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The map label for this gene is cdsA [H]

Identifier: 34497656

GI number: 34497656

Start: 2371319

End: 2372125

Strand: Direct

Name: cdsA [H]

Synonym: CV_2201

Alternate gene names: 34497656

Gene position: 2371319-2372125 (Clockwise)

Preceding gene: 34497655

Following gene: 34497657

Centisome position: 49.91

GC content: 68.03

Gene sequence:

>807_bases
ATGCTGATAACGCGAATTCTGACCGCGCTCGTATTGCTGCCGCTGATGCTGGCGGCGCTTTTCCTGTTTCCCGCCGCGGC
CTGGGCGGGGTTTTCCTGGTTGATCGTCGTGCTGGCCCTGTGGGAGTACACTCGCATGGTCGGGATGTCGCTGCCGCGTC
AGGCATGCTACCTTGCGCTGTCCTCGCTGTTCGCCGCCGCGGCCTGGTTCGGCCACTGGCGGATGCAGGGCGCCGAGCAT
GGCGCCGTGCTGGCGCTGTGGCTGCTGCTGGTGCCGGCCTGGCTGGCCAAGCGCTGGAAAATGCCGTCCGGCCTGACTGC
CTGGCTGCTGGGCTGGGCGCTGATGCTGCCGGCTTGGTTCGCCTTTCTTGAGTGGCGCCCGAACGCCTCCGCGCGCGACG
CGCTGGCGCTGTTGGCCGTGATGGGCCTGGTGTGGGTGGCCGACGTGGCGGCCTATTTCTCCGGCAAGGCCTTCGGGCGG
CGCAAGCTGGCGCCGGCCATCAGTCCCGGCAAGAGCTGGGAGGGCGTGTACGGCGCCGTCGTCTGCGTGGCGGTCTATGT
CGCGCTGGTCGATCATTTCGGCTGGCTGGACATCAAGCTGCCGTTGTGGGGCCTGTTGCTGCTGGCGCTGCCGTTGACCG
CGGTCAGCGTGTGCGGCGACCTGCTGGAGTCCTGGTTCAAGCGCTCCGCCGGCATCAAGGACAGCAGCCGTCTGCTGCCG
GGCCATGGCGGCGTGTATGACCGAATCGACAGCCTGATCGCCGTATTGGCGGTCAGCAACGCCCTGCGCGCGCTGGGCGG
CATGTAA

Upstream 100 bases:

>100_bases
CTGCAGGAGGCGATCCACTCCTACTGGCAGCGTGAGCGCCGCTTTGGCCGCACCAGCGAGCAATTGCCCGAACACCTGCG
TCGAGACAAGCTCTGATCTC

Downstream 100 bases:

>100_bases
TTCTGGAAACATAGCAATGACCAAACCTCAGGGTATTGCCGTACTGGGGGCTACTGGCAGCGTGGGCTGCAACACGCTGG
ATGTGGTCGCCCGCCATCCG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLITRILTALVLLPLMLAALFLFPAAAWAGFSWLIVVLALWEYTRMVGMSLPRQACYLALSSLFAAAAWFGHWRMQGAEH
GAVLALWLLLVPAWLAKRWKMPSGLTAWLLGWALMLPAWFAFLEWRPNASARDALALLAVMGLVWVADVAAYFSGKAFGR
RKLAPAISPGKSWEGVYGAVVCVAVYVALVDHFGWLDIKLPLWGLLLLALPLTAVSVCGDLLESWFKRSAGIKDSSRLLP
GHGGVYDRIDSLIAVLAVSNALRALGGM

Sequences:

>Translated_268_residues
MLITRILTALVLLPLMLAALFLFPAAAWAGFSWLIVVLALWEYTRMVGMSLPRQACYLALSSLFAAAAWFGHWRMQGAEH
GAVLALWLLLVPAWLAKRWKMPSGLTAWLLGWALMLPAWFAFLEWRPNASARDALALLAVMGLVWVADVAAYFSGKAFGR
RKLAPAISPGKSWEGVYGAVVCVAVYVALVDHFGWLDIKLPLWGLLLLALPLTAVSVCGDLLESWFKRSAGIKDSSRLLP
GHGGVYDRIDSLIAVLAVSNALRALGGM
>Mature_268_residues
MLITRILTALVLLPLMLAALFLFPAAAWAGFSWLIVVLALWEYTRMVGMSLPRQACYLALSSLFAAAAWFGHWRMQGAEH
GAVLALWLLLVPAWLAKRWKMPSGLTAWLLGWALMLPAWFAFLEWRPNASARDALALLAVMGLVWVADVAAYFSGKAFGR
RKLAPAISPGKSWEGVYGAVVCVAVYVALVDHFGWLDIKLPLWGLLLLALPLTAVSVCGDLLESWFKRSAGIKDSSRLLP
GHGGVYDRIDSLIAVLAVSNALRALGGM

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=289, Percent_Identity=34.6020761245675, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787677, Length=106, Percent_Identity=45.2830188679245, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29231; Mature: 29231

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITRILTALVLLPLMLAALFLFPAAAWAGFSWLIVVLALWEYTRMVGMSLPRQACYLAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SSLFAAAAWFGHWRMQGAEHGAVLALWLLLVPAWLAKRWKMPSGLTAWLLGWALMLPAWF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AFLEWRPNASARDALALLAVMGLVWVADVAAYFSGKAFGRRKLAPAISPGKSWEGVYGAV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHCCCCCCCCCCCCHHHHHH
VCVAVYVALVDHFGWLDIKLPLWGLLLLALPLTAVSVCGDLLESWFKRSAGIKDSSRLLP
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GHGGVYDRIDSLIAVLAVSNALRALGGM
CCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLITRILTALVLLPLMLAALFLFPAAAWAGFSWLIVVLALWEYTRMVGMSLPRQACYLAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SSLFAAAAWFGHWRMQGAEHGAVLALWLLLVPAWLAKRWKMPSGLTAWLLGWALMLPAWF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AFLEWRPNASARDALALLAVMGLVWVADVAAYFSGKAFGRRKLAPAISPGKSWEGVYGAV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHCCCCCCCCCCCCHHHHHH
VCVAVYVALVDHFGWLDIKLPLWGLLLLALPLTAVSVCGDLLESWFKRSAGIKDSSRLLP
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GHGGVYDRIDSLIAVLAVSNALRALGGM
CCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]