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The map label for this gene is hisZ

Identifier: 34498984

GI number: 34498984

Start: 3837015

End: 3838166

Strand: Reverse

Name: hisZ

Synonym: CV_3529

Alternate gene names: 34498984

Gene position: 3838166-3837015 (Counterclockwise)

Preceding gene: 34498985

Following gene: 34498983

Centisome position: 80.79

GC content: 69.88

Gene sequence:

>1152_bases
ATGCGTAATTGGCTGTTACCCGAATACATCGCTGACATCCTGCCGGCCACCGCGCGCCAGGTGGAGTCGGCCAAGGCCGC
GATGCTGGAAGGCTTTCGCGTGGCCGGCTACGAACTGGTGCTGCCGCCGCTGATCGAATACATCGACTCGCTGGTGAGCG
AAGGCGACGACACGCTGGACCTGAAAACCTTCAAGCTGGACGACCAGCTGTCCGGCCGCCAGCTGGGCCTGCGCGCCGAC
ATCACGCCGCAGGTGGCGCGCATCGACGCCCACCTGCTGGGCGAGCGCACCGGCGTCACCCGCCTGTGTTACGCCGGCAG
CGTGGTGCACAGCCGCCCGTCCGGCCTGACCAGCTCGCGCGAGCCGCTGCAGGTGGGCGCCGAGCTGTACGGCTACGCCG
GCATCGAGGCCGACCAGGAGATCATCGAGCTGATGCTGGCCACGCTGGAAAAGGCCGGCGTGAAGAAGCTGCGGCTGGAT
GTCGGCCATATCGCCATTTACCGCGGCCTGGCCGCGGCGGCCGGGCTGTCGCCCGAGGTCAGTCGCGAGCTGTTCGGCCT
GCTGCAGAACAAGGACGCCGCCGGCATCGCCGCGCGGGTGGCCGGCGTGGCCGAGCCTTACAAGAGCGCTTTCCTGGCGC
TGCCGGAACTGTACGGCCCGGCCGCGGTGCTGGAGAAGGCGCGCACCCGGCTGCCCTCGCTGCCTGAAGTGGAGCTGGGC
TTGATGCAGCTGTCCGCCATCGCCCGCGCGATGGAGGGCAGGGTGGAGCTGAGCTTCGACCTGGCCGAGCTGCGCGGCGA
CTTCTACCACACCGGCCTGATGTTCGCGGCCTACGCGCCCGGCTGGTCCGACGCGATCGCCCGCGGCGGCCGCTACGACA
ATGTCGGCCGCCGCTTCGGCCGCGCCCGTCCCGCCACCGGCTTCAGCCTGGACCTGCGCGACCTGTTGCGCATCCTGCCG
GAGCGAGACCCCAGCCGTGGCATCCGCGTCTCCGCGCGGCATCTGCCGGCGGCCGCCGCGGAAGTGTCGAGGCTGCGCGC
CGAAGGCGAGATGGTGGTGGTGGATTATCTGGGCGAATCCGCGGCCGCGCTCAATTGCGACCGAGAGTTGGTTCCCGCTG
CCGATGGTTGGCAGCTGGCGCCGTTTCATTGA

Upstream 100 bases:

>100_bases
AGGCGACAATTGATTTTTTGAGAAGACTGGCCGGGGCGACCTGGCCAGTTTGCTGATGACAAGGCGGGTCCTTCCCCGCC
TTTTATTCTGTTGAAACGAA

Downstream 100 bases:

>100_bases
ATTTTTGTTTGAATCTGACTGACGAAGAGGTTTTTTCCAATGTCCAAGAACGTTGTCGTGATTGGCACCCAGTGGGGTGA
CGAAGGCAAAGGCAAAATCG

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRNWLLPEYIADILPATARQVESAKAAMLEGFRVAGYELVLPPLIEYIDSLVSEGDDTLDLKTFKLDDQLSGRQLGLRAD
ITPQVARIDAHLLGERTGVTRLCYAGSVVHSRPSGLTSSREPLQVGAELYGYAGIEADQEIIELMLATLEKAGVKKLRLD
VGHIAIYRGLAAAAGLSPEVSRELFGLLQNKDAAGIAARVAGVAEPYKSAFLALPELYGPAAVLEKARTRLPSLPEVELG
LMQLSAIARAMEGRVELSFDLAELRGDFYHTGLMFAAYAPGWSDAIARGGRYDNVGRRFGRARPATGFSLDLRDLLRILP
ERDPSRGIRVSARHLPAAAAEVSRLRAEGEMVVVDYLGESAAALNCDRELVPAADGWQLAPFH

Sequences:

>Translated_383_residues
MRNWLLPEYIADILPATARQVESAKAAMLEGFRVAGYELVLPPLIEYIDSLVSEGDDTLDLKTFKLDDQLSGRQLGLRAD
ITPQVARIDAHLLGERTGVTRLCYAGSVVHSRPSGLTSSREPLQVGAELYGYAGIEADQEIIELMLATLEKAGVKKLRLD
VGHIAIYRGLAAAAGLSPEVSRELFGLLQNKDAAGIAARVAGVAEPYKSAFLALPELYGPAAVLEKARTRLPSLPEVELG
LMQLSAIARAMEGRVELSFDLAELRGDFYHTGLMFAAYAPGWSDAIARGGRYDNVGRRFGRARPATGFSLDLRDLLRILP
ERDPSRGIRVSARHLPAAAAEVSRLRAEGEMVVVDYLGESAAALNCDRELVPAADGWQLAPFH
>Mature_383_residues
MRNWLLPEYIADILPATARQVESAKAAMLEGFRVAGYELVLPPLIEYIDSLVSEGDDTLDLKTFKLDDQLSGRQLGLRAD
ITPQVARIDAHLLGERTGVTRLCYAGSVVHSRPSGLTSSREPLQVGAELYGYAGIEADQEIIELMLATLEKAGVKKLRLD
VGHIAIYRGLAAAAGLSPEVSRELFGLLQNKDAAGIAARVAGVAEPYKSAFLALPELYGPAAVLEKARTRLPSLPEVELG
LMQLSAIARAMEGRVELSFDLAELRGDFYHTGLMFAAYAPGWSDAIARGGRYDNVGRRFGRARPATGFSLDLRDLLRILP
ERDPSRGIRVSARHLPAAAAEVSRLRAEGEMVVVDYLGESAAALNCDRELVPAADGWQLAPFH

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HISZ_CHRVO (Q7NS97)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903199.1
- ProteinModelPortal:   Q7NS97
- SMR:   Q7NS97
- GeneID:   2547623
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3529
- NMPDR:   fig|243365.1.peg.3529
- HOGENOM:   HBG616575
- OMA:   DLRGYHY
- ProtClustDB:   PRK12292
- BioCyc:   CVIO243365:CV_3529-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00125
- InterPro:   IPR004517
- InterPro:   IPR004516
- PANTHER:   PTHR11476
- PIRSF:   PIRSF001549
- TIGRFAMs:   TIGR00443

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41500; Mature: 41500

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNWLLPEYIADILPATARQVESAKAAMLEGFRVAGYELVLPPLIEYIDSLVSEGDDTLD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEHHHHHHHHHHHHHHCCCCCEE
LKTFKLDDQLSGRQLGLRADITPQVARIDAHLLGERTGVTRLCYAGSVVHSRPSGLTSSR
EEEEEECCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHCCCCCCCCCC
EPLQVGAELYGYAGIEADQEIIELMLATLEKAGVKKLRLDVGHIAIYRGLAAAAGLSPEV
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHH
SRELFGLLQNKDAAGIAARVAGVAEPYKSAFLALPELYGPAAVLEKARTRLPSLPEVELG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHH
LMQLSAIARAMEGRVELSFDLAELRGDFYHTGLMFAAYAPGWSDAIARGGRYDNVGRRFG
HHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHEECCCCHHHHHHCCCCCCHHHHHHC
RARPATGFSLDLRDLLRILPERDPSRGIRVSARHLPAAAAEVSRLRAEGEMVVVDYLGES
CCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEHHHCCHHHHHHHHHHCCCCEEEEEECCCC
AAALNCDRELVPAADGWQLAPFH
HHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRNWLLPEYIADILPATARQVESAKAAMLEGFRVAGYELVLPPLIEYIDSLVSEGDDTLD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEHHHHHHHHHHHHHHCCCCCEE
LKTFKLDDQLSGRQLGLRADITPQVARIDAHLLGERTGVTRLCYAGSVVHSRPSGLTSSR
EEEEEECCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHCCCCCCCCCC
EPLQVGAELYGYAGIEADQEIIELMLATLEKAGVKKLRLDVGHIAIYRGLAAAAGLSPEV
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHH
SRELFGLLQNKDAAGIAARVAGVAEPYKSAFLALPELYGPAAVLEKARTRLPSLPEVELG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHH
LMQLSAIARAMEGRVELSFDLAELRGDFYHTGLMFAAYAPGWSDAIARGGRYDNVGRRFG
HHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHEECCCCHHHHHHCCCCCCHHHHHHC
RARPATGFSLDLRDLLRILPERDPSRGIRVSARHLPAAAAEVSRLRAEGEMVVVDYLGES
CCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEHHHCCHHHHHHHHHHCCCCEEEEEECCCC
AAALNCDRELVPAADGWQLAPFH
HHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782