Click here to switch to the map view.

The map label for this gene is gst1 [C]

Identifier: 34496619

GI number: 34496619

Start: 1223862

End: 1224482

Strand: Reverse

Name: gst1 [C]

Synonym: CV_1164

Alternate gene names: 34496619

Gene position: 1224482-1223862 (Counterclockwise)

Preceding gene: 34496622

Following gene: 34496617

Centisome position: 25.77

GC content: 66.18

Gene sequence:

>621_bases
ATGTCGAAAGAGCTCGTCTTCTATACCAACCCGCAGTCGCGGGGCAATATCGTGCACTGGATGCTAGAAGAAGTGGGCGC
GCCCTACCGCCCGGTGCTGCTGGAATACGGCGCGTCGATGAAGGCGCCGGAGTATCTGGCCATCAATCCGATGGGCAAGG
TGCCGGCCATCCGGCACGGCGACCAGGTGGTCACAGAAGGCGCGGCCATCTGCGCCTATCTGGCCGACGCTTTTCCCGAA
GCCGGCCTCGCGCCGGCGCCCGCCGAGCGCGGCGATTATTATCGCTGGCTGTTTTTCGCCGCCAGCTGCGTGGAACACGC
TTGGACCAACCAGGCCGCCGGCTTCACGCCCACCCAGGAGCAGCAGCGCATGTTCGGCTACGGTTCCTACGAGGCGACGA
TGAATGCGCTGGCCAAGGCGGTGGCCGGCCGCCGCTATATCGCCGGAAACCGCTTCAGCGCGGCCGACGTCTATGTCGGC
CGCACGATAGGCTACGGCATCGATTTCGGCAATATGCGCGACTGGCCGGAACTGGTTGCCTACTGGGACGGCCTGAAAGA
CCGGCCGGCCCTGCTGCGCGCCGCCGAGCAGGCGGCCCGGTGGCAGGCCGGCAAGGCTTAA

Upstream 100 bases:

>100_bases
GGCGCGCGCCGTCCATGCATGATGCATGACCAGGCAGTAGCCGGGAGACCGTCCCGCCGCGCGCCTGCGCCGCAGCCACC
ACATAGAAAGGTTGGAGATC

Downstream 100 bases:

>100_bases
GCTCCCTGGCGACGCCGGCAGCGGGGGGCCTTCCGCCCCCCGCGCCAGGCCCCGCTACGCCGGCCGCAGCCGCGCGGTGA
AGTGGCGCAATATCGGCGGC

Product: glutathione S-transferase family protein

Products: HX; R-S-glutathione

Alternate protein names: Glutathione S-Transferase Domain-Containing Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase Protein; Glutathione S-Transferase Domain; Glutathione S-Transferase Family Protein; Glutathione Transferase; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase III; Glutathione S-Transferase N-Terminal Domain; Glutathionine S-Transferase; Glutathione S-Transferase N-Terminal Domain-Containing; Transcriptional Regulator; Glutathione Transferase Protein; Glutathione S Transferase; Glutatione S-Transferase; GSH-Dependent Dehydroascorbate Reductase; Gluthione S-Transferase

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSKELVFYTNPQSRGNIVHWMLEEVGAPYRPVLLEYGASMKAPEYLAINPMGKVPAIRHGDQVVTEGAAICAYLADAFPE
AGLAPAPAERGDYYRWLFFAASCVEHAWTNQAAGFTPTQEQQRMFGYGSYEATMNALAKAVAGRRYIAGNRFSAADVYVG
RTIGYGIDFGNMRDWPELVAYWDGLKDRPALLRAAEQAARWQAGKA

Sequences:

>Translated_206_residues
MSKELVFYTNPQSRGNIVHWMLEEVGAPYRPVLLEYGASMKAPEYLAINPMGKVPAIRHGDQVVTEGAAICAYLADAFPE
AGLAPAPAERGDYYRWLFFAASCVEHAWTNQAAGFTPTQEQQRMFGYGSYEATMNALAKAVAGRRYIAGNRFSAADVYVG
RTIGYGIDFGNMRDWPELVAYWDGLKDRPALLRAAEQAARWQAGKA
>Mature_205_residues
SKELVFYTNPQSRGNIVHWMLEEVGAPYRPVLLEYGASMKAPEYLAINPMGKVPAIRHGDQVVTEGAAICAYLADAFPEA
GLAPAPAERGDYYRWLFFAASCVEHAWTNQAAGFTPTQEQQRMFGYGSYEATMNALAKAVAGRRYIAGNRFSAADVYVGR
TIGYGIDFGNMRDWPELVAYWDGLKDRPALLRAAEQAARWQAGKA

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18

Molecular weight: Translated: 22769; Mature: 22638

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKELVFYTNPQSRGNIVHWMLEEVGAPYRPVLLEYGASMKAPEYLAINPMGKVPAIRHG
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
DQVVTEGAAICAYLADAFPEAGLAPAPAERGDYYRWLFFAASCVEHAWTNQAAGFTPTQE
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHH
QQRMFGYGSYEATMNALAKAVAGRRYIAGNRFSAADