Click here to switch to the map view.

The map label for this gene is hflK [H]

Identifier: 34498986

GI number: 34498986

Start: 3839146

End: 3840372

Strand: Reverse

Name: hflK [H]

Synonym: CV_3531

Alternate gene names: 34498986

Gene position: 3840372-3839146 (Counterclockwise)

Preceding gene: 34498987

Following gene: 34498985

Centisome position: 80.83

GC content: 65.85

Gene sequence:

>1227_bases
ATGTCGCAGAATGACCCGAACCGTGGCCGCAACGGCCAGAATGGGCCACCGGACCTCGATGAAGTGTTCCGTGATCTGAA
CCGAAAACTTTCCCGCCTGCTGGGCGGCAAGCCCAACAACGGCGGCCAGGGCGGCAATCAGGGCAACCGTCCCGGCGCGT
CGTTCACCCCGCCGTCGTACAAGGGCGGCGCCGCCGTCGTGGTCGGCGTGCTGGCCGCGCTGTGGCTGGCCAGCGGCTTT
TACATCGTCGATGCCCGCGAAGAGGGCGTGGTGCTGCGCCTGGGCAGCTACAACCGGCTGACTGAGCCCGGTTTGCAGTG
GCATGCGCCGTATCCGTTCGAGAAGGCGGAGATCGTCAACCTGACCGAACTGCGCAGCGTCGAGGTCGGCTACCGTGGCA
GCGCGCAGAACCGCGTGCCGGAAGAGTCGCTGATGCTGACCTCGGATCAGAACATCATCGACGTGCAGCTGTCGGTGCAG
TACGACATCAAGGATGCGCGCGCCTTCCTGTTCAACAACGCCGCGCGCGAGCGCGACGGCAAGGACTTGGTCAAGCAGGC
CGCCGAAACCGCGATCCGCGAGGTGGTGGGCCGCAACAAGGTGGACTTCGTGCTGAACGAGGGCCGCGCCCAGATCGCCG
CCGACGCGCGCAAACTGATCCAGGACGTGCTGGACCGCTACCACGCCGGCATCCGCATCGCCAAGGTCAACATCAACGAC
GTGCAGCCGCCGCAGGCGGTGCTGGCCGCCTTCGATGACGCGGTGAAGGCCGGACAGGACAAGGACAAGCTGCGCAATGA
AGGCATGGCCTACGCCAACGAGGTGGTGCCCAAGGCCAAGGGCATGGCCTCGCGCCTGGTGCAGGAGGCCGAAGGCTACC
AGCAGCAGGTGGTCGAGCGCGCCCAGGGCGATGCCGAGCGTTTCAAACAAGTGTTGCCTGAATACAACAAGGCACCCAAG
GTCATGCGCGACCGGCTGTACCTGGACATGATGCAGCAGATCATGAACAACAGCAGCAAGGTGCTGGTGGATCAGAAGGG
CGGCAACAGCCTGCTGTACCTGCCGTTGGACAAGCTCGCTCAGATGGCGTCTGCCAACGCGCCGGCTCCGGCGCAACCCT
CCGCAACCCCGGCTCCGGAGGCTGCGGCCCAGCCGGCTTCGCCGCCGGCGGCGAAGAACGGGCGCGACGCGTCGCGCGGT
CGTGATTTCTTTGGAGCGGAGCGATGA

Upstream 100 bases:

>100_bases
CGCGTGTCGGCGCTGAAAGGCGAGGGCCTGGAACTCTTGCGCGAGGCGATTGCCGAACGGGTGCAACCTTTCGCAAACAA
CCATAAAGAACCATACGAGC

Downstream 100 bases:

>100_bases
CTGAAAGACTGATTCCCACCCTGGCGGCGGTGGTCGGCGCGCTGTTCGTCGCCAGCCTGTCGCTGTTTACCGTCGATCAG
CGCCAGTACGCGCTGGTTTT

Product: transmembrane protein HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSQNDPNRGRNGQNGPPDLDEVFRDLNRKLSRLLGGKPNNGGQGGNQGNRPGASFTPPSYKGGAAVVVGVLAALWLASGF
YIVDAREEGVVLRLGSYNRLTEPGLQWHAPYPFEKAEIVNLTELRSVEVGYRGSAQNRVPEESLMLTSDQNIIDVQLSVQ
YDIKDARAFLFNNAARERDGKDLVKQAAETAIREVVGRNKVDFVLNEGRAQIAADARKLIQDVLDRYHAGIRIAKVNIND
VQPPQAVLAAFDDAVKAGQDKDKLRNEGMAYANEVVPKAKGMASRLVQEAEGYQQQVVERAQGDAERFKQVLPEYNKAPK
VMRDRLYLDMMQQIMNNSSKVLVDQKGGNSLLYLPLDKLAQMASANAPAPAQPSATPAPEAAAQPASPPAAKNGRDASRG
RDFFGAER

Sequences:

>Translated_408_residues
MSQNDPNRGRNGQNGPPDLDEVFRDLNRKLSRLLGGKPNNGGQGGNQGNRPGASFTPPSYKGGAAVVVGVLAALWLASGF
YIVDAREEGVVLRLGSYNRLTEPGLQWHAPYPFEKAEIVNLTELRSVEVGYRGSAQNRVPEESLMLTSDQNIIDVQLSVQ
YDIKDARAFLFNNAARERDGKDLVKQAAETAIREVVGRNKVDFVLNEGRAQIAADARKLIQDVLDRYHAGIRIAKVNIND
VQPPQAVLAAFDDAVKAGQDKDKLRNEGMAYANEVVPKAKGMASRLVQEAEGYQQQVVERAQGDAERFKQVLPEYNKAPK
VMRDRLYLDMMQQIMNNSSKVLVDQKGGNSLLYLPLDKLAQMASANAPAPAQPSATPAPEAAAQPASPPAAKNGRDASRG
RDFFGAER
>Mature_407_residues
SQNDPNRGRNGQNGPPDLDEVFRDLNRKLSRLLGGKPNNGGQGGNQGNRPGASFTPPSYKGGAAVVVGVLAALWLASGFY
IVDAREEGVVLRLGSYNRLTEPGLQWHAPYPFEKAEIVNLTELRSVEVGYRGSAQNRVPEESLMLTSDQNIIDVQLSVQY
DIKDARAFLFNNAARERDGKDLVKQAAETAIREVVGRNKVDFVLNEGRAQIAADARKLIQDVLDRYHAGIRIAKVNINDV
QPPQAVLAAFDDAVKAGQDKDKLRNEGMAYANEVVPKAKGMASRLVQEAEGYQQQVVERAQGDAERFKQVLPEYNKAPKV
MRDRLYLDMMQQIMNNSSKVLVDQKGGNSLLYLPLDKLAQMASANAPAPAQPSATPAPEAAAQPASPPAAKNGRDASRGR
DFFGAER

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=292, Percent_Identity=37.3287671232877, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 44504; Mature: 44372

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNDPNRGRNGQNGPPDLDEVFRDLNRKLSRLLGGKPNNGGQGGNQGNRPGASFTPPSY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
KGGAAVVVGVLAALWLASGFYIVDAREEGVVLRLGSYNRLTEPGLQWHAPYPFEKAEIVN
CCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCEECCCCCCCCHHCCC
LTELRSVEVGYRGSAQNRVPEESLMLTSDQNIIDVQLSVQYDIKDARAFLFNNAARERDG
HHHHHHCCCCCCCCCCCCCCHHHEEEECCCCEEEEEEEEEECHHHHHHHHHHHHHHCCCH
KDLVKQAAETAIREVVGRNKVDFVLNEGRAQIAADARKLIQDVLDRYHAGIRIAKVNIND
HHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
VQPPQAVLAAFDDAVKAGQDKDKLRNEGMAYANEVVPKAKGMASRLVQEAEGYQQQVVER
CCCHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGDAERFKQVLPEYNKAPKVMRDRLYLDMMQQIMNNSSKVLVDQKGGNSLLYLPLDKLA
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHH
QMASANAPAPAQPSATPAPEAAAQPASPPAAKNGRDASRGRDFFGAER
HHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
SQNDPNRGRNGQNGPPDLDEVFRDLNRKLSRLLGGKPNNGGQGGNQGNRPGASFTPPSY
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
KGGAAVVVGVLAALWLASGFYIVDAREEGVVLRLGSYNRLTEPGLQWHAPYPFEKAEIVN
CCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCEECCCCCCCCHHCCC
LTELRSVEVGYRGSAQNRVPEESLMLTSDQNIIDVQLSVQYDIKDARAFLFNNAARERDG
HHHHHHCCCCCCCCCCCCCCHHHEEEECCCCEEEEEEEEEECHHHHHHHHHHHHHHCCCH
KDLVKQAAETAIREVVGRNKVDFVLNEGRAQIAADARKLIQDVLDRYHAGIRIAKVNIND
HHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCC
VQPPQAVLAAFDDAVKAGQDKDKLRNEGMAYANEVVPKAKGMASRLVQEAEGYQQQVVER
CCCHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGDAERFKQVLPEYNKAPKVMRDRLYLDMMQQIMNNSSKVLVDQKGGNSLLYLPLDKLA
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHH
QMASANAPAPAQPSATPAPEAAAQPASPPAAKNGRDASRGRDFFGAER
HHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]