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The map label for this gene is ompR [H]

Identifier: 34498562

GI number: 34498562

Start: 3394977

End: 3395690

Strand: Reverse

Name: ompR [H]

Synonym: CV_3107

Alternate gene names: 34498562

Gene position: 3395690-3394977 (Counterclockwise)

Preceding gene: 34498563

Following gene: 34498561

Centisome position: 71.47

GC content: 66.67

Gene sequence:

>714_bases
ATGTCTCAAGCTTCCCGCGTACTTATTGTCGATGACGATCCGGATCTGCGCGATCTGCTTAGCGATTATCTGAGCCGCCA
GGACATGGTTGTCTCCGCGGTGGGCGATGGCGAGGCGATGAACCGCGCCCTGGCCGAGCAATCGTTCGACATCCTGATCC
TGGACCTGATGCTGCCGGGCGCGGACGGCCTGACGCTGTGCCGCGACCTGCGCTCCCGCTCCAATATGCCCATCCTGATG
CTGACGGCGCGCGGCGACGAGCTGGACCGCATCATCGGCCTGGAAATGGGCGCCGACGACTACCTGCCCAAGCCGTTCAA
TCCGCGCGAGCTGCTGGCCCGCGTGCGCAGCATCCTGCGCCGGGTGGAGGAGCGCCGCAACAACAGCGCGCTGCGCGCCT
TGCAGTTCGGCGACTGGCGGCTGGAGCTGGGCGCCCAGCACCTGGTCGACGGCGGCGGCGTGGTGACGCCCTTGTCCGGC
GGCGAGTTCAAGCTGATGCAGGCGCTGGCCGAAAATCCGCAGCGCGTGATGTCGCGCGATCAATTGATGGAGGCGATGAA
CGGCAAGGAAGCCGGTCCGTTCGATCGCACCGTCGACGTGATGATAGGCCGCCTGCGCCGCCGCCTGGGAGACGACGCGC
GCGAGCCGCTGCTGATCAAGACCATACGCAGCGGCGGCTACATGCTGGCTTGCGAGGTGGTGCCGGTGCGATGA

Upstream 100 bases:

>100_bases
CAACCTTGAGAACGCGGGCGCCAGAAGATGGCGCCCGCGCCGTTGTCGCGCTTGCAGGCGACACCTTCGTGACCAACTCC
CGATACCTTAGGAACTGCCG

Downstream 100 bases:

>100_bases
GGCGTCTGCCTCGCACCCTGTACGGCCAGTTGTTGTTGACGCTGCTGACCAGCGTGCTGTTGGCCAACGTGATCGGCATC
GCGCTGGTGCTGACCGACCG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSQASRVLIVDDDPDLRDLLSDYLSRQDMVVSAVGDGEAMNRALAEQSFDILILDLMLPGADGLTLCRDLRSRSNMPILM
LTARGDELDRIIGLEMGADDYLPKPFNPRELLARVRSILRRVEERRNNSALRALQFGDWRLELGAQHLVDGGGVVTPLSG
GEFKLMQALAENPQRVMSRDQLMEAMNGKEAGPFDRTVDVMIGRLRRRLGDDAREPLLIKTIRSGGYMLACEVVPVR

Sequences:

>Translated_237_residues
MSQASRVLIVDDDPDLRDLLSDYLSRQDMVVSAVGDGEAMNRALAEQSFDILILDLMLPGADGLTLCRDLRSRSNMPILM
LTARGDELDRIIGLEMGADDYLPKPFNPRELLARVRSILRRVEERRNNSALRALQFGDWRLELGAQHLVDGGGVVTPLSG
GEFKLMQALAENPQRVMSRDQLMEAMNGKEAGPFDRTVDVMIGRLRRRLGDDAREPLLIKTIRSGGYMLACEVVPVR
>Mature_236_residues
SQASRVLIVDDDPDLRDLLSDYLSRQDMVVSAVGDGEAMNRALAEQSFDILILDLMLPGADGLTLCRDLRSRSNMPILML
TARGDELDRIIGLEMGADDYLPKPFNPRELLARVRSILRRVEERRNNSALRALQFGDWRLELGAQHLVDGGGVVTPLSGG
EFKLMQALAENPQRVMSRDQLMEAMNGKEAGPFDRTVDVMIGRLRRRLGDDAREPLLIKTIRSGGYMLACEVVPVR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=45.9227467811159, Blast_Score=210, Evalue=6e-56,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=38.3620689655172, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=37.9746835443038, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=38.961038961039, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=34.7639484978541, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=34.3347639484979, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=37.3913043478261, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=35.2173913043478, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=35.2422907488987, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.920704845815, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.5132743362832, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.2105263157895, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=238, Percent_Identity=34.453781512605, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=32.7868852459016, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=29.4642857142857, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26448; Mature: 26317

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQASRVLIVDDDPDLRDLLSDYLSRQDMVVSAVGDGEAMNRALAEQSFDILILDLMLPG
CCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCC
ADGLTLCRDLRSRSNMPILMLTARGDELDRIIGLEMGADDYLPKPFNPRELLARVRSILR
CCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHH
RVEERRNNSALRALQFGDWRLELGAQHLVDGGGVVTPLSGGEFKLMQALAENPQRVMSRD
HHHHHHCCHHHHHHCCCCEEEECCHHHHCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHH
QLMEAMNGKEAGPFDRTVDVMIGRLRRRLGDDAREPLLIKTIRSGGYMLACEVVPVR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECC
>Mature Secondary Structure 
SQASRVLIVDDDPDLRDLLSDYLSRQDMVVSAVGDGEAMNRALAEQSFDILILDLMLPG
CCCCEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCC
ADGLTLCRDLRSRSNMPILMLTARGDELDRIIGLEMGADDYLPKPFNPRELLARVRSILR
CCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHH
RVEERRNNSALRALQFGDWRLELGAQHLVDGGGVVTPLSGGEFKLMQALAENPQRVMSRD
HHHHHHCCHHHHHHCCCCEEEECCHHHHCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHH
QLMEAMNGKEAGPFDRTVDVMIGRLRRRLGDDAREPLLIKTIRSGGYMLACEVVPVR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]