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The map label for this gene is cutC

Identifier: 34496869

GI number: 34496869

Start: 1491446

End: 1492189

Strand: Direct

Name: cutC

Synonym: CV_1414

Alternate gene names: 34496869

Gene position: 1491446-1492189 (Clockwise)

Preceding gene: 34496868

Following gene: 34496870

Centisome position: 31.39

GC content: 72.18

Gene sequence:

>744_bases
ATGGACAAGATTCTGGAGATTTGCGCCGGCTCGCTGGCATCCTGCATCGCCGCTCAGGAGGGCGGCGCGCAAAGAGTGGA
GTTGTGCGACAACCTGGGCGAAGGCGGCACCACGCCGTCCTACGGCGCGCTGGCGATGGCGCGCGGACGGCTGAACATCG
CCCTGCACGCGATCATCCGTCCCCGCGGGGGCGACTTCCTGTACTCCGCGCTGGAGTTCGACGCGATGGCGCACGACGTC
GAGGTCTGCCGCAGCTTGGGCCTGGACGGCGTGGTGCTGGGCCTGCTGACCGCGGACGGCGATGTCGATGTGGCCAGAAC
CCGCCAGTTGGCCGCGCTGGCCGGGCCGATGGCGGTGACTTTCCATCGCGCCTTCGACCTGGCGCGCGAGCCGGAGCAGG
CGCTGGAGGATGTGATCGCCGCCGGCTGCAGCCGCTTGCTCAGTTCCGGCCAGGCGGCCAGCGCGCCCGAAGGCGCGGCC
CTGTTGGCGAGACTGCGCGAGCAGGCGGGCGGGCGGCTGACGGTGATGCCCGGCGCCGGCGTGCGCCCCGGCAATATCGC
CGGGCTGGCGGCGGCGAGCGGCTGCATCGAGTTCCACGCGTCGGCGCGCGGCCAGGTGGCGAGCGCGATGCGCTACCGGC
GCGGCGGCGTCGGCATGGGCGCGTCCGGCGTCGACGAATATGCGCGGCAGGAAACCTCTGCGTCGCAGGTGAGGGCGTTG
CGGGAGGCGCTGGACAAGGCATAG

Upstream 100 bases:

>100_bases
TCCATGCTCCCAAACCGCCGCGCGCCTTGCGCCGGCGGTTTTCGCGTTTTTGGGGCACCTTGGCCGCTGGGCATGGTCTG
CAGAATGGAGAGGAAGGGAA

Downstream 100 bases:

>100_bases
ACGCGGCCGTTTGCCATCATCTCGGCATGAAATGTTCCGCAGTCTGAATTTACGTTAAATATGTGGCGCACTTTCTTAAT
AAATGGCATAAGCATCATGT

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MDKILEICAGSLASCIAAQEGGAQRVELCDNLGEGGTTPSYGALAMARGRLNIALHAIIRPRGGDFLYSALEFDAMAHDV
EVCRSLGLDGVVLGLLTADGDVDVARTRQLAALAGPMAVTFHRAFDLAREPEQALEDVIAAGCSRLLSSGQAASAPEGAA
LLARLREQAGGRLTVMPGAGVRPGNIAGLAAASGCIEFHASARGQVASAMRYRRGGVGMGASGVDEYARQETSASQVRAL
REALDKA

Sequences:

>Translated_247_residues
MDKILEICAGSLASCIAAQEGGAQRVELCDNLGEGGTTPSYGALAMARGRLNIALHAIIRPRGGDFLYSALEFDAMAHDV
EVCRSLGLDGVVLGLLTADGDVDVARTRQLAALAGPMAVTFHRAFDLAREPEQALEDVIAAGCSRLLSSGQAASAPEGAA
LLARLREQAGGRLTVMPGAGVRPGNIAGLAAASGCIEFHASARGQVASAMRYRRGGVGMGASGVDEYARQETSASQVRAL
REALDKA
>Mature_247_residues
MDKILEICAGSLASCIAAQEGGAQRVELCDNLGEGGTTPSYGALAMARGRLNIALHAIIRPRGGDFLYSALEFDAMAHDV
EVCRSLGLDGVVLGLLTADGDVDVARTRQLAALAGPMAVTFHRAFDLAREPEQALEDVIAAGCSRLLSSGQAASAPEGAA
LLARLREQAGGRLTVMPGAGVRPGNIAGLAAASGCIEFHASARGQVASAMRYRRGGVGMGASGVDEYARQETSASQVRAL
REALDKA

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=238, Percent_Identity=44.9579831932773, Blast_Score=210, Evalue=7e-55,
Organism=Escherichia coli, GI87081995, Length=246, Percent_Identity=43.0894308943089, Blast_Score=185, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17556905, Length=241, Percent_Identity=36.9294605809129, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21355415, Length=234, Percent_Identity=39.7435897435897, Blast_Score=158, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_CHRVO (Q7NY61)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901084.1
- ProteinModelPortal:   Q7NY61
- SMR:   Q7NY61
- GeneID:   2551138
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1414
- NMPDR:   fig|243365.1.peg.1414
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- PhylomeDB:   Q7NY61
- ProtClustDB:   CLSK2521469
- BioCyc:   CVIO243365:CV_1414-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 25406; Mature: 25406

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKILEICAGSLASCIAAQEGGAQRVELCDNLGEGGTTPSYGALAMARGRLNIALHAIIR
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEEEEC
PRGGDFLYSALEFDAMAHDVEVCRSLGLDGVVLGLLTADGDVDVARTRQLAALAGPMAVT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCHHHHH
FHRAFDLAREPEQALEDVIAAGCSRLLSSGQAASAPEGAALLARLREQAGGRLTVMPGAG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCC
VRPGNIAGLAAASGCIEFHASARGQVASAMRYRRGGVGMGASGVDEYARQETSASQVRAL
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHH
REALDKA
HHHHHCC
>Mature Secondary Structure
MDKILEICAGSLASCIAAQEGGAQRVELCDNLGEGGTTPSYGALAMARGRLNIALHAIIR
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEEEEC
PRGGDFLYSALEFDAMAHDVEVCRSLGLDGVVLGLLTADGDVDVARTRQLAALAGPMAVT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCHHHHH
FHRAFDLAREPEQALEDVIAAGCSRLLSSGQAASAPEGAALLARLREQAGGRLTVMPGAG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCC
VRPGNIAGLAAASGCIEFHASARGQVASAMRYRRGGVGMGASGVDEYARQETSASQVRAL
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHH
REALDKA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782