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The map label for this gene is xseA [H]

Identifier: 34499019

GI number: 34499019

Start: 3870572

End: 3871936

Strand: Direct

Name: xseA [H]

Synonym: CV_3564

Alternate gene names: 34499019

Gene position: 3870572-3871936 (Clockwise)

Preceding gene: 34499017

Following gene: 34499021

Centisome position: 81.47

GC content: 69.52

Gene sequence:

>1365_bases
TTGACAAGACACCATTTCCCTGATCAAAGCCAGGACGTGATCAGCGTCTCCTCGCTCAACCGCATGGCGCGGGACCTGCT
GGAAGCAGGCATTCCGCCGGTGTGGATCGGCGGGGAAATCTCCAATCTGACGCTGGCCGCCTCCGGCCACGCCTACTTCT
CGCTGAAGGACGGCGGCGCCCAGATCCGCTGCGTGATGTTCCGCCACAAGCTGTCCCTGCTGCCGTTCCGCCCGCAGGAA
GGCATGCAGGTGGAGCTGCGCGGCCAAGTGACGCTGTACGAGGCCAGGGGCGAATTCCAGATCAATGTCGGCGAGATGCG
CGCCGCCGGCCTCGGCAGGCTGTACGAGGCCTTCGAGCGGCTGAAGGCCCGGCTGCAGGCGGAGGGCCTGTTCGACAACG
CGCGCAAGCGCGAGCTGCCCGCCCATCCGGCGGCCATCGGCATCGTCACTTCGCCCGCCGCCGCCGCGCTACGCGACGTG
GTCAGCACGCTGCGCCGCCGCATGCCCGGCATCCCGCTGATTCTCTACCCGACCCAGGTGCAGGGAGAAGGCTCGGCCAG
GCAGATCGCCGACGCCCTCCGCCTGGCCGGCGAGCGGCGCGAGGTCGACGTGCTGATCGTCTGCCGTGGCGGCGGCAGCA
TCGAAGACCTGTGGTCGTTCAACGAGGAAATCGTCGCTCGCGCCGTCGCCGCCAGCCCCATCCCCACCGTCAGCGGCGTC
GGCCACGAAACCGATTTCACCATCTGCGACTTCGTCGCCGACCGCCGCGCGCCGACGCCGACCGCGGCGGCGGAACTGGT
ATCGCCCAACCGCGAGCACCTGGCCATCCAGCTGGAACAGACCAAGCGCGCGCTGGAGCGCGCCTTGAGCCGGCTATTGA
CGGACAAGACGCAGCAGCTGGACTTCCTCGGCCGCCGCCTGACGCATCCCGGCGCGCGCTTGCAGGTGCAGCGCGAACGG
CTGGACGCGTTGTCGAGCGCGCTTGGGCAGCGCGTCCAGGCTGCCTTCGAGCAAGGCCGCTGGCGGCTGCAACTGGCCGG
CACCCGCCTCTCCCGCCACCAACCCGATCTAGACGTGGGCAAGCAGGCGCTGCGGCAACGGCAGGCCGCGCTGCTGCGCG
CCCGCGACCGTCTGCTGGAGCGCCGCGCCCAGCAATTGGCGCAACTGGCCGCCACGCTGACCGCGCTCAACCCGGAAGCC
GTGCTGGCGCGTGGCTACGCTATCGTGCAGAAGCAGGATGGCCGCGCGGTCAAGAACCCGGCGGAATTGGCTGACCGCGA
AAAAGTGACGCTGCGGCTGGCCGAAGGCAGCGCCGAGGCGCGCATCGAGCACAATCAGGGCGCCCAGGGCCAGTTGCCGT
TTTAG

Upstream 100 bases:

>100_bases
ATTGATTTGATTGCATTTTGAATCAGATATCAAACACTACGCAGGTGGGAGGCCGCCTGCGCCCCTTGAATATTTACTCC
AGTGAAGCGCTGTGGATCAC

Downstream 100 bases:

>100_bases
CGCTGCGCAAAACCCCTGATGCTGCGTTGCGCCGACGCGTCGTACGATTTACACCGCCGGCGCGCCTTGCCTCAGGCGCT
TCACGGAGATCCGTTAGCGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTRHHFPDQSQDVISVSSLNRMARDLLEAGIPPVWIGGEISNLTLAASGHAYFSLKDGGAQIRCVMFRHKLSLLPFRPQE
GMQVELRGQVTLYEARGEFQINVGEMRAAGLGRLYEAFERLKARLQAEGLFDNARKRELPAHPAAIGIVTSPAAAALRDV
VSTLRRRMPGIPLILYPTQVQGEGSARQIADALRLAGERREVDVLIVCRGGGSIEDLWSFNEEIVARAVAASPIPTVSGV
GHETDFTICDFVADRRAPTPTAAAELVSPNREHLAIQLEQTKRALERALSRLLTDKTQQLDFLGRRLTHPGARLQVQRER
LDALSSALGQRVQAAFEQGRWRLQLAGTRLSRHQPDLDVGKQALRQRQAALLRARDRLLERRAQQLAQLAATLTALNPEA
VLARGYAIVQKQDGRAVKNPAELADREKVTLRLAEGSAEARIEHNQGAQGQLPF

Sequences:

>Translated_454_residues
MTRHHFPDQSQDVISVSSLNRMARDLLEAGIPPVWIGGEISNLTLAASGHAYFSLKDGGAQIRCVMFRHKLSLLPFRPQE
GMQVELRGQVTLYEARGEFQINVGEMRAAGLGRLYEAFERLKARLQAEGLFDNARKRELPAHPAAIGIVTSPAAAALRDV
VSTLRRRMPGIPLILYPTQVQGEGSARQIADALRLAGERREVDVLIVCRGGGSIEDLWSFNEEIVARAVAASPIPTVSGV
GHETDFTICDFVADRRAPTPTAAAELVSPNREHLAIQLEQTKRALERALSRLLTDKTQQLDFLGRRLTHPGARLQVQRER
LDALSSALGQRVQAAFEQGRWRLQLAGTRLSRHQPDLDVGKQALRQRQAALLRARDRLLERRAQQLAQLAATLTALNPEA
VLARGYAIVQKQDGRAVKNPAELADREKVTLRLAEGSAEARIEHNQGAQGQLPF
>Mature_453_residues
TRHHFPDQSQDVISVSSLNRMARDLLEAGIPPVWIGGEISNLTLAASGHAYFSLKDGGAQIRCVMFRHKLSLLPFRPQEG
MQVELRGQVTLYEARGEFQINVGEMRAAGLGRLYEAFERLKARLQAEGLFDNARKRELPAHPAAIGIVTSPAAAALRDVV
STLRRRMPGIPLILYPTQVQGEGSARQIADALRLAGERREVDVLIVCRGGGSIEDLWSFNEEIVARAVAASPIPTVSGVG
HETDFTICDFVADRRAPTPTAAAELVSPNREHLAIQLEQTKRALERALSRLLTDKTQQLDFLGRRLTHPGARLQVQRERL
DALSSALGQRVQAAFEQGRWRLQLAGTRLSRHQPDLDVGKQALRQRQAALLRARDRLLERRAQQLAQLAATLTALNPEAV
LARGYAIVQKQDGRAVKNPAELADREKVTLRLAEGSAEARIEHNQGAQGQLPF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=448, Percent_Identity=43.9732142857143, Blast_Score=352, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50079; Mature: 49948

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHHFPDQSQDVISVSSLNRMARDLLEAGIPPVWIGGEISNLTLAASGHAYFSLKDGGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCEEEEEECCCC
QIRCVMFRHKLSLLPFRPQEGMQVELRGQVTLYEARGEFQINVGEMRAAGLGRLYEAFER
EEEEEEEEHHHHCCCCCCCCCCEEEEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHH
LKARLQAEGLFDNARKRELPAHPAAIGIVTSPAAAALRDVVSTLRRRMPGIPLILYPTQV
HHHHHHHCCCHHCHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCC
QGEGSARQIADALRLAGERREVDVLIVCRGGGSIEDLWSFNEEIVARAVAASPIPTVSGV
CCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCC
GHETDFTICDFVADRRAPTPTAAAELVSPNREHLAIQLEQTKRALERALSRLLTDKTQQL
CCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHH
DFLGRRLTHPGARLQVQRERLDALSSALGQRVQAAFEQGRWRLQLAGTRLSRHQPDLDVG
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCCCHHHH
KQALRQRQAALLRARDRLLERRAQQLAQLAATLTALNPEAVLARGYAIVQKQDGRAVKNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCCCCCH
AELADREKVTLRLAEGSAEARIEHNQGAQGQLPF
HHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
TRHHFPDQSQDVISVSSLNRMARDLLEAGIPPVWIGGEISNLTLAASGHAYFSLKDGGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCEEEEEECCCC
QIRCVMFRHKLSLLPFRPQEGMQVELRGQVTLYEARGEFQINVGEMRAAGLGRLYEAFER
EEEEEEEEHHHHCCCCCCCCCCEEEEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHH
LKARLQAEGLFDNARKRELPAHPAAIGIVTSPAAAALRDVVSTLRRRMPGIPLILYPTQV
HHHHHHHCCCHHCHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCC
QGEGSARQIADALRLAGERREVDVLIVCRGGGSIEDLWSFNEEIVARAVAASPIPTVSGV
CCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCC
GHETDFTICDFVADRRAPTPTAAAELVSPNREHLAIQLEQTKRALERALSRLLTDKTQQL
CCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHH
DFLGRRLTHPGARLQVQRERLDALSSALGQRVQAAFEQGRWRLQLAGTRLSRHQPDLDVG
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHCCCCCHHHH
KQALRQRQAALLRARDRLLERRAQQLAQLAATLTALNPEAVLARGYAIVQKQDGRAVKNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCCCCCH
AELADREKVTLRLAEGSAEARIEHNQGAQGQLPF
HHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA