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The map label for this gene is iorA [H]

Identifier: 34497128

GI number: 34497128

Start: 1813088

End: 1813540

Strand: Direct

Name: iorA [H]

Synonym: CV_1673

Alternate gene names: 34497128

Gene position: 1813088-1813540 (Clockwise)

Preceding gene: 34497127

Following gene: 34497129

Centisome position: 38.16

GC content: 67.11

Gene sequence:

>453_bases
ATGAAGGTTTCCATCAACGGCAAGGCGGTGGAGCTCGGCTCCTCCCCCGACACGCCCCTGCTGTGGGCATTGCGCGACGA
GCTGGGCCTGACCGGCACCAAGTTCGGCTGCGGCGCGGCGCTGTGCGGCGCCTGTACGGTGCTGAAGAACGGCCTGCCGA
TACGTTCCTGCGTGACGCCGATTTCCTCACTGGCGGCGGACGACAGCATCACCACGGTGGAAGGCAACGCCGACAAGGTG
GCGCAGGCGGTCAAGCAGGCCTGGCACGAGCTGGACGTGGTGCAGTGCGGCTTTTGCCAGAGCGGCCAGCTGCTGGCCGC
CACCGCCTTGCTCAGCGCGAATCCTCATCCCTCCGATCAGGACATCGACCTGGCGATGAGCGGCAACCTATGCCGCTGCG
GCACCTATCCCCGCATCCGCGCGGCCATCCACGCCGCCGCCAAACTGTTGTAG

Upstream 100 bases:

>100_bases
CACCTATAGTGATTGCAGCGGCGCCTGGGCGCCGACACGCATCCGGACGGCGGCCATTCCATGGTCGTCGTCTTCTGTTT
CTCGGCTCGGGAGGCAAGGC

Downstream 100 bases:

>100_bases
GAGGCCGCGATGACGACCACCGGAGTTTCCCGCCGCGGTTTCCTGAAGATGAGCGGCGCGGTCGGCGGGGCGCTGTGCCT
GGGCTTTGTCCTGAACGAGA

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKVSINGKAVELGSSPDTPLLWALRDELGLTGTKFGCGAALCGACTVLKNGLPIRSCVTPISSLAADDSITTVEGNADKV
AQAVKQAWHELDVVQCGFCQSGQLLAATALLSANPHPSDQDIDLAMSGNLCRCGTYPRIRAAIHAAAKLL

Sequences:

>Translated_150_residues
MKVSINGKAVELGSSPDTPLLWALRDELGLTGTKFGCGAALCGACTVLKNGLPIRSCVTPISSLAADDSITTVEGNADKV
AQAVKQAWHELDVVQCGFCQSGQLLAATALLSANPHPSDQDIDLAMSGNLCRCGTYPRIRAAIHAAAKLL
>Mature_150_residues
MKVSINGKAVELGSSPDTPLLWALRDELGLTGTKFGCGAALCGACTVLKNGLPIRSCVTPISSLAADDSITTVEGNADKV
AQAVKQAWHELDVVQCGFCQSGQLLAATALLSANPHPSDQDIDLAMSGNLCRCGTYPRIRAAIHAAAKLL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=38.2165605095541, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=37.1951219512195, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1789232, Length=144, Percent_Identity=40.2777777777778, Blast_Score=88, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=155, Percent_Identity=39.3548387096774, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=155, Percent_Identity=35.4838709677419, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=34.1935483870968, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737937, Length=145, Percent_Identity=37.2413793103448, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=29.0123456790123, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15533; Mature: 15533

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSINGKAVELGSSPDTPLLWALRDELGLTGTKFGCGAALCGACTVLKNGLPIRSCVTP
CEEECCCCEEEECCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
ISSLAADDSITTVEGNADKVAQAVKQAWHELDVVQCGFCQSGQLLAATALLSANPHPSDQ
HHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHCCCCCCCCC
DIDLAMSGNLCRCGTYPRIRAAIHAAAKLL
CEEEEECCCEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVSINGKAVELGSSPDTPLLWALRDELGLTGTKFGCGAALCGACTVLKNGLPIRSCVTP
CEEECCCCEEEECCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
ISSLAADDSITTVEGNADKVAQAVKQAWHELDVVQCGFCQSGQLLAATALLSANPHPSDQ
HHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHCCCCCCCCC
DIDLAMSGNLCRCGTYPRIRAAIHAAAKLL
CEEEEECCCEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]