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The map label for this gene is gmhB [H]

Identifier: 34497112

GI number: 34497112

Start: 1796027

End: 1796566

Strand: Direct

Name: gmhB [H]

Synonym: CV_1657

Alternate gene names: 34497112

Gene position: 1796027-1796566 (Clockwise)

Preceding gene: 34497111

Following gene: 34497113

Centisome position: 37.8

GC content: 65.0

Gene sequence:

>540_bases
GTGAAGCTAGTCATTCTCGACCGCGACGGCGTGATCAACGAGGATCGCGACGATTTCGTGAAGAACACCATCGAGTGGGT
GCCCTTGGAGCACAGCCTGGAGGCGATCGCCAATCTGACCCAGTCCGGCTGGCGCGTGGTGGTGGCGACCAACCAGTCCG
GCATCGCCCGCGGCCTGTTCGACATGCATGCGCTGAACGCGATGCACGAGAAGATGCACCGCCTGGTCGGCCAGGCCGGC
GGCCGCATCGACGCGGTGGTGTTCTGTCCGCACAGCGCGGATCACGGCTGCGAGTGCCGCAAGCCGCTGCCCGGCATGGT
GCTGGAGATCGCCGAACGCTTCAACGTCAAGCTGGAAGGCCTGCCGATGATAGGCGACAGTCTGCGCGACCTGGAGGCGA
TCGCCGCCGTCGGCGGCCAGCCCATTCTGGTGAAGACCGGCAAGGGCGCCAAGACGCTGGCCAAGGGCGGCCTGCCGGAG
AGCACGCTGGTGTTCAACGACTTGTACGATGCCGCCGAGCATCTGATCAACCATCATTGA

Upstream 100 bases:

>100_bases
AGGCCCGGCTGTGCCGGGCGTTCCGCCAAGCTCGCAGTCGACGGGAATACAAACGGCGGAACGCCCCGGCGGGGCTTCCG
CCCTACTCATTGGAGAGAGC

Downstream 100 bases:

>100_bases
GGCAGAGACTGAAAGCATGATCGGCTTGTGGATACGCAATCTGTTGTACTGGGTGGTGCTCATCGTCATCACACCGGTGT
TCTTCCTGCTGCTGATGCTG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: L-histidinol; phosphate

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKLVILDRDGVINEDRDDFVKNTIEWVPLEHSLEAIANLTQSGWRVVVATNQSGIARGLFDMHALNAMHEKMHRLVGQAG
GRIDAVVFCPHSADHGCECRKPLPGMVLEIAERFNVKLEGLPMIGDSLRDLEAIAAVGGQPILVKTGKGAKTLAKGGLPE
STLVFNDLYDAAEHLINHH

Sequences:

>Translated_179_residues
MKLVILDRDGVINEDRDDFVKNTIEWVPLEHSLEAIANLTQSGWRVVVATNQSGIARGLFDMHALNAMHEKMHRLVGQAG
GRIDAVVFCPHSADHGCECRKPLPGMVLEIAERFNVKLEGLPMIGDSLRDLEAIAAVGGQPILVKTGKGAKTLAKGGLPE
STLVFNDLYDAAEHLINHH
>Mature_179_residues
MKLVILDRDGVINEDRDDFVKNTIEWVPLEHSLEAIANLTQSGWRVVVATNQSGIARGLFDMHALNAMHEKMHRLVGQAG
GRIDAVVFCPHSADHGCECRKPLPGMVLEIAERFNVKLEGLPMIGDSLRDLEAIAAVGGQPILVKTGKGAKTLAKGGLPE
STLVFNDLYDAAEHLINHH

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=175, Percent_Identity=33.1428571428571, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=26.6187050359712, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.3.15

Molecular weight: Translated: 19518; Mature: 19518

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVILDRDGVINEDRDDFVKNTIEWVPLEHSLEAIANLTQSGWRVVVATNQSGIARGLF
CEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
DMHALNAMHEKMHRLVGQAGGRIDAVVFCPHSADHGCECRKPLPGMVLEIAERFNVKLEG
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEECC
LPMIGDSLRDLEAIAAVGGQPILVKTGKGAKTLAKGGLPESTLVFNDLYDAAEHLINHH
CCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLVILDRDGVINEDRDDFVKNTIEWVPLEHSLEAIANLTQSGWRVVVATNQSGIARGLF
CEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
DMHALNAMHEKMHRLVGQAGGRIDAVVFCPHSADHGCECRKPLPGMVLEIAERFNVKLEG
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEECC
LPMIGDSLRDLEAIAAVGGQPILVKTGKGAKTLAKGGLPESTLVFNDLYDAAEHLINHH
CCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-histidinol phosphate; H2O

Specific reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]