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The map label for this gene is ampH [H]

Identifier: 34498263

GI number: 34498263

Start: 3060184

End: 3061500

Strand: Direct

Name: ampH [H]

Synonym: CV_2808

Alternate gene names: 34498263

Gene position: 3060184-3061500 (Clockwise)

Preceding gene: 34498262

Following gene: 34498268

Centisome position: 64.41

GC content: 68.19

Gene sequence:

>1317_bases
ATGAGAATTCTCCCCCTGCTAAGCCTCGGCCTGCCCCTGTTTACTACCCTGGCGCAGGCCGCCGAGCAACCGGCCGAGTC
CCCGATAGACCGCTACGGCCAGCAGATTTTCAAGAGCAGCAGGGCAGTCGGCATGACCATGGTGGTGATAGACAAGCGGC
AGGTCCAGATGCGTTTCTACGGCGAGACCCGTTCCGGCAACCGCCAGGCTCCGAACGCGGACTCGCTGGTGCGCATCGCC
AGCATCAGCAAGGCCATGACCGGCGAAGTGCTGACCGCGCTGACGCTGGACAAGAAAGTGAAGCTGGACGACCCGCTGCA
GAAATACGCGCCAGCCGGCGTCACCCTGCCGCCGGCGGGACAGTCGATCACCCTGCTCAACCTCGCCACCCATACCAGCG
GCGTGCCGCGCGAGATGCCGGGCGAAAAGCCCAAGGACACGCCCGTCTTCGTCTGGCCCAATGTCCAGCAACGCTGGAGC
TGGCTGTCCGGCACCAAGAACAAGCTCGCCCCCGGCCAGCGCGCCCAGTATTCCAACCTGGGCTTCGACCTGCTGGCCGA
TGCGCTGTCCCGCGCCGCCGGCAAACCCTATCCCGTGCTGTTCCGGGAAAAGATCACCGCCCCGCTGGGCATGAAGGACA
CCACCTTCACCCCCACTCCCGCCCAGTGCGCGCGGCTGATGGAAGGCTACGGCGCCAGCCCCTGCGTGGACACCACCGCG
GCGATAGGCAGCGGCGGCATCTACTCCACGCCGCGCGACATGCAGCGCTGGCTGCAGGAGCTGCTCTACCCGCAGAACGA
GGCGAGGCGCCAGTTGCGCGACCAGACCCTGCGCATGCACTTCCAGCGCGCCGACCTGAACAGCCTGCGCGGCATGGACG
TGGCCGGACAGGCCGACCAGCTGGGCCTGGCCTGGGTAAGGATGGAGCCTGGTCCGAACGCGCCGGAAATCATCCAGAAA
ACGGCCGGCGGCGGCGGCTTCCTCGGTTACGCGGCGCTGGCGCCGCGCAACGACGTGGCGGTATGGGTGGGCCTCACCCG
CAGCGGCGGCACTCACTACCAGAGCCTGAGCAACGGCGTCAACAAGCTGGTGGCCGAACTCAGCGGCTACAAGCCGATTG
CCGCGCCGATGCCCAAGCCCACGCTGGCCAAAACCAAGGCCGCCCGCGGCAAGGCGGCGCTCGCCCAGGCCAAGCCGGCC
GCGCCGCGCGCGAAAAAGGCCGCGCGGAAAGCCGCCGGCCCCAAGACTGCCGCCGCGAAAGCCGGCGCCAAGAAGAAAGC
CCGCCTGGTCAAGACCTCGGCACACCGGGCGCAGTGA

Upstream 100 bases:

>100_bases
AATTAGCAATCTTTCCGTACCGTTTCGGCCAAAGCGGCAATACAATGCAGCGCAAAGATTCATCGGCGCCGCCCGCGCCC
AACAGCAACACGGAACAATA

Downstream 100 bases:

>100_bases
GCGCGAAGCGCGCGATCTCGTCCTTGCGCATGAATCGCACGCCCGGATGGCTCTGGGCGTAGCGGATGAAGGTCTCCAGC
GCCCTCACCCGCGCCGGCGT

Product: beta-lactam binding protein AmpH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRILPLLSLGLPLFTTLAQAAEQPAESPIDRYGQQIFKSSRAVGMTMVVIDKRQVQMRFYGETRSGNRQAPNADSLVRIA
SISKAMTGEVLTALTLDKKVKLDDPLQKYAPAGVTLPPAGQSITLLNLATHTSGVPREMPGEKPKDTPVFVWPNVQQRWS
WLSGTKNKLAPGQRAQYSNLGFDLLADALSRAAGKPYPVLFREKITAPLGMKDTTFTPTPAQCARLMEGYGASPCVDTTA
AIGSGGIYSTPRDMQRWLQELLYPQNEARRQLRDQTLRMHFQRADLNSLRGMDVAGQADQLGLAWVRMEPGPNAPEIIQK
TAGGGGFLGYAALAPRNDVAVWVGLTRSGGTHYQSLSNGVNKLVAELSGYKPIAAPMPKPTLAKTKAARGKAALAQAKPA
APRAKKAARKAAGPKTAAAKAGAKKKARLVKTSAHRAQ

Sequences:

>Translated_438_residues
MRILPLLSLGLPLFTTLAQAAEQPAESPIDRYGQQIFKSSRAVGMTMVVIDKRQVQMRFYGETRSGNRQAPNADSLVRIA
SISKAMTGEVLTALTLDKKVKLDDPLQKYAPAGVTLPPAGQSITLLNLATHTSGVPREMPGEKPKDTPVFVWPNVQQRWS
WLSGTKNKLAPGQRAQYSNLGFDLLADALSRAAGKPYPVLFREKITAPLGMKDTTFTPTPAQCARLMEGYGASPCVDTTA
AIGSGGIYSTPRDMQRWLQELLYPQNEARRQLRDQTLRMHFQRADLNSLRGMDVAGQADQLGLAWVRMEPGPNAPEIIQK
TAGGGGFLGYAALAPRNDVAVWVGLTRSGGTHYQSLSNGVNKLVAELSGYKPIAAPMPKPTLAKTKAARGKAALAQAKPA
APRAKKAARKAAGPKTAAAKAGAKKKARLVKTSAHRAQ
>Mature_438_residues
MRILPLLSLGLPLFTTLAQAAEQPAESPIDRYGQQIFKSSRAVGMTMVVIDKRQVQMRFYGETRSGNRQAPNADSLVRIA
SISKAMTGEVLTALTLDKKVKLDDPLQKYAPAGVTLPPAGQSITLLNLATHTSGVPREMPGEKPKDTPVFVWPNVQQRWS
WLSGTKNKLAPGQRAQYSNLGFDLLADALSRAAGKPYPVLFREKITAPLGMKDTTFTPTPAQCARLMEGYGASPCVDTTA
AIGSGGIYSTPRDMQRWLQELLYPQNEARRQLRDQTLRMHFQRADLNSLRGMDVAGQADQLGLAWVRMEPGPNAPEIIQK
TAGGGGFLGYAALAPRNDVAVWVGLTRSGGTHYQSLSNGVNKLVAELSGYKPIAAPMPKPTLAKTKAARGKAALAQAKPA
APRAKKAARKAAGPKTAAAKAGAKKKARLVKTSAHRAQ

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI239747261, Length=265, Percent_Identity=29.0566037735849, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI239752721, Length=265, Percent_Identity=29.0566037735849, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI239741085, Length=265, Percent_Identity=29.0566037735849, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1786574, Length=364, Percent_Identity=53.8461538461538, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1790593, Length=347, Percent_Identity=23.6311239193084, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 47096; Mature: 47096

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILPLLSLGLPLFTTLAQAAEQPAESPIDRYGQQIFKSSRAVGMTMVVIDKRQVQMRFY
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEE
GETRSGNRQAPNADSLVRIASISKAMTGEVLTALTLDKKVKLDDPLQKYAPAGVTLPPAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCC
QSITLLNLATHTSGVPREMPGEKPKDTPVFVWPNVQQRWSWLSGTKNKLAPGQRAQYSNL
CEEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCHHHCC
GFDLLADALSRAAGKPYPVLFREKITAPLGMKDTTFTPTPAQCARLMEGYGASPCVDTTA
CHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
AIGSGGIYSTPRDMQRWLQELLYPQNEARRQLRDQTLRMHFQRADLNSLRGMDVAGQADQ
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LGLAWVRMEPGPNAPEIIQKTAGGGGFLGYAALAPRNDVAVWVGLTRSGGTHYQSLSNGV
CCEEEEEECCCCCCHHHHHHCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHH
NKLVAELSGYKPIAAPMPKPTLAKTKAARGKAALAQAKPAAPRAKKAARKAAGPKTAAAK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHCCCCHHHHH
AGAKKKARLVKTSAHRAQ
CCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILPLLSLGLPLFTTLAQAAEQPAESPIDRYGQQIFKSSRAVGMTMVVIDKRQVQMRFY
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEE
GETRSGNRQAPNADSLVRIASISKAMTGEVLTALTLDKKVKLDDPLQKYAPAGVTLPPAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCC
QSITLLNLATHTSGVPREMPGEKPKDTPVFVWPNVQQRWSWLSGTKNKLAPGQRAQYSNL
CEEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCHHHCC
GFDLLADALSRAAGKPYPVLFREKITAPLGMKDTTFTPTPAQCARLMEGYGASPCVDTTA
CHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
AIGSGGIYSTPRDMQRWLQELLYPQNEARRQLRDQTLRMHFQRADLNSLRGMDVAGQADQ
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LGLAWVRMEPGPNAPEIIQKTAGGGGFLGYAALAPRNDVAVWVGLTRSGGTHYQSLSNGV
CCEEEEEECCCCCCHHHHHHCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHH
NKLVAELSGYKPIAAPMPKPTLAKTKAARGKAALAQAKPAAPRAKKAARKAAGPKTAAAK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHCCCCHHHHH
AGAKKKARLVKTSAHRAQ
CCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]