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The map label for this gene is queC

Identifier: 34498962

GI number: 34498962

Start: 3807118

End: 3807822

Strand: Direct

Name: queC

Synonym: CV_3507

Alternate gene names: 34498962

Gene position: 3807118-3807822 (Clockwise)

Preceding gene: 34498959

Following gene: 34498963

Centisome position: 80.13

GC content: 67.8

Gene sequence:

>705_bases
ATGAACCAAGCATCTGATGAAAAAGCCCTGGTGGTGCTCTCGGGCGGCCAGGACTCGACCACCTGCCTCTACTGGGCGCT
GCGCCGTTTCGGCGCCGGCAAGGTTGAAGCCGTCACCTTCGATTACGGCCAACGCCACCGCGTGGAGCTGGACTGCGCGC
GCAAGATCGCCGCACTCGCCGGCGTGCGCCAGACCGTGCTGCCGATCGACACCTTCGCCGCCATCGGCGGCAACGCGCTG
ACCGATGCCAGCATCGCCCCGGAAGAAGGCGTCCGCGACGACGACGCCCTGCCTAACACCTTCGTCCCCGGGCGCAATCT
GGTCTTCCTCACCTTCGCCGCCGCCTTCGCCTATACCCGCGGCGCGCGCCACCTGGTGACCGGCGTCGCCCAGACCGACT
ACTCCGGCTATCCCGATTGCCGCGAGAACACGCTGAAGGCGCTGGAAGTGGCGCTGCGGCTGGGCATGGATAGCCGGGTA
GAGCTGCACACGCCGCTGATGTACCTGTCCAAGGCCGAAACTGTGACCCTGGCGCAACAGGTTGGCGCGCTGGAGGCCCT
GGCCTGGAGTCACACCTGTTACAACGGCGAGGTGCCGCCCTGCGGCCATTGCGCGTCGTGCGAGCTGCGCGCCAAGGGTT
TCGCCGAGGCAGGCGTGCCGGACCCGCTGGTGGAACGCTGCCAGGCCGAAGCGCAAGGACTCTGA

Upstream 100 bases:

>100_bases
CCCGCCAGGTCTATAGTGGGTTAAAATCATCGGTTTGCGCGGCGGGTGAGACCGATCCCGGCGCGCCGTCACAAACCCCT
CGACTGTTTTTCGACGGAAC

Downstream 100 bases:

>100_bases
GATGCACGCCTGTTACCTGATAGCCGGCGCCGGCTTCGAAGCGGCGCGGCGGTTGCCGGCCGACCACGGCAAGGCCGCGC
GCCCTCATGGCCACAGTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNQASDEKALVVLSGGQDSTTCLYWALRRFGAGKVEAVTFDYGQRHRVELDCARKIAALAGVRQTVLPIDTFAAIGGNAL
TDASIAPEEGVRDDDALPNTFVPGRNLVFLTFAAAFAYTRGARHLVTGVAQTDYSGYPDCRENTLKALEVALRLGMDSRV
ELHTPLMYLSKAETVTLAQQVGALEALAWSHTCYNGEVPPCGHCASCELRAKGFAEAGVPDPLVERCQAEAQGL

Sequences:

>Translated_234_residues
MNQASDEKALVVLSGGQDSTTCLYWALRRFGAGKVEAVTFDYGQRHRVELDCARKIAALAGVRQTVLPIDTFAAIGGNAL
TDASIAPEEGVRDDDALPNTFVPGRNLVFLTFAAAFAYTRGARHLVTGVAQTDYSGYPDCRENTLKALEVALRLGMDSRV
ELHTPLMYLSKAETVTLAQQVGALEALAWSHTCYNGEVPPCGHCASCELRAKGFAEAGVPDPLVERCQAEAQGL
>Mature_234_residues
MNQASDEKALVVLSGGQDSTTCLYWALRRFGAGKVEAVTFDYGQRHRVELDCARKIAALAGVRQTVLPIDTFAAIGGNAL
TDASIAPEEGVRDDDALPNTFVPGRNLVFLTFAAAFAYTRGARHLVTGVAQTDYSGYPDCRENTLKALEVALRLGMDSRV
ELHTPLMYLSKAETVTLAQQVGALEALAWSHTCYNGEVPPCGHCASCELRAKGFAEAGVPDPLVERCQAEAQGL

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=231, Percent_Identity=46.3203463203463, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_CHRVO (Q7NSB9)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903177.1
- ProteinModelPortal:   Q7NSB9
- SMR:   Q7NSB9
- GeneID:   2548657
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3507
- NMPDR:   fig|243365.1.peg.3507
- HOGENOM:   HBG553284
- OMA:   CASCELR
- PhylomeDB:   Q7NSB9
- ProtClustDB:   CLSK2485620
- BioCyc:   CVIO243365:CV_3507-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25093; Mature: 25093

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQASDEKALVVLSGGQDSTTCLYWALRRFGAGKVEAVTFDYGQRHRVELDCARKIAALA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHH
GVRQTVLPIDTFAAIGGNALTDASIAPEEGVRDDDALPNTFVPGRNLVFLTFAAAFAYTR
HHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHC
GARHLVTGVAQTDYSGYPDCRENTLKALEVALRLGMDSRVELHTPLMYLSKAETVTLAQQ
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHCCHHHHHCCHHHHHHHH
VGALEALAWSHTCYNGEVPPCGHCASCELRAKGFAEAGVPDPLVERCQAEAQGL
HHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNQASDEKALVVLSGGQDSTTCLYWALRRFGAGKVEAVTFDYGQRHRVELDCARKIAALA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHH
GVRQTVLPIDTFAAIGGNALTDASIAPEEGVRDDDALPNTFVPGRNLVFLTFAAAFAYTR
HHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHC
GARHLVTGVAQTDYSGYPDCRENTLKALEVALRLGMDSRVELHTPLMYLSKAETVTLAQQ
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHCCHHHHHCCHHHHHHHH
VGALEALAWSHTCYNGEVPPCGHCASCELRAKGFAEAGVPDPLVERCQAEAQGL
HHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782