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The map label for this gene is yhdG [H]

Identifier: 34498751

GI number: 34498751

Start: 3586914

End: 3588311

Strand: Reverse

Name: yhdG [H]

Synonym: CV_3296

Alternate gene names: 34498751

Gene position: 3588311-3586914 (Counterclockwise)

Preceding gene: 34498752

Following gene: 34498745

Centisome position: 75.53

GC content: 65.31

Gene sequence:

>1398_bases
ATGAGTTTGATGCGCAAGAAGAGCGTGCAAGGCATGTTGGCCGCCGCTCAGACTTCGCGCGGGCTGCGAAAAGAGCTCTC
CGCGTTCGACCTTACCATGCTGGGCATCGGCGCCATCATCGGCACCGGCATTTTCGTGCTCACCGGCACCGGCGCCACCA
TCGCCGGCCCCGGCCTGGTGCTTTCCTTCGTCATCAGCGCCTTCGCCTGCGGCTTCGCAGCGATGTGCTATGCCGAATTC
GCTTCCATGCTGCCGATTTCCGGCTCCACTTACACCTACGCCTACGCCACGCTGGGCGAGCTGATCGCCTGGATCATCGG
CTGGGACCTGCTGCTGGAATACCTGCTGGCCTCGTCCGCGGTGTCGGTCGGCTGGTCCGGCTACTTCCAGAGCCTGCTGT
CCGGCTTCGGCGTCACGCTGCCGCAGGCGCTGACCGCCGCCGCCGGCTCGGTGCCGGGCAAGGAAACCTTGTTCAACCTG
CCGGCCTTCTGCATCGCGATGATCATCACCGCGCTGCTGGCCTTCGGCATCAAGGAATCGAAGCGCGTCAACAACATCGT
GGTGCTGATCAAGGTGGCGGTGGTGGTGCTGTTCATCGCCATCGGCGTGTGGCACGTCAAGCCGGCCAACTGGCAGCCGG
CGCTGCCGTTCGGCTTCTCCGGCGTGTTCCACGGCGCCGCCATCGTGTTCTTCAGCTTCATCGGCTTCGACGCCGTCACC
TGCGCGGCGGAAGAGGTGAAGAACCCGGCCAAGGACATCCCGCGCGGCGTGATCTGGTCGCTGGTGGTGTGCTCCATCCT
GTACGTGGTGGTGGCAGCCATCATGACCGGCATCGTGCCCTACATGAACTTCGCCGGCGTCGACCACCCGGTGTCGCTGG
CGCTGCAGGTGGCCAAGCTGGACTGGTTCGCCGGCTTCGTCGACCTGGGCGCCATCCTGGGCATGATGACCGTGATCCTG
GTGATGACCTACGGCCAGACCCGCATCCTGTTCGCGATGAGCCGCGACGGCCTGCTGCCCAAGATCTTTTCCGAGGTGAA
CCCCAAGTACGGCACCCCGTACAAGGCCACCTGGCTGATCGGCACCATCATCGCGCTGCTGGCCGGCTTCGTGCCGCTGC
ACACGCTGGCCGAGCTGGTGAACATCGGCACCCTGGCCGCGTTCACGCTGATCGCGCTGTCGGTGATCGTGCTGCGCAAG
CGCGAGCCGGACCTGCCGCGCAAGTTCGTCTGCCCGGCGGTGCCCACCATTCCGGCGCTGGCCATCCTGTGCTGCGGTTT
CCTGATGACCCAGCTGTCGCTGCTGACCTGGACCTGCTTCGCCGCCTGGCTGTTGATCGGCCTGGTGGTGTACTTCGGCT
ACTCGCGGCGCAATTCGCTGCTGCACAATCCGGCCTGA

Upstream 100 bases:

>100_bases
ATGAGGCGCCCGCCTGGACAGCGGGCGTCTTGTCGTTTCAGCGCCGCCGCGACGTACGGCGGCGCGGGCCGGTTTCGGGG
TAAATACGGGATAGTAGACA

Downstream 100 bases:

>100_bases
TTCAGGCTGTGTTTGAAATGGCGGAGCCCATGGGCTCCGCTTTTTTTGTTTCCGCCTCAGGCCGGCCGGTCGAGCCGGCG
CAGCAGCAGATGGCAGGCTC

Product: amino-acid transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSLMRKKSVQGMLAAAQTSRGLRKELSAFDLTMLGIGAIIGTGIFVLTGTGATIAGPGLVLSFVISAFACGFAAMCYAEF
ASMLPISGSTYTYAYATLGELIAWIIGWDLLLEYLLASSAVSVGWSGYFQSLLSGFGVTLPQALTAAAGSVPGKETLFNL
PAFCIAMIITALLAFGIKESKRVNNIVVLIKVAVVVLFIAIGVWHVKPANWQPALPFGFSGVFHGAAIVFFSFIGFDAVT
CAAEEVKNPAKDIPRGVIWSLVVCSILYVVVAAIMTGIVPYMNFAGVDHPVSLALQVAKLDWFAGFVDLGAILGMMTVIL
VMTYGQTRILFAMSRDGLLPKIFSEVNPKYGTPYKATWLIGTIIALLAGFVPLHTLAELVNIGTLAAFTLIALSVIVLRK
REPDLPRKFVCPAVPTIPALAILCCGFLMTQLSLLTWTCFAAWLLIGLVVYFGYSRRNSLLHNPA

Sequences:

