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The map label for this gene is treB [H]

Identifier: 34498755

GI number: 34498755

Start: 3592153

End: 3593607

Strand: Reverse

Name: treB [H]

Synonym: CV_3300

Alternate gene names: 34498755

Gene position: 3593607-3592153 (Counterclockwise)

Preceding gene: 34498757

Following gene: 34498754

Centisome position: 75.64

GC content: 65.5

Gene sequence:

>1455_bases
ATGAGTCACGACTATCAGGCGATCGCCGCGCGGATACTGGAAAATATCGGCGGCGCTGGCAATATCCGCCAAGCTGCGCA
CTGCCTCACCCGGCTGCGCATCTCTTTGAACGACGAATCCAAGGTGAATGGGGACGCGCTGCGCCAGGTGGCGCTGGTGA
AGGGCCACTTCATCAATGCCGGGGTATTTCAGATCGTCATCGGCTCCGGCGATGTGGACCGCGTCTACGCCGAGATGGTG
AAGCAGGGCGGCGTGGCGCGCGCCACCATCGCCGACGTCAAGGCCAGCGGCGACGCCAAGCAGAACCGCTTGCAGCAGCT
GGTCAAGGTGTTCTCCGACGTGTTCATGCCGATATTGCCGGCCATCGTCATCGCCGGCCTGCTGATGGGCGCCAACAATC
TCTTGGGCGCCAAGGGCATGTTCATCGCGGACAAGAGCCTGCTGGACGCCTATCCGGGCCTGTCGGGCTTGTGGGGCCTG
ATCAATATGATGGCCAACACCTCCTTCGTGTTCCTGCCGGCGCTGGTGGGCTGGTCGGCGGCCAAACGCTTCGGCGGCAG
CGAGATTCTCGGCATCGTGCTGGGCCTGCTGCTGGTGCATCCGGACTTGCTCAACGCCTGGAACTACGGCAAGGCGGCGG
CCGGGCTGGACGGCGCCTCGGTGCCTTACTTTGATCTCTTTGGCCTGCATATCGAGAAGGTGGGCTATCAGGGCCAGATC
CTGCCCATCCTGGCCGCGGCCTGGGTGATGTGCCGCGTTGAGCTGTGGCTGAAGCCCAGGGTGCCCAACGCGGTGCAGCT
CTTGGTGGTGCCCATCGTCACCATCGCGGTCAGCGGCTTCCTGGCGCTGGCGGTGATCGGTCCGCTGGCCCGCCACCTGG
GCATTGCTGTCACCGACGCGCTGGTTTACGTGTTCAACCTGGCGCCGTGGCTGGGCGCGGCCTTGTTCGGCGCGCTGTAC
GCGCCGCTGGTGCTGACCGGCATGCACCATATGTTCATCGCGGTGGACTTGCAGCTGATCTCCAGCCAGGGCGGCACCTT
CATCTGGCCGATGATCGCGCTGTCCAATATCGCCCAGGGCAGCGCCGCGCTGGCGATGTTCTGGCTGGCCAGGAACGCCA
ACGACAAGAACATGGCGTCCACCTCGGCGGTGTCGGCCTTCTTCGGCATCACCGAGCCGGCGATGTTCGGCGTCAATCTG
CGCTACAAGCTGCCGTTCTACGCGGCGCTGGCCGGCTCCGCCTGCGCGGCGGTGTTGATCAGCCTGGGCCACGTCAAGGC
GTCGGCGATCGGCGTCGGCGGCCTGCCGGCCTTTATCTCCATCATTCCGCAGCACATCCCGCTGTTCCTGGCGGGCACCC
TGGTGGCCTTGGCCCTGCCCTTCGGCCTGACCTGGCTGCTGGCGCGCCGCCAGCTGGCCGCTGCCGCTCAAGAGGAGGCC
GCGCAAAATGTCTAA

Upstream 100 bases:

>100_bases
TGCCCTCGGTTGCCATGCAGACAATCACCACAAACAGGCGGATTTCGGGCATCGTGAATAGACGCTGACCCGCCGCCGCA
ACAAGGGACAGGGAGGGATG

Downstream 100 bases:

>100_bases
GGACATGAAACGGGCGGTGGTGTACCAGATCTACCCCAAGAGCTTCAGCAGCCATCGCAATCAGGCGACGGGGGATCTCC
TGGGCGTGGTGGACCGGCTG

Product: protein-N p-phosphohistidine-sugar phosphotransferase

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSHDYQAIAARILENIGGAGNIRQAAHCLTRLRISLNDESKVNGDALRQVALVKGHFINAGVFQIVIGSGDVDRVYAEMV
KQGGVARATIADVKASGDAKQNRLQQLVKVFSDVFMPILPAIVIAGLLMGANNLLGAKGMFIADKSLLDAYPGLSGLWGL
INMMANTSFVFLPALVGWSAAKRFGGSEILGIVLGLLLVHPDLLNAWNYGKAAAGLDGASVPYFDLFGLHIEKVGYQGQI
LPILAAAWVMCRVELWLKPRVPNAVQLLVVPIVTIAVSGFLALAVIGPLARHLGIAVTDALVYVFNLAPWLGAALFGALY
APLVLTGMHHMFIAVDLQLISSQGGTFIWPMIALSNIAQGSAALAMFWLARNANDKNMASTSAVSAFFGITEPAMFGVNL
RYKLPFYAALAGSACAAVLISLGHVKASAIGVGGLPAFISIIPQHIPLFLAGTLVALALPFGLTWLLARRQLAAAAQEEA
AQNV

Sequences:

>Translated_484_residues
MSHDYQAIAARILENIGGAGNIRQAAHCLTRLRISLNDESKVNGDALRQVALVKGHFINAGVFQIVIGSGDVDRVYAEMV
KQGGVARATIADVKASGDAKQNRLQQLVKVFSDVFMPILPAIVIAGLLMGANNLLGAKGMFIADKSLLDAYPGLSGLWGL
INMMANTSFVFLPALVGWSAAKRFGGSEILGIVLGLLLVHPDLLNAWNYGKAAAGLDGASVPYFDLFGLHIEKVGYQGQI
LPILAAAWVMCRVELWLKPRVPNAVQLLVVPIVTIAVSGFLALAVIGPLARHLGIAVTDALVYVFNLAPWLGAALFGALY
APLVLTGMHHMFIAVDLQLISSQGGTFIWPMIALSNIAQGSAALAMFWLARNANDKNMASTSAVSAFFGITEPAMFGVNL
RYKLPFYAALAGSACAAVLISLGHVKASAIGVGGLPAFISIIPQHIPLFLAGTLVALALPFGLTWLLARRQLAAAAQEEA
AQNV
>Mature_483_residues
SHDYQAIAARILENIGGAGNIRQAAHCLTRLRISLNDESKVNGDALRQVALVKGHFINAGVFQIVIGSGDVDRVYAEMVK
QGGVARATIADVKASGDAKQNRLQQLVKVFSDVFMPILPAIVIAGLLMGANNLLGAKGMFIADKSLLDAYPGLSGLWGLI
NMMANTSFVFLPALVGWSAAKRFGGSEILGIVLGLLLVHPDLLNAWNYGKAAAGLDGASVPYFDLFGLHIEKVGYQGQIL
PILAAAWVMCRVELWLKPRVPNAVQLLVVPIVTIAVSGFLALAVIGPLARHLGIAVTDALVYVFNLAPWLGAALFGALYA
PLVLTGMHHMFIAVDLQLISSQGGTFIWPMIALSNIAQGSAALAMFWLARNANDKNMASTSAVSAFFGITEPAMFGVNLR
YKLPFYAALAGSACAAVLISLGHVKASAIGVGGLPAFISIIPQHIPLFLAGTLVALALPFGLTWLLARRQLAAAAQEEAA
QNV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=452, Percent_Identity=41.1504424778761, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1790159, Length=486, Percent_Identity=28.8065843621399, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI48994906, Length=507, Percent_Identity=27.4161735700197, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1788769, Length=423, Percent_Identity=28.8416075650118, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51077; Mature: 50946

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDYQAIAARILENIGGAGNIRQAAHCLTRLRISLNDESKVNGDALRQVALVKGHFINA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCCC
GVFQIVIGSGDVDRVYAEMVKQGGVARATIADVKASGDAKQNRLQQLVKVFSDVFMPILP
CEEEEEECCCCHHHHHHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AIVIAGLLMGANNLLGAKGMFIADKSLLDAYPGLSGLWGLINMMANTSFVFLPALVGWSA
HHHHHHHHHCCCCCCCCCCCEEECHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
AKRFGGSEILGIVLGLLLVHPDLLNAWNYGKAAAGLDGASVPYFDLFGLHIEKVGYQGQI
HHHCCCHHHHHHHHHHHHHCHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCCH
LPILAAAWVMCRVELWLKPRVPNAVQLLVVPIVTIAVSGFLALAVIGPLARHLGIAVTDA
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVYVFNLAPWLGAALFGALYAPLVLTGMHHMFIAVDLQLISSQGGTFIWPMIALSNIAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCC
SAALAMFWLARNANDKNMASTSAVSAFFGITEPAMFGVNLRYKLPFYAALAGSACAAVLI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHCCCEEEEECCHHHHHHHHHHHHHHH
SLGHVKASAIGVGGLPAFISIIPQHIPLFLAGTLVALALPFGLTWLLARRQLAAAAQEEA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQNV
HCCC
>Mature Secondary Structure 
SHDYQAIAARILENIGGAGNIRQAAHCLTRLRISLNDESKVNGDALRQVALVKGHFINA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCCC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HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129 [H]