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The map label for this gene is aroB [H]

Identifier: 34498288

GI number: 34498288

Start: 3087077

End: 3088357

Strand: Direct

Name: aroB [H]

Synonym: CV_2833

Alternate gene names: 34498288

Gene position: 3087077-3088357 (Clockwise)

Preceding gene: 34498287

Following gene: 34498289

Centisome position: 64.98

GC content: 69.63

Gene sequence:

>1281_bases
ATGACCGGAACGGATGCTCTTCGCCCTCTCTCCAACGACAGCGGAGCAGAAACCGACGACAAGCCGGACTCGCCGCGGCA
ACTGCGGCTGATCCATGACTTCAGCGTGGTCCACACCCGCGACGTCTTCGCCGCCGACAATCCCGTCCTGCTTGAAACCT
TGCGCCGCCGCGAAGCCGACAAGCGGCACCGGGTGGCGGTTTTCGTCGACGACGGCGTGTTGCGGGCCTGTCCGAAACTG
CCGCAACGCATCCGCGGCTACGCGCAAGCGCATGCGTCCCACCTGGAGATAATCGGCGAGATCGTGCCGGTGCCGGGCGG
GGAAGCCTGCAAGAACGATCCCCAGCAACTGTGGCGGCTGCTGCAGGCGCTGGCGGATCGGAATATCGACCGCCACTCCT
ACGCGCTGGCCATAGGCGGCGGCGCGGCGCTGGACGCCGTAGGCCTGGCCGCGTCGCTGTTCCATCGCGGCGTGCGCCAC
ATCCGACTGCCGTCCACGGTGCTGTCCCAGGCCGACAGCGGCGTCGGGGTCAAGAACGCCATCAACTGGAACGGCCAGAA
AAACCTGCTGGGCAGCTTCGCCGTGCCCTGGGCCGTCATCAACGACGCGGCGCTGATAGACGGTCTGCCCGCGCGCGAGA
AGCGCGCCGGCATGGCCGAGGCGGTGAAGGTGGCGCTGATCCGCGACGCGTCATTCTTCCGTTGGCTGGAGGCCCGCGCC
GACGCGCTCGCCCGCTTCGAACCCCGGGATCTGGAGCAACTGATACGACGCTCGGCGGCGCTGCACCTGCGCCAGATCAC
CCAAGGCGGCGACCCGTTCGAACAGGGTTCGGCGCGGCCGCTGGATTATGGCCACTGGATCGCCCACAAGCTGGAGCGGC
TAAGCGGCCATGCGCTGAACCACGGCGAGGCGGTGGCCATAGGCGTCGCCTGCGACGCGCGCCACTCCGTCTTGGCCGGC
CTGCTGCCGGAGGGCGGCGAAACGCGCGTCTGGCAGCTGCTGCGCGCGCTGGGCTTCGAGCTATGGCACGAGCAACTGCT
GGCCAGGGACGAGCACGGCCGGCTGGCGCTGCTGCGCGGCCTGGACGAATTCCGCGAACACCTGGGCGGCGACTTGTGCG
TGACCCTGCTGGCGGAGCTGGGGCGCGGCTGCGAAGTGGACAGCATCGCCGAGGAGCGGGTGATGCGCAGCATCCTCTGG
CTGCAACGATGCCTCGCCTCCTCCCCGGCATCCGCGCACGCGGATACCGCCGCGGCCGCCGCCTGCGGGGCCGCGCGATG
A

Upstream 100 bases:

>100_bases
GATGGCGGCGCCGCCGTTCATGCTGATCCGTTGATCCGCCCATGGCCACGCGTTCCGGCAAGCTTGCCGAAGCGCGTGGC
TTACGCACCAGGAGATGCCG

Downstream 100 bases:

>100_bases
AGCTGGCCCACCTGCCCCTGCCCGCGCACCTGTCCTATTGCACCAATATCCATGCCGGCGACAGCCTGGCCGAAGTCGAG
GCCAGCCTGGACGGCTTCCT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTGTDALRPLSNDSGAETDDKPDSPRQLRLIHDFSVVHTRDVFAADNPVLLETLRRREADKRHRVAVFVDDGVLRACPKL
PQRIRGYAQAHASHLEIIGEIVPVPGGEACKNDPQQLWRLLQALADRNIDRHSYALAIGGGAALDAVGLAASLFHRGVRH
IRLPSTVLSQADSGVGVKNAINWNGQKNLLGSFAVPWAVINDAALIDGLPAREKRAGMAEAVKVALIRDASFFRWLEARA
DALARFEPRDLEQLIRRSAALHLRQITQGGDPFEQGSARPLDYGHWIAHKLERLSGHALNHGEAVAIGVACDARHSVLAG
LLPEGGETRVWQLLRALGFELWHEQLLARDEHGRLALLRGLDEFREHLGGDLCVTLLAELGRGCEVDSIAEERVMRSILW
LQRCLASSPASAHADTAAAAACGAAR

Sequences:

>Translated_426_residues
MTGTDALRPLSNDSGAETDDKPDSPRQLRLIHDFSVVHTRDVFAADNPVLLETLRRREADKRHRVAVFVDDGVLRACPKL
PQRIRGYAQAHASHLEIIGEIVPVPGGEACKNDPQQLWRLLQALADRNIDRHSYALAIGGGAALDAVGLAASLFHRGVRH
IRLPSTVLSQADSGVGVKNAINWNGQKNLLGSFAVPWAVINDAALIDGLPAREKRAGMAEAVKVALIRDASFFRWLEARA
DALARFEPRDLEQLIRRSAALHLRQITQGGDPFEQGSARPLDYGHWIAHKLERLSGHALNHGEAVAIGVACDARHSVLAG
LLPEGGETRVWQLLRALGFELWHEQLLARDEHGRLALLRGLDEFREHLGGDLCVTLLAELGRGCEVDSIAEERVMRSILW
LQRCLASSPASAHADTAAAAACGAAR
>Mature_425_residues
TGTDALRPLSNDSGAETDDKPDSPRQLRLIHDFSVVHTRDVFAADNPVLLETLRRREADKRHRVAVFVDDGVLRACPKLP
QRIRGYAQAHASHLEIIGEIVPVPGGEACKNDPQQLWRLLQALADRNIDRHSYALAIGGGAALDAVGLAASLFHRGVRHI
RLPSTVLSQADSGVGVKNAINWNGQKNLLGSFAVPWAVINDAALIDGLPAREKRAGMAEAVKVALIRDASFFRWLEARAD
ALARFEPRDLEQLIRRSAALHLRQITQGGDPFEQGSARPLDYGHWIAHKLERLSGHALNHGEAVAIGVACDARHSVLAGL
LPEGGETRVWQLLRALGFELWHEQLLARDEHGRLALLRGLDEFREHLGGDLCVTLLAELGRGCEVDSIAEERVMRSILWL
QRCLASSPASAHADTAAAAACGAAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=240, Percent_Identity=37.0833333333333, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320332, Length=288, Percent_Identity=29.1666666666667, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 46445; Mature: 46314

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTDALRPLSNDSGAETDDKPDSPRQLRLIHDFSVVHTRDVFAADNPVLLETLRRREAD
CCCCHHCCCCCCCCCCCCCCCCCCCHHEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCC
KRHRVAVFVDDGVLRACPKLPQRIRGYAQAHASHLEIIGEIVPVPGGEACKNDPQQLWRL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHH
LQALADRNIDRHSYALAIGGGAALDAVGLAASLFHRGVRHIRLPSTVLSQADSGVGVKNA
HHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCC
INWNGQKNLLGSFAVPWAVINDAALIDGLPAREKRAGMAEAVKVALIRDASFFRWLEARA
CCCCCCHHHHHHHHCCHHHHCCHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DALARFEPRDLEQLIRRSAALHLRQITQGGDPFEQGSARPLDYGHWIAHKLERLSGHALN
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCC
HGEAVAIGVACDARHSVLAGLLPEGGETRVWQLLRALGFELWHEQLLARDEHGRLALLRG
CCCEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LDEFREHLGGDLCVTLLAELGRGCEVDSIAEERVMRSILWLQRCLASSPASAHADTAAAA
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ACGAAR
HHCCCC
>Mature Secondary Structure 
TGTDALRPLSNDSGAETDDKPDSPRQLRLIHDFSVVHTRDVFAADNPVLLETLRRREAD
CCCHHCCCCCCCCCCCCCCCCCCCHHEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCC
KRHRVAVFVDDGVLRACPKLPQRIRGYAQAHASHLEIIGEIVPVPGGEACKNDPQQLWRL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHH
LQALADRNIDRHSYALAIGGGAALDAVGLAASLFHRGVRHIRLPSTVLSQADSGVGVKNA
HHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCC
INWNGQKNLLGSFAVPWAVINDAALIDGLPAREKRAGMAEAVKVALIRDASFFRWLEARA
CCCCCCHHHHHHHHCCHHHHCCHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DALARFEPRDLEQLIRRSAALHLRQITQGGDPFEQGSARPLDYGHWIAHKLERLSGHALN
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCC
HGEAVAIGVACDARHSVLAGLLPEGGETRVWQLLRALGFELWHEQLLARDEHGRLALLRG
CCCEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LDEFREHLGGDLCVTLLAELGRGCEVDSIAEERVMRSILWLQRCLASSPASAHADTAAAA
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ACGAAR
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA