Click here to switch to the map view.

The map label for this gene is plsC [C]

Identifier: 34497113

GI number: 34497113

Start: 1796583

End: 1797359

Strand: Direct

Name: plsC [C]

Synonym: CV_1658

Alternate gene names: 34497113

Gene position: 1796583-1797359 (Clockwise)

Preceding gene: 34497112

Following gene: 34497114

Centisome position: 37.81

GC content: 65.51

Gene sequence:

>777_bases
ATGATCGGCTTGTGGATACGCAATCTGTTGTACTGGGTGGTGCTCATCGTCATCACACCGGTGTTCTTCCTGCTGCTGAT
GCTGGCGGCGCCGCTGCCGCGCCGCAGCCGCCACGTGTTCGGGGTGACTTGGGCGATGAGCCTGCTGTGGATGCTTGAGC
ATGTGATCGGGCTGAAATACAAGGTGATCGGCGCGGAGAACATCCCGTCGGCGCCGTCGGTGATCGCGTCCAAGCACCAG
TCCGGCTGGGAAACGTTGGCGCTGCAGAAGATCTTCCCGTGGCAGGTGTATGTGGCCAAGCGCGAACTGACCTGGATCCC
GTTGTTCGGCTGGGGCCTGGTGCTGATGAACCCCATCATCATCAACCGCTCCGACCGCGCGCGCGCCAACCAGCGCCTGC
TGGACCAGGGCCTGGAGCGCAAGCGCCACGGCTTCTGGATCACCGTGTTCCCGGAGGGCACCCGCACCAAGCCGGGCGTG
GGCGGCAAGTACAAGCTGGGCGCCGCGCGCATGGCCAAGCAGTTCGACATGCCCATGGTGCCGGTGGCGCACAACGCCGG
CGAATTCTGGCCGCGCAACGCCTTCCTGAAATACCCGGGCGAGATCACCGTGGTGGTCGGCCCCGCCATCCACCCCGACA
ACGAGGCCGGTCCCGAGGCGATGATGGCCCAGGCCGAAGCCTGGATCGAAGCCCGCCAGCGCGAAATCGGCGGCGTCGGC
CCCTTTGCCCATCCCGATGAAAAACGCCAGCGTCTGGCATCGACTGCCTCTGCCTGA

Upstream 100 bases:

>100_bases
CTGGCCAAGGGCGGCCTGCCGGAGAGCACGCTGGTGTTCAACGACTTGTACGATGCCGCCGAGCATCTGATCAACCATCA
TTGAGGCAGAGACTGAAAGC

Downstream 100 bases:

>100_bases
CGGCGAGGTGCCGGTGCTGCTGACGCGCCGCGCGCGCCAGAGCATAGGCATCAAGATCCGCGACGGCGTGGTGGAACTGA
TCGCCGCGCCGGGAGTCAGT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Phosphoserine Phosphatase; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MIGLWIRNLLYWVVLIVITPVFFLLLMLAAPLPRRSRHVFGVTWAMSLLWMLEHVIGLKYKVIGAENIPSAPSVIASKHQ
SGWETLALQKIFPWQVYVAKRELTWIPLFGWGLVLMNPIIINRSDRARANQRLLDQGLERKRHGFWITVFPEGTRTKPGV
GGKYKLGAARMAKQFDMPMVPVAHNAGEFWPRNAFLKYPGEITVVVGPAIHPDNEAGPEAMMAQAEAWIEARQREIGGVG
PFAHPDEKRQRLASTASA

Sequences:

>Translated_258_residues
MIGLWIRNLLYWVVLIVITPVFFLLLMLAAPLPRRSRHVFGVTWAMSLLWMLEHVIGLKYKVIGAENIPSAPSVIASKHQ
SGWETLALQKIFPWQVYVAKRELTWIPLFGWGLVLMNPIIINRSDRARANQRLLDQGLERKRHGFWITVFPEGTRTKPGV
GGKYKLGAARMAKQFDMPMVPVAHNAGEFWPRNAFLKYPGEITVVVGPAIHPDNEAGPEAMMAQAEAWIEARQREIGGVG
PFAHPDEKRQRLASTASA
>Mature_258_residues
MIGLWIRNLLYWVVLIVITPVFFLLLMLAAPLPRRSRHVFGVTWAMSLLWMLEHVIGLKYKVIGAENIPSAPSVIASKHQ
SGWETLALQKIFPWQVYVAKRELTWIPLFGWGLVLMNPIIINRSDRARANQRLLDQGLERKRHGFWITVFPEGTRTKPGV
GGKYKLGAARMAKQFDMPMVPVAHNAGEFWPRNAFLKYPGEITVVVGPAIHPDNEAGPEAMMAQAEAWIEARQREIGGVG
PFAHPDEKRQRLASTASA

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5453718, Length=209, Percent_Identity=27.7511961722488, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI15100175, Length=209, Percent_Identity=27.7511961722488, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI6041665, Length=214, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1789395, Length=186, Percent_Identity=27.9569892473118, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=194, Percent_Identity=29.3814432989691, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=144, Percent_Identity=34.7222222222222, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24641614, Length=184, Percent_Identity=29.3478260869565, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24641612, Length=184, Percent_Identity=29.3478260869565, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 29077; Mature: 29077

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLWIRNLLYWVVLIVITPVFFLLLMLAAPLPRRSRHVFGVTWAMSLLWMLEHVIGLKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCEE
KVIGAENIPSAPSVIASKHQSGWETLALQKIFPWQVYVAKRELTWIPLFGWGLVLMNPII
EEEECCCCCCCHHHHHHHCCCCHHHHHHHHHCCEEEEEEECCEEEEEHHHHHHHHHCCCE
INRSDRARANQRLLDQGLERKRHGFWITVFPEGTRTKPGVGGKYKLGAARMAKQFDMPMV
ECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHCCCCCC
PVAHNAGEFWPRNAFLKYPGEITVVVGPAIHPDNEAGPEAMMAQAEAWIEARQREIGGVG
EEECCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PFAHPDEKRQRLASTASA
CCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIGLWIRNLLYWVVLIVITPVFFLLLMLAAPLPRRSRHVFGVTWAMSLLWMLEHVIGLKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCEE
KVIGAENIPSAPSVIASKHQSGWETLALQKIFPWQVYVAKRELTWIPLFGWGLVLMNPII
EEEECCCCCCCHHHHHHHCCCCHHHHHHHHHCCEEEEEEECCEEEEEHHHHHHHHHCCCE
INRSDRARANQRLLDQGLERKRHGFWITVFPEGTRTKPGVGGKYKLGAARMAKQFDMPMV
ECCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHCCCCCC
PVAHNAGEFWPRNAFLKYPGEITVVVGPAIHPDNEAGPEAMMAQAEAWIEARQREIGGVG
EEECCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PFAHPDEKRQRLASTASA
CCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA