCAGACCCATCCGGAGCAGTACCACCACAAGAAGGAAGAAACCTTCATCGTGCTCTACGGCGAGAT
GACCATCTGGCTGGACGACGAGGAGCGCCAGGCCCAGGCCGGCGACGTGATCACCGTGCAGCGCGGCGTGCGCCACCGCT
TCCATTCGCGCAATGGCGTGGTGTTCGAGGAGATCTCGTCCACCCATTACGTCGACGATTCCTACTATACCGACGAGCGG
ATCAGCGCCAACCAGGACCGCAAGACCCGCCTGACCTACTGGATGTGA

Upstream 100 bases:

>100_bases
GGATCGGCCTCTATCCGGGCTTGAGCCGGGAGATGCTGGATTTCACCGTCGAGAAGCTGGAAACCTTCCTCGGCGCCAAC
TTCGACTAGAGAGGCCCATC

Downstream 100 bases:

>100_bases
GCATGAGCGCAAAACTTGTCCGCCTGGCGGACTACGTGATGGATTTCCTGGCCGCGCGCGGCGTGCGCCACGTGTTTCTG
CTGCCGGGCGGCGGCGCGAT

Product: spore coat polysaccharide biosynthesis protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSKPLFIFEMANNHMGNVEHGVALIRAIRESCQGFDFDFGFKLQYRNLDTFIHSSFKGRDDVKYVKRFEETRLQPEQMQK
LVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSFTDWPLLERIARSDKPVVASTAGARREDIDKVVSFMLHRGK
DLTIMHCVAEYPTPDDHLHLARIKTLRQQYAGVRIGYSTHEDPDLMEPIMLAVAQGATVFEKHVGLPTDQYGINNYSANP
EQVRRWLAAAARALAMLGDGEDDAVSETEQASLRSLRRGVFATRPVAAGEALTADNVSFAFPPVEGQLTANEWSKYVRYT
AKTPIAADAPVMAADLEPVNLRDKVQKAVEAVKALFKRGKIVVPGRSELEISHHYGMEHFHEYGLTMVTVVNREYCKKLI
VMLPGQTHPEQYHHKKEETFIVLYGEMTIWLDDEERQAQAGDVITVQRGVRHRFHSRNGVVFEEISSTHYVDDSYYTDER
ISANQDRKTRLTYWM

Sequences:

>Translated_495_residues
MSKPLFIFEMANNHMGNVEHGVALIRAIRESCQGFDFDFGFKLQYRNLDTFIHSSFKGRDDVKYVKRFEETRLQPEQMQK
LVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSFTDWPLLERIARSDKPVVASTAGARREDIDKVVSFMLHRGK
DLTIMHCVAEYPTPDDHLHLARIKTLRQQYAGVRIGYSTHEDPDLMEPIMLAVAQGATVFEKHVGLPTDQYGINNYSANP
EQVRRWLAAAARALAMLGDGEDDAVSETEQASLRSLRRGVFATRPVAAGEALTADNVSFAFPPVEGQLTANEWSKYVRYT
AKTPIAADAPVMAADLEPVNLRDKVQKAVEAVKALFKRGKIVVPGRSELEISHHYGMEHFHEYGLTMVTVVNREYCKKLI
VMLPGQTHPEQYHHKKEETFIVLYGEMTIWLDDEERQAQAGDVITVQRGVRHRFHSRNGVVFEEISSTHYVDDSYYTDER
ISANQDRKTRLTYWM
>Mature_494_residues
SKPLFIFEMANNHMGNVEHGVALIRAIRESCQGFDFDFGFKLQYRNLDTFIHSSFKGRDDVKYVKRFEETRLQPEQMQKL
VAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSFTDWPLLERIARSDKPVVASTAGARREDIDKVVSFMLHRGKD
LTIMHCVAEYPTPDDHLHLARIKTLRQQYAGVRIGYSTHEDPDLMEPIMLAVAQGATVFEKHVGLPTDQYGINNYSANPE
QVRRWLAAAARALAMLGDGEDDAVSETEQASLRSLRRGVFATRPVAAGEALTADNVSFAFPPVEGQLTANEWSKYVRYTA
KTPIAADAPVMAADLEPVNLRDKVQKAVEAVKALFKRGKIVVPGRSELEISHHYGMEHFHEYGLTMVTVVNREYCKKLIV
MLPGQTHPEQYHHKKEETFIVLYGEMTIWLDDEERQAQAGDVITVQRGVRHRFHSRNGVVFEEISSTHYVDDSYYTDERI
SANQDRKTRLTYWM

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=319, Percent_Identity=23.8244514106583, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21357081, Length=357, Percent_Identity=26.0504201680672, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 56274; Mature: 56142

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLFIFEMANNHMGNVEHGVALIRAIRESCQGFDFDFGFKLQYRNLDTFIHSSFKGRD
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCH
DVKYVKRFEETRLQPEQMQKLVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSF
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHCCEEEEEEECCCC
TDWPLLERIARSDKPVVASTAGARREDIDKVVSFMLHRGKDLTIMHCVAEYPTPDDHLHL
CCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHH
ARIKTLRQQYAGVRIGYSTHEDPDLMEPIMLAVAQGATVFEKHVGLPTDQYGINNYSANP
HHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCH
EQVRRWLAAAARALAMLGDGEDDAVSETEQASLRSLRRGVFATRPVAAGEALTADNVSFA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCEEE
FPPVEGQLTANEWSKYVRYTAKTPIAADAPVMAADLEPVNLRDKVQKAVEAVKALFKRGK
CCCCCCEEEHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
IVVPGRSELEISHHYGMEHFHEYGLTMVTVVNREYCKKLIVMLPGQTHPEQYHHKKEETF
EEECCCCCEEEHHHHCHHHHHHCCCEEEEHHCHHHHHHHHEECCCCCCCHHHHCCCCCEE
IVLYGEMTIWLDDEERQAQAGDVITVQRGVRHRFHSRNGVVFEEISSTHYVDDSYYTDER
EEEEEEEEEEECCHHHHHHCCCEEEEHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCC
ISANQDRKTRLTYWM
CCCCCCCCCEEEECC
>Mature Secondary Structure 
SKPLFIFEMANNHMGNVEHGVALIRAIRESCQGFDFDFGFKLQYRNLDTFIHSSFKGRD
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCH
DVKYVKRFEETRLQPEQMQKLVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSF
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHCCEEEEEEECCCC
TDWPLLERIARSDKPVVASTAGARREDIDKVVSFMLHRGKDLTIMHCVAEYPTPDDHLHL
CCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHH
ARIKTLRQQYAGVRIGYSTHEDPDLMEPIMLAVAQGATVFEKHVGLPTDQYGINNYSANP
HHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCH
EQVRRWLAAAARALAMLGDGEDDAVSETEQASLRSLRRGVFATRPVAAGEALTADNVSFA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCEEE
FPPVEGQLTANEWSKYVRYTAKTPIAADAPVMAADLEPVNLRDKVQKAVEAVKALFKRGK
CCCCCCEEEHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
IVVPGRSELEISHHYGMEHFHEYGLTMVTVVNREYCKKLIVMLPGQTHPEQYHHKKEETF
EEECCCCCEEEHHHHCHHHHHHCCCEEEEHHCHHHHHHHHEECCCCCCCHHHHCCCCCEE
IVLYGEMTIWLDDEERQAQAGDVITVQRGVRHRFHSRNGVVFEEISSTHYVDDSYYTDER
EEEEEEEEEEECCHHHHHHCCCEEEEHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCC
ISANQDRKTRLTYWM
CCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]