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The map label for this gene is dipZ [H]

Identifier: 34497808

GI number: 34497808

Start: 2539612

End: 2541402

Strand: Reverse

Name: dipZ [H]

Synonym: CV_2353

Alternate gene names: 34497808

Gene position: 2541402-2539612 (Counterclockwise)

Preceding gene: 34497818

Following gene: 34497807

Centisome position: 53.49

GC content: 68.96

Gene sequence:

>1791_bases
GTGCAAGCATACCTCCATTCGTTTTACCGATCGGCCTGGCTATGGCTGGCGTCCGTGATCGCCTGTCTCGGCCTGGCCCT
GCCCGCGCACGCGGTCAACCAGGACGACCTGCTCCCGCCGGAGCAGGCTTTCGCCGCCCAGGTCAGCCGCAGCGGCGACC
AGCTCCAGCTGACGCTGGAGGTCGCGCCCGGATACTACCTGTACCGCGACCGCATCAGCATCAGCACCACGCCCGCCGAC
CTGGCCGGCAAGCCGACGCTGCCCGCCGCCCAGGAAAAAAATGACCCTTACTTCGGCAAGCAGCAGATTTACCATGGCAA
GCAGCTGATCACCATCCCGCTGGCCGCCGGCGCGCCGGCCGACTTCCAGCTGAACGTGAAGCTGCAAGGCTGCGCCGAAG
CCGGCGTCTGCTACCCGCCTTACACCCACAAGCTGAAGGTGGGACAGGCCGGCGCCGCGGGCAACAAGCTCAGCGCCTGG
ACGGAGGTCGACTCGTCGGGAAAAGCTTCGGCCGGTAACAGCGAGTTGGCCGCCAGGGGTTGGCTGGCCACACTGGGCAC
CTTCCTGCTGGCGGGTCTGGGCATGGCGTTCACCGCCTGCATGTACCCGCTGCTGCCCATCGTTTCATCGCTGATTGCCG
GCCAAGGCGCAACCCTCAGCCGCGGCCGCGGTTTCCTGCTGTCCCTGCTTTACGTGCAAGGCCTGGCGCTCACCTACACC
GCCGTCGGCGTCGTCGCCGGGCTGACCGGCTCGCTGCTGACCGTATGGCTGCAGCAGCCGGCGGTGGTGCTGTCCGCCAG
CGCGCTGATGGTGGTGTTCGCGCTATCCATGTTCGACCTGTTCTCCATCCAGTTGCCCAGCGCCCTGCAGTCCCGCCTGG
CCGACACCTCCAACCGGCTCACCGGCGGCAAGGCCGCCACCGTGTTTCTGATGGGCGCGCTGTCGGCGCTGATCATCGGC
CCCTGCGTGGCCCCGCCGCTGGCCTTGGCGCTGGGCTATATCGGCAGCACCGGCGACGCCGTGCTGGGCGGCGCGGCGCT
GTATGCGATGGCCATGGGCCTGGGCCTGCCGCTGATCGCCATCGGCACCTTCGGCGGCCACGTGCTGCCGCGCGCCGGCC
ACTGGATGAAGGCGGTGAAGTCCGCGTTCGGCGTGGTGATGCTGGGCCTCGCCATCTGGCTGGCCACGCCTTTCCTGCCG
CCGCCGCTGGTGATGCTGCTGTGGGCGGCGCTGCTGATCGGCTCGGCGGTGTTTCTCGGCGCCTTCGACAGCCTGTCGTC
CGCCACCAAGGCCAGCGCGCGCCTGGGCAAGGCGCTGGGCCTGCTGCTGTTCCTGCTGGGCGGCGCCCAGCTGGTCGGCC
TCTTGTCCGGCGCCGACAACCCGCGCTATCCGCTGAAGCTGCTCGCCGCCAGCAGCGCCGAGGGCGCCGTTCAGCAGCAT
TTCCAGCCGATCCGTTCGAGCGCGGAACTGGACGCCAAGCTGGCCGAGGCCAAGGCCGCCGGCAAGCCGCTGCTGCTGGA
CTTCTACGCCGACTGGTGCGTGGCCTGCAAGGAAATGGAGGCCGACGTCTTCCCGCAGCAACAGGCGGCGGCGCAGATGC
AGCGCTTCGTGTTGCTGCGCGCCGACGTCACCGCCAACACGCCCGAGCACCAGGCGCTGCTCAAGCGCTTCGGCTTGTTC
GGCCCGCCGGGCATCATCCTGTTCGACAGCCAATCCCGCGAAAGCAACCGCGTGGTCGGCTACACCCCCGCCGACGCATT
TGCCCGCGAGCTGGCCAAGGTGGCAAACTAG

