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The map label for this gene is hflC [H]

Identifier: 34498985

GI number: 34498985

Start: 3838265

End: 3839149

Strand: Reverse

Name: hflC [H]

Synonym: CV_3530

Alternate gene names: 34498985

Gene position: 3839149-3838265 (Counterclockwise)

Preceding gene: 34498986

Following gene: 34498984

Centisome position: 80.81

GC content: 62.26

Gene sequence:

>885_bases
ATGACTGAAAGACTGATTCCCACCCTGGCGGCGGTGGTCGGCGCGCTGTTCGTCGCCAGCCTGTCGCTGTTTACCGTCGA
TCAGCGCCAGTACGCGCTGGTTTTCCAGTTCGGCGAAGTCGTGAAGGTGATCTCCGAGCCGGGCATCCAGTTCAAGATTC
CGTTGCTGCAGAACGTCCGCTATTTCGACCGCCGCGTGCAGACCATAGACGCCGAGGCGCCTGAGCTGTTCAACACCCGC
GAGAAGAAAAACGTGCTGGTGGACAGCTTCGTGAAGTGGCGTGTTGTGGATGTGTCACAGTTCTACAAGAGCGTCGGCTC
CGAGGCCGCCGCGGTGGCGCGGCTGAAGCAGACCATCAACGACGGCCTGCGCGCCGAGTTCGGCCAGAAGACCGTCGCGG
ACGTCATTTCCGGCCAGCGCGACCAGGTGATGGAGACGGTTCGCAAGCGCGCGGACGCGGATGCGCGTAAAATAGGCGTG
GAAATTCTCGACGTGCGCTTAAAACGAGTCGATTTTCCGGATAAAATAAGCAGTTCCGTCTACGACCGCATGCAGTCCGA
GCGCCGCACCGTGGCCAGCCAGCTGCGCAGCGAGGGCGCGGCCGACGCCGAACGCGTGCGGGCCGAAGCCGACAAGCAGC
GCGACGTGATCCTGGCCGAAGCCTACCGCAAGGCGCAGGCGCTGAAGGGCGCGGGCGACGCCAAGGCGGCGGCGATCTAT
GCCGAGGCCTATGGCAAGAACCCCGAGTTCTACGCCTTCTGGCGCAGCATGGAGGCGTACAAAGAGTCGTTCAAGAACAA
GAGCGACGTGATGGTGCTCGACCCAAGCAGCGACTTCTTCAAGTATCTGAAGAATCCGCAGGCGGGGCAGGGCAAGAGCA
AGTAG

Upstream 100 bases:

>100_bases
CAACCCCGGCTCCGGAGGCTGCGGCCCAGCCGGCTTCGCCGCCGGCGGCGAAGAACGGGCGCGACGCGTCGCGCGGTCGT
GATTTCTTTGGAGCGGAGCG

Downstream 100 bases:

>100_bases
GCGACAATTGATTTTTTGAGAAGACTGGCCGGGGCGACCTGGCCAGTTTGCTGATGACAAGGCGGGTCCTTCCCCGCCTT
TTATTCTGTTGAAACGAAAT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTERLIPTLAAVVGALFVASLSLFTVDQRQYALVFQFGEVVKVISEPGIQFKIPLLQNVRYFDRRVQTIDAEAPELFNTR
EKKNVLVDSFVKWRVVDVSQFYKSVGSEAAAVARLKQTINDGLRAEFGQKTVADVISGQRDQVMETVRKRADADARKIGV
EILDVRLKRVDFPDKISSSVYDRMQSERRTVASQLRSEGAADAERVRAEADKQRDVILAEAYRKAQALKGAGDAKAAAIY
AEAYGKNPEFYAFWRSMEAYKESFKNKSDVMVLDPSSDFFKYLKNPQAGQGKSK

Sequences:

>Translated_294_residues
MTERLIPTLAAVVGALFVASLSLFTVDQRQYALVFQFGEVVKVISEPGIQFKIPLLQNVRYFDRRVQTIDAEAPELFNTR
EKKNVLVDSFVKWRVVDVSQFYKSVGSEAAAVARLKQTINDGLRAEFGQKTVADVISGQRDQVMETVRKRADADARKIGV
EILDVRLKRVDFPDKISSSVYDRMQSERRTVASQLRSEGAADAERVRAEADKQRDVILAEAYRKAQALKGAGDAKAAAIY
AEAYGKNPEFYAFWRSMEAYKESFKNKSDVMVLDPSSDFFKYLKNPQAGQGKSK
>Mature_293_residues
TERLIPTLAAVVGALFVASLSLFTVDQRQYALVFQFGEVVKVISEPGIQFKIPLLQNVRYFDRRVQTIDAEAPELFNTRE
KKNVLVDSFVKWRVVDVSQFYKSVGSEAAAVARLKQTINDGLRAEFGQKTVADVISGQRDQVMETVRKRADADARKIGVE
ILDVRLKRVDFPDKISSSVYDRMQSERRTVASQLRSEGAADAERVRAEADKQRDVILAEAYRKAQALKGAGDAKAAAIYA
EAYGKNPEFYAFWRSMEAYKESFKNKSDVMVLDPSSDFFKYLKNPQAGQGKSK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=315, Percent_Identity=35.2380952380952, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1786697, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 33072; Mature: 32941

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERLIPTLAAVVGALFVASLSLFTVDQRQYALVFQFGEVVKVISEPGIQFKIPLLQNVR
CCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHH
YFDRRVQTIDAEAPELFNTREKKNVLVDSFVKWRVVDVSQFYKSVGSEAAAVARLKQTIN
HHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DGLRAEFGQKTVADVISGQRDQVMETVRKRADADARKIGVEILDVRLKRVDFPDKISSSV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
YDRMQSERRTVASQLRSEGAADAERVRAEADKQRDVILAEAYRKAQALKGAGDAKAAAIY
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AEAYGKNPEFYAFWRSMEAYKESFKNKSDVMVLDPSSDFFKYLKNPQAGQGKSK
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TERLIPTLAAVVGALFVASLSLFTVDQRQYALVFQFGEVVKVISEPGIQFKIPLLQNVR
CCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHH
YFDRRVQTIDAEAPELFNTREKKNVLVDSFVKWRVVDVSQFYKSVGSEAAAVARLKQTIN
HHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DGLRAEFGQKTVADVISGQRDQVMETVRKRADADARKIGVEILDVRLKRVDFPDKISSSV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
YDRMQSERRTVASQLRSEGAADAERVRAEADKQRDVILAEAYRKAQALKGAGDAKAAAIY
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AEAYGKNPEFYAFWRSMEAYKESFKNKSDVMVLDPSSDFFKYLKNPQAGQGKSK
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]