>Translated_465_residues
MSLMRKKSVQGMLAAAQTSRGLRKELSAFDLTMLGIGAIIGTGIFVLTGTGATIAGPGLVLSFVISAFACGFAAMCYAEF
ASMLPISGSTYTYAYATLGELIAWIIGWDLLLEYLLASSAVSVGWSGYFQSLLSGFGVTLPQALTAAAGSVPGKETLFNL
PAFCIAMIITALLAFGIKESKRVNNIVVLIKVAVVVLFIAIGVWHVKPANWQPALPFGFSGVFHGAAIVFFSFIGFDAVT
CAAEEVKNPAKDIPRGVIWSLVVCSILYVVVAAIMTGIVPYMNFAGVDHPVSLALQVAKLDWFAGFVDLGAILGMMTVIL
VMTYGQTRILFAMSRDGLLPKIFSEVNPKYGTPYKATWLIGTIIALLAGFVPLHTLAELVNIGTLAAFTLIALSVIVLRK
REPDLPRKFVCPAVPTIPALAILCCGFLMTQLSLLTWTCFAAWLLIGLVVYFGYSRRNSLLHNPA
>Mature_464_residues
SLMRKKSVQGMLAAAQTSRGLRKELSAFDLTMLGIGAIIGTGIFVLTGTGATIAGPGLVLSFVISAFACGFAAMCYAEFA
SMLPISGSTYTYAYATLGELIAWIIGWDLLLEYLLASSAVSVGWSGYFQSLLSGFGVTLPQALTAAAGSVPGKETLFNLP
AFCIAMIITALLAFGIKESKRVNNIVVLIKVAVVVLFIAIGVWHVKPANWQPALPFGFSGVFHGAAIVFFSFIGFDAVTC
AAEEVKNPAKDIPRGVIWSLVVCSILYVVVAAIMTGIVPYMNFAGVDHPVSLALQVAKLDWFAGFVDLGAILGMMTVILV
MTYGQTRILFAMSRDGLLPKIFSEVNPKYGTPYKATWLIGTIIALLAGFVPLHTLAELVNIGTLAAFTLIALSVIVLRKR
EPDLPRKFVCPAVPTIPALAILCCGFLMTQLSLLTWTCFAAWLLIGLVVYFGYSRRNSLLHNPA

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=417, Percent_Identity=36.4508393285372, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI258614003, Length=429, Percent_Identity=34.2657342657343, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI258614005, Length=429, Percent_Identity=34.2657342657343, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=34.8623853211009, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI258645169, Length=429, Percent_Identity=34.965034965035, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI110347453, Length=400, Percent_Identity=35.5, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI114326544, Length=438, Percent_Identity=31.0502283105023, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI114326550, Length=438, Percent_Identity=31.0502283105023, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI115648063, Length=424, Percent_Identity=23.1132075471698, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI115648022, Length=424, Percent_Identity=23.1132075471698, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910308, Length=408, Percent_Identity=25.7352941176471, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI186910306, Length=408, Percent_Identity=25.7352941176471, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI186910304, Length=408, Percent_Identity=25.7352941176471, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=25.4424778761062, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187423910, Length=486, Percent_Identity=23.4567901234568, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7657591, Length=486, Percent_Identity=23.4567901234568, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7657683, Length=399, Percent_Identity=25.31328320802, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI33286428, Length=401, Percent_Identity=24.4389027431421, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081869, Length=405, Percent_Identity=27.4074074074074, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082023, Length=458, Percent_Identity=27.5109170305677, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788480, Length=375, Percent_Identity=28.8, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786302, Length=354, Percent_Identity=23.728813559322, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082250, Length=467, Percent_Identity=27.6231263383298, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790653, Length=471, Percent_Identity=23.5668789808917, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786789, Length=376, Percent_Identity=21.2765957446809, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786602, Length=416, Percent_Identity=24.2788461538462, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789017, Length=411, Percent_Identity=25.5474452554745, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081708, Length=444, Percent_Identity=22.972972972973, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081915, Length=405, Percent_Identity=23.4567901234568, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786694, Length=367, Percent_Identity=24.7956403269755, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI2367353, Length=358, Percent_Identity=22.9050279329609, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=417, Percent_Identity=35.0119904076739, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17533459, Length=413, Percent_Identity=32.6876513317191, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17531343, Length=415, Percent_Identity=31.8072289156626, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17568033, Length=418, Percent_Identity=24.8803827751196, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17537453, Length=352, Percent_Identity=25.5681818181818, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=356, Percent_Identity=23.314606741573, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193208714, Length=423, Percent_Identity=24.3498817966903, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32566695, Length=423, Percent_Identity=24.3498817966903, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322892, Length=378, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667468, Length=423, Percent_Identity=36.6430260047281, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI221512776, Length=421, Percent_Identity=37.0546318289786, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24666159, Length=421, Percent_Identity=37.0546318289786, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24668806, Length=439, Percent_Identity=34.1685649202733, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21356285, Length=439, Percent_Identity=34.1685649202733, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24668802, Length=439, Percent_Identity=34.1685649202733, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI161077963, Length=412, Percent_Identity=37.1359223300971, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI281366235, Length=414, Percent_Identity=31.6425120772947, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI116007820, Length=414, Percent_Identity=31.6425120772947, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=31.6425120772947, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=31.6425120772947, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI21357367, Length=445, Percent_Identity=24.0449438202247, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651635, Length=407, Percent_Identity=24.0786240786241, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24651633, Length=407, Percent_Identity=24.0786240786241, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221331183, Length=422, Percent_Identity=23.4597156398104, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647653, Length=422, Percent_Identity=23.4597156398104, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664379, Length=422, Percent_Identity=23.4597156398104, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641993, Length=435, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641995, Length=435, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49677; Mature: 49546

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCC
>Mature Secondary Structure 
SLMRKKSVQGMLAAAQTSRGLRKELSAFDLTMLGIGAIIGTGIFVLTGTGATIAGPGLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]