Upstream 100 bases:

>100_bases
ATGCAATTTGATGCATATTGCATCACGCATCGTAAAAACGGAACCGCAAACCGTTTACATCGTCACAGTTTCATCGCCAA
CCGCAAAGAAGAGTCTGCAC

Downstream 100 bases:

>100_bases
CGCCGTATCCGGCCGGCGCCATCGCGCCGGCCGCCATTTCCGCCACCTAGATCGGACGCCTCCATGCCGCCCCTCCCCAA
CGCTTTTCCCAATGTCAGCA

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MQAYLHSFYRSAWLWLASVIACLGLALPAHAVNQDDLLPPEQAFAAQVSRSGDQLQLTLEVAPGYYLYRDRISISTTPAD
LAGKPTLPAAQEKNDPYFGKQQIYHGKQLITIPLAAGAPADFQLNVKLQGCAEAGVCYPPYTHKLKVGQAGAAGNKLSAW
TEVDSSGKASAGNSELAARGWLATLGTFLLAGLGMAFTACMYPLLPIVSSLIAGQGATLSRGRGFLLSLLYVQGLALTYT
AVGVVAGLTGSLLTVWLQQPAVVLSASALMVVFALSMFDLFSIQLPSALQSRLADTSNRLTGGKAATVFLMGALSALIIG
PCVAPPLALALGYIGSTGDAVLGGAALYAMAMGLGLPLIAIGTFGGHVLPRAGHWMKAVKSAFGVVMLGLAIWLATPFLP
PPLVMLLWAALLIGSAVFLGAFDSLSSATKASARLGKALGLLLFLLGGAQLVGLLSGADNPRYPLKLLAASSAEGAVQQH
FQPIRSSAELDAKLAEAKAAGKPLLLDFYADWCVACKEMEADVFPQQQAAAQMQRFVLLRADVTANTPEHQALLKRFGLF
GPPGIILFDSQSRESNRVVGYTPADAFARELAKVAN

Sequences:

>Translated_596_residues
MQAYLHSFYRSAWLWLASVIACLGLALPAHAVNQDDLLPPEQAFAAQVSRSGDQLQLTLEVAPGYYLYRDRISISTTPAD
LAGKPTLPAAQEKNDPYFGKQQIYHGKQLITIPLAAGAPADFQLNVKLQGCAEAGVCYPPYTHKLKVGQAGAAGNKLSAW
TEVDSSGKASAGNSELAARGWLATLGTFLLAGLGMAFTACMYPLLPIVSSLIAGQGATLSRGRGFLLSLLYVQGLALTYT
AVGVVAGLTGSLLTVWLQQPAVVLSASALMVVFALSMFDLFSIQLPSALQSRLADTSNRLTGGKAATVFLMGALSALIIG
PCVAPPLALALGYIGSTGDAVLGGAALYAMAMGLGLPLIAIGTFGGHVLPRAGHWMKAVKSAFGVVMLGLAIWLATPFLP
PPLVMLLWAALLIGSAVFLGAFDSLSSATKASARLGKALGLLLFLLGGAQLVGLLSGADNPRYPLKLLAASSAEGAVQQH
FQPIRSSAELDAKLAEAKAAGKPLLLDFYADWCVACKEMEADVFPQQQAAAQMQRFVLLRADVTANTPEHQALLKRFGLF
GPPGIILFDSQSRESNRVVGYTPADAFARELAKVAN
>Mature_596_residues
MQAYLHSFYRSAWLWLASVIACLGLALPAHAVNQDDLLPPEQAFAAQVSRSGDQLQLTLEVAPGYYLYRDRISISTTPAD
LAGKPTLPAAQEKNDPYFGKQQIYHGKQLITIPLAAGAPADFQLNVKLQGCAEAGVCYPPYTHKLKVGQAGAAGNKLSAW
TEVDSSGKASAGNSELAARGWLATLGTFLLAGLGMAFTACMYPLLPIVSSLIAGQGATLSRGRGFLLSLLYVQGLALTYT
AVGVVAGLTGSLLTVWLQQPAVVLSASALMVVFALSMFDLFSIQLPSALQSRLADTSNRLTGGKAATVFLMGALSALIIG
PCVAPPLALALGYIGSTGDAVLGGAALYAMAMGLGLPLIAIGTFGGHVLPRAGHWMKAVKSAFGVVMLGLAIWLATPFLP
PPLVMLLWAALLIGSAVFLGAFDSLSSATKASARLGKALGLLLFLLGGAQLVGLLSGADNPRYPLKLLAASSAEGAVQQH
FQPIRSSAELDAKLAEAKAAGKPLLLDFYADWCVACKEMEADVFPQQQAAAQMQRFVLLRADVTANTPEHQALLKRFGLF
GPPGIILFDSQSRESNRVVGYTPADAFARELAKVAN

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=561, Percent_Identity=37.9679144385027, Blast_Score=340, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 62396; Mature: 62396

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAYLHSFYRSAWLWLASVIACLGLALPAHAVNQDDLLPPEQAFAAQVSRSGDQLQLTLE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
VAPGYYLYRDRISISTTPADLAGKPTLPAAQEKNDPYFGKQQIYHGKQLITIPLAAGAPA
ECCCEEEEECCEEEECCCHHCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCC
DFQLNVKLQGCAEAGVCYPPYTHKLKVGQAGAAGNKLSAWTEVDSSGKASAGNSELAARG
CEEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
WLATLGTFLLAGLGMAFTACMYPLLPIVSSLIAGQGATLSRGRGFLLSLLYVQGLALTYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AVGVVAGLTGSLLTVWLQQPAVVLSASALMVVFALSMFDLFSIQLPSALQSRLADTSNRL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
TGGKAATVFLMGALSALIIGPCVAPPLALALGYIGSTGDAVLGGAALYAMAMGLGLPLIA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHEE
IGTFGGHVLPRAGHWMKAVKSAFGVVMLGLAIWLATPFLPPPLVMLLWAALLIGSAVFLG
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AFDSLSSATKASARLGKALGLLLFLLGGAQLVGLLSGADNPRYPLKLLAASSAEGAVQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHH
FQPIRSSAELDAKLAEAKAAGKPLLLDFYADWCVACKEMEADVFPQQQAAAQMQRFVLLR
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEE
ADVTANTPEHQALLKRFGLFGPPGIILFDSQSRESNRVVGYTPADAFARELAKVAN
ECCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MQAYLHSFYRSAWLWLASVIACLGLALPAHAVNQDDLLPPEQAFAAQVSRSGDQLQLTLE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
VAPGYYLYRDRISISTTPADLAGKPTLPAAQEKNDPYFGKQQIYHGKQLITIPLAAGAPA
ECCCEEEEECCEEEECCCHHCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCC
DFQLNVKLQGCAEAGVCYPPYTHKLKVGQAGAAGNKLSAWTEVDSSGKASAGNSELAARG
CEEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
WLATLGTFLLAGLGMAFTACMYPLLPIVSSLIAGQGATLSRGRGFLLSLLYVQGLALTYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AVGVVAGLTGSLLTVWLQQPAVVLSASALMVVFALSMFDLFSIQLPSALQSRLADTSNRL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
TGGKAATVFLMGALSALIIGPCVAPPLALALGYIGSTGDAVLGGAALYAMAMGLGLPLIA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHEE
IGTFGGHVLPRAGHWMKAVKSAFGVVMLGLAIWLATPFLPPPLVMLLWAALLIGSAVFLG
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AFDSLSSATKASARLGKALGLLLFLLGGAQLVGLLSGADNPRYPLKLLAASSAEGAVQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHH
FQPIRSSAELDAKLAEAKAAGKPLLLDFYADWCVACKEMEADVFPQQQAAAQMQRFVLLR
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEE
ADVTANTPEHQALLKRFGLFGPPGIILFDSQSRESNRVVGYTPADAFARELAKVAN
ECCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]