Click here to switch to the map view.

The map label for this gene is fruK [H]

Identifier: 34498508

GI number: 34498508

Start: 3331761

End: 3332717

Strand: Direct

Name: fruK [H]

Synonym: CV_3053

Alternate gene names: 34498508

Gene position: 3331761-3332717 (Clockwise)

Preceding gene: 34498507

Following gene: 34498509

Centisome position: 70.13

GC content: 74.92

Gene sequence:

>957_bases
ATGAGCGGCGCGATACACACCGTCACCCCCAATCCGGCGCTCGACCAGACCGTGACCCTGGACGCCTTGCGGACCGGCGC
CGTCAACCTGGCGCGCGCCGCCCACGTCAACGCTGGCGGCAAGGGCGTCAACGTCGCCTCCTGCCTGGCCGACTGGGGCC
TGCCGGTCCACGCCCACGGCCTGCTGGGCCGCGACAACAGCGGCCCCTTCGAGCAGCTGTTCGCCGCCAAGCGCATAGAC
GACCGCATGCTGCGGGTGGCCGGCGCCTGCCGCGTCAACATCAAGCTGGCCGATCTCGAAACCGGCGACACCACCGACAT
CAACCTGCCCGGCCCGGAAACCGGCGAGGCCGAGCTGCAGGCGCTGGCCTCCGGCCTCGCCCATCTCGGCGCCGGCGACC
TGGCGGTGCTGGCCGGCAGCCTGCCGCCCGGCCTGCCGCGCGACGCGCTGGCCCGGCTGTGCGCGCAGCTGAAGCGGCAA
GGCGCCTGGGTGCTGGTGGACAGCAGCGGCTCGCCGCTGGCGGCCGCGCTGGCCAATCCGCCGGAGGCGCTGCCCGACTG
CGTGAAACCCAATCGCGATGAGCTGGCGCAATGGGCAGGCCGCCCGCTGCCCGGCCTGGACGACGTGGTCCGCTGCGCGC
GCGGCTTGCAGCGGATGGGCGTCGGCCGGGTGGTGGTGTCGCTGGGCGAACTGGGCGCGCTGCTGGTGGACGCCGACGCG
GCGCTGCTGGCCAGCCTGCCGCCGCAGCGGCCGCTGAGCACCGTCGGCGCCGGCGACGCGCTGGTGGCCGGCCTGGCCGC
CGCCAGAAGCCAGGGGCTGAACGCCGCGGACAGCCTGACGCTGGCGGTGGCCTTCGCCGCCGCCAAGCTGCAACGCGTCG
GCCCGCACCTGCCGCCGGAACAACAGATACGAGAGCAGGCCGCCGCCGTCAGCCTGCAAACCCTGGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
TGCTGCGCCGCCACAGCCACGCCAGGCTGCGCGAGCTGGCGGAGCAGGCGCTCGCCTGCGACAGCGCCGAGGAAGTGCGG
CAATTGCTGGAGGCGCTGGC

Downstream 100 bases:

>100_bases
GCCGCGTCCGCCCAGAAACAGGGGAAACACATGAGCATCGTCGCCATCATCCGCGCCCCGGAGCGCAGCACCCAGGCCAG
GCTGGCCGCCGAAGCGCTGC

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSGAIHTVTPNPALDQTVTLDALRTGAVNLARAAHVNAGGKGVNVASCLADWGLPVHAHGLLGRDNSGPFEQLFAAKRID
DRMLRVAGACRVNIKLADLETGDTTDINLPGPETGEAELQALASGLAHLGAGDLAVLAGSLPPGLPRDALARLCAQLKRQ
GAWVLVDSSGSPLAAALANPPEALPDCVKPNRDELAQWAGRPLPGLDDVVRCARGLQRMGVGRVVVSLGELGALLVDADA
ALLASLPPQRPLSTVGAGDALVAGLAAARSQGLNAADSLTLAVAFAAAKLQRVGPHLPPEQQIREQAAAVSLQTLAAA

Sequences:

>Translated_318_residues
MSGAIHTVTPNPALDQTVTLDALRTGAVNLARAAHVNAGGKGVNVASCLADWGLPVHAHGLLGRDNSGPFEQLFAAKRID
DRMLRVAGACRVNIKLADLETGDTTDINLPGPETGEAELQALASGLAHLGAGDLAVLAGSLPPGLPRDALARLCAQLKRQ
GAWVLVDSSGSPLAAALANPPEALPDCVKPNRDELAQWAGRPLPGLDDVVRCARGLQRMGVGRVVVSLGELGALLVDADA
ALLASLPPQRPLSTVGAGDALVAGLAAARSQGLNAADSLTLAVAFAAAKLQRVGPHLPPEQQIREQAAAVSLQTLAAA
>Mature_317_residues
SGAIHTVTPNPALDQTVTLDALRTGAVNLARAAHVNAGGKGVNVASCLADWGLPVHAHGLLGRDNSGPFEQLFAAKRIDD
RMLRVAGACRVNIKLADLETGDTTDINLPGPETGEAELQALASGLAHLGAGDLAVLAGSLPPGLPRDALARLCAQLKRQG
AWVLVDSSGSPLAAALANPPEALPDCVKPNRDELAQWAGRPLPGLDDVVRCARGLQRMGVGRVVVSLGELGALLVDADAA
LLASLPPQRPLSTVGAGDALVAGLAAARSQGLNAADSLTLAVAFAAAKLQRVGPHLPPEQQIREQAAAVSLQTLAAA

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=266, Percent_Identity=40.2255639097744, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1788017, Length=295, Percent_Identity=31.5254237288136, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32348; Mature: 32217

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAIHTVTPNPALDQTVTLDALRTGAVNLARAAHVNAGGKGVNVASCLADWGLPVHAHG
CCCCEEEECCCCCCCCCEEHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECC
LLGRDNSGPFEQLFAAKRIDDRMLRVAGACRVNIKLADLETGDTTDINLPGPETGEAELQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCEEECCCCCCCHHHHH
ALASGLAHLGAGDLAVLAGSLPPGLPRDALARLCAQLKRQGAWVLVDSSGSPLAAALANP
HHHHHHHHCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHCCC
PEALPDCVKPNRDELAQWAGRPLPGLDDVVRCARGLQRMGVGRVVVSLGELGALLVDADA
HHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCEEEECCCH
ALLASLPPQRPLSTVGAGDALVAGLAAARSQGLNAADSLTLAVAFAAAKLQRVGPHLPPE
HHHHCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
QQIREQAAAVSLQTLAAA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGAIHTVTPNPALDQTVTLDALRTGAVNLARAAHVNAGGKGVNVASCLADWGLPVHAHG
CCCEEEECCCCCCCCCEEHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECC
LLGRDNSGPFEQLFAAKRIDDRMLRVAGACRVNIKLADLETGDTTDINLPGPETGEAELQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCEEECCCCCCCHHHHH
ALASGLAHLGAGDLAVLAGSLPPGLPRDALARLCAQLKRQGAWVLVDSSGSPLAAALANP
HHHHHHHHCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHCCC
PEALPDCVKPNRDELAQWAGRPLPGLDDVVRCARGLQRMGVGRVVVSLGELGALLVDADA
HHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCEEEECCCH
ALLASLPPQRPLSTVGAGDALVAGLAAARSQGLNAADSLTLAVAFAAAKLQRVGPHLPPE
HHHHCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
QQIREQAAAVSLQTLAAA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850730; 2254279 [H]