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The map label for this gene is trxB [H]

Identifier: 34498268

GI number: 34498268

Start: 3064189

End: 3065178

Strand: Direct

Name: trxB [H]

Synonym: CV_2813

Alternate gene names: 34498268

Gene position: 3064189-3065178 (Clockwise)

Preceding gene: 34498263

Following gene: 34498269

Centisome position: 64.49

GC content: 66.57

Gene sequence:

>990_bases
TTGAATTCCCACCTTTTCGACGACAGGAAAACACACATGAGCGCACCCCGTCACAGCCCTCTGCTGATTCTTGGCTCCGG
CCCGGCCGGCTACACCGCCGCCGTCTACGCCGCGCGCGCCAACCTGAAGCCGGTCGTGATCACCGGCTTGGCCCAAGGCG
GCCAGCTGATGACCACCACCGACGTGGACAACTGGCCCGCCGACGCGGAAGGCGTGCAGGGTCCGGAATTGATGCAGCGC
TTCCAGCAGCACGCCGAGCGCTTCGGCACTGAAATCCTGTTCGACCACATCCACACCACCCATCTGAGCGAGAAGCCGAT
CCGCCTGGTGGGCGACGCCGGCGAATACACCTGCGACGCGCTGATCATCGCCACCGGCGCCTCCGCCCAATACCTGGGCC
TGCCGTCGGAAGAGGCCTTCGCCGGCAAGGGCGTGTCCGCCTGCGCCACCTGCGACGGCTTCTTCTACCGCAACCAGGAC
GTGGCGGTGGTGGGCGGCGGCAACACCGCGGTCGAAGAGGCGCTGTACCTGGCCAATATCGCCAGGCACGTCACCCTGAT
CCACCGCCGCGACACCTTCCGCGCCGAGAAGATCCTGGTCGACAAGCTGATGAGCCGCGTCGCCGAAGGCAAGATCAGCC
TGAAGCTGAACGCCACGCTGGACGAAGTGCTGGGCGACGACAGCGGCGTGACCGGCGTGCGCGTCAAACTGAACGACGGC
GGCAGCGAAAACCTGGCGCTGACCGGCGTGTTCATCGCCATCGGCCACAAGCCCAACACCGACATCTTCAAAGGCCAGCT
GGAAATGGACAGCACCGGCTACCTGATCACCAAGGGCGGCCGCGACGGCAACGCCACCCTCACCAGCATCGACGGCGTGT
TCGCCGCCGGCGACGTGCAGGACCACATCTACCGCCAGGCCGTGACCAGCGCCGCCTCCGGCTGCCAGGCCGCCCTGGAC
GCCGAGCGCTACCTCGACAGCCTGAAGTAA

Upstream 100 bases:

>100_bases
GCGTCCATACCCCCACCTCCTCAAAATGCTGCAAAGTGCATCACAATCTGCAGTGTAGCGCCATGCCGGCCAGCGGCATA
GCAAAACTGTTAGAATGTGA

Downstream 100 bases:

>100_bases
GCGCCGGAAGTCCTGCATCATGAAGACCTTCAAGGACACTCTGAAGGGACTTCGCCAGACGCTGCGCCAGGCCGCCCCGC
CGCGGGCGGCCGCGCCGCAG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNSHLFDDRKTHMSAPRHSPLLILGSGPAGYTAAVYAARANLKPVVITGLAQGGQLMTTTDVDNWPADAEGVQGPELMQR
FQQHAERFGTEILFDHIHTTHLSEKPIRLVGDAGEYTCDALIIATGASAQYLGLPSEEAFAGKGVSACATCDGFFYRNQD
VAVVGGGNTAVEEALYLANIARHVTLIHRRDTFRAEKILVDKLMSRVAEGKISLKLNATLDEVLGDDSGVTGVRVKLNDG
GSENLALTGVFIAIGHKPNTDIFKGQLEMDSTGYLITKGGRDGNATLTSIDGVFAAGDVQDHIYRQAVTSAASGCQAALD
AERYLDSLK

Sequences:

>Translated_329_residues
MNSHLFDDRKTHMSAPRHSPLLILGSGPAGYTAAVYAARANLKPVVITGLAQGGQLMTTTDVDNWPADAEGVQGPELMQR
FQQHAERFGTEILFDHIHTTHLSEKPIRLVGDAGEYTCDALIIATGASAQYLGLPSEEAFAGKGVSACATCDGFFYRNQD
VAVVGGGNTAVEEALYLANIARHVTLIHRRDTFRAEKILVDKLMSRVAEGKISLKLNATLDEVLGDDSGVTGVRVKLNDG
GSENLALTGVFIAIGHKPNTDIFKGQLEMDSTGYLITKGGRDGNATLTSIDGVFAAGDVQDHIYRQAVTSAASGCQAALD
AERYLDSLK
>Mature_329_residues
MNSHLFDDRKTHMSAPRHSPLLILGSGPAGYTAAVYAARANLKPVVITGLAQGGQLMTTTDVDNWPADAEGVQGPELMQR
FQQHAERFGTEILFDHIHTTHLSEKPIRLVGDAGEYTCDALIIATGASAQYLGLPSEEAFAGKGVSACATCDGFFYRNQD
VAVVGGGNTAVEEALYLANIARHVTLIHRRDTFRAEKILVDKLMSRVAEGKISLKLNATLDEVLGDDSGVTGVRVKLNDG
GSENLALTGVFIAIGHKPNTDIFKGQLEMDSTGYLITKGGRDGNATLTSIDGVFAAGDVQDHIYRQAVTSAASGCQAALD
AERYLDSLK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=68.2389937106918, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI87081763, Length=316, Percent_Identity=32.5949367088608, Blast_Score=142, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6321898, Length=330, Percent_Identity=45.4545454545455, Blast_Score=268, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6320560, Length=326, Percent_Identity=45.0920245398773, Blast_Score=265, Evalue=9e-72,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35062; Mature: 35062

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHLFDDRKTHMSAPRHSPLLILGSGPAGYTAAVYAARANLKPVVITGLAQGGQLMTTT
CCCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHEEEEHHCCCCEEEEEEECCCCEEEEEC
DVDNWPADAEGVQGPELMQRFQQHAERFGTEILFDHIHTTHLSEKPIRLVGDAGEYTCDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
LIIATGASAQYLGLPSEEAFAGKGVSACATCDGFFYRNQDVAVVGGGNTAVEEALYLANI
EEEEECCCCEEECCCCCHHHCCCCCCHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHH
ARHVTLIHRRDTFRAEKILVDKLMSRVAEGKISLKLNATLDEVLGDDSGVTGVRVKLNDG
HHHHEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCCCCCEEEEEEECCC
GSENLALTGVFIAIGHKPNTDIFKGQLEMDSTGYLITKGGRDGNATLTSIDGVFAAGDVQ
CCCCEEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCEEEECCHH
DHIYRQAVTSAASGCQAALDAERYLDSLK
HHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSHLFDDRKTHMSAPRHSPLLILGSGPAGYTAAVYAARANLKPVVITGLAQGGQLMTTT
CCCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHEEEEHHCCCCEEEEEEECCCCEEEEEC
DVDNWPADAEGVQGPELMQRFQQHAERFGTEILFDHIHTTHLSEKPIRLVGDAGEYTCDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
LIIATGASAQYLGLPSEEAFAGKGVSACATCDGFFYRNQDVAVVGGGNTAVEEALYLANI
EEEEECCCCEEECCCCCHHHCCCCCCHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHH
ARHVTLIHRRDTFRAEKILVDKLMSRVAEGKISLKLNATLDEVLGDDSGVTGVRVKLNDG
HHHHEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHCCCCCCCEEEEEEECCC
GSENLALTGVFIAIGHKPNTDIFKGQLEMDSTGYLITKGGRDGNATLTSIDGVFAAGDVQ
CCCCEEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCEEEECCHH
DHIYRQAVTSAASGCQAALDAERYLDSLK
HHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]