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The map label for this gene is treR [H]

Identifier: 34498757

GI number: 34498757

Start: 3596211

End: 3596915

Strand: Reverse

Name: treR [H]

Synonym: CV_3302

Alternate gene names: 34498757

Gene position: 3596915-3596211 (Counterclockwise)

Preceding gene: 34498758

Following gene: 34498755

Centisome position: 75.71

GC content: 62.41

Gene sequence:

>705_bases
GTGAACAAATACCATCAAATCTATTCCGACATCGTCGCCGACATCGACAACCGGCGCTACGCCCAGGGCGAGCGCATCCC
GTCAGAATCCGAGCTGATGCACCACTACGACGCCAGCCGCGGCACCGTGCGCAAGGCGGTGGACATGCTGCAGGAACGGG
GCTACGTGCAGAAAATCCACGGCAAGGGCATGTTCGTGCTCAAGCCGGGCAATATCGAATTCCAGCTCAGCGGCATCGTC
AGCTTCCAGGAAATGAACGAGCGCATGGGGCGCAAGGTGGTGTCGCGGGTGGCGGAGCTGGCGCAGCTGCCGGCCGACAC
GGCGCTGGCCCAGGCCACCGGCCTGGCCGAGGGCACCGCCATGGTCAAGATCAAGCGGGTGCGCAATATCGACGGCGAGA
ACGTGATCCTGGACATCAACCACTTCGTCGCCGGCCTGGTGCCGGGCCTGAACGCGGACATCGCCGCCGGCTCCATCTAC
CGCTACATCGAGCAGGATCTGGGGCTGACCATCAGCTACGCCCAGCGCATCATCGAAGCCCAGCCCTGCAACGACGACGA
CCGCCGCTACCTGGACCTGAACGGCATGGACCACGTGATCGTGGTCAAGAACCTGACCCACCTCTACGACGGCAGGCTGT
TCGAATACACCGAGTCGCGGCATCGATTGGACAAGTTCTATTTTACGGATATTGCGAGGCGGTAG

Upstream 100 bases:

>100_bases
CTATTGGGATTGAGCGCGGCGCCGGTTTGCCGCGCCGGCCCCGGCTTGCTAAGGTAGGGCCTCGCCGCGCAGGGGCCGCG
AGCACAAGAAGACAAACAAC

Downstream 100 bases:

>100_bases
CGTTTTTCATCAGGGTGTGGGTGTGCGGAGACAGGCCACACTTCATTCCACCTGGTTGATACGATGGAAATCGTGGTCTG
TCCCCCTTTTTTCCGGTCCC

Product: transcriptional repressor of the trehalose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNKYHQIYSDIVADIDNRRYAQGERIPSESELMHHYDASRGTVRKAVDMLQERGYVQKIHGKGMFVLKPGNIEFQLSGIV
SFQEMNERMGRKVVSRVAELAQLPADTALAQATGLAEGTAMVKIKRVRNIDGENVILDINHFVAGLVPGLNADIAAGSIY
RYIEQDLGLTISYAQRIIEAQPCNDDDRRYLDLNGMDHVIVVKNLTHLYDGRLFEYTESRHRLDKFYFTDIARR

Sequences:

>Translated_234_residues
MNKYHQIYSDIVADIDNRRYAQGERIPSESELMHHYDASRGTVRKAVDMLQERGYVQKIHGKGMFVLKPGNIEFQLSGIV
SFQEMNERMGRKVVSRVAELAQLPADTALAQATGLAEGTAMVKIKRVRNIDGENVILDINHFVAGLVPGLNADIAAGSIY
RYIEQDLGLTISYAQRIIEAQPCNDDDRRYLDLNGMDHVIVVKNLTHLYDGRLFEYTESRHRLDKFYFTDIARR
>Mature_234_residues
MNKYHQIYSDIVADIDNRRYAQGERIPSESELMHHYDASRGTVRKAVDMLQERGYVQKIHGKGMFVLKPGNIEFQLSGIV
SFQEMNERMGRKVVSRVAELAQLPADTALAQATGLAEGTAMVKIKRVRNIDGENVILDINHFVAGLVPGLNADIAAGSIY
RYIEQDLGLTISYAQRIIEAQPCNDDDRRYLDLNGMDHVIVVKNLTHLYDGRLFEYTESRHRLDKFYFTDIARR

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790540, Length=236, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=28.0172413793103, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790118, Length=168, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26677; Mature: 26677

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYHQIYSDIVADIDNRRYAQGERIPSESELMHHYDASRGTVRKAVDMLQERGYVQKIH
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEC
GKGMFVLKPGNIEFQLSGIVSFQEMNERMGRKVVSRVAELAQLPADTALAQATGLAEGTA
CCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHH
MVKIKRVRNIDGENVILDINHFVAGLVPGLNADIAAGSIYRYIEQDLGLTISYAQRIIEA
HEEEHHHHCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEHHHHHHHHHC
QPCNDDDRRYLDLNGMDHVIVVKNLTHLYDGRLFEYTESRHRLDKFYFTDIARR
CCCCCCCCEEEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKYHQIYSDIVADIDNRRYAQGERIPSESELMHHYDASRGTVRKAVDMLQERGYVQKIH
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEC
GKGMFVLKPGNIEFQLSGIVSFQEMNERMGRKVVSRVAELAQLPADTALAQATGLAEGTA
CCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHH
MVKIKRVRNIDGENVILDINHFVAGLVPGLNADIAAGSIYRYIEQDLGLTISYAQRIIEA
HEEEHHHHCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEHHHHHHHHHC
QPCNDDDRRYLDLNGMDHVIVVKNLTHLYDGRLFEYTESRHRLDKFYFTDIARR
CCCCCCCCEEEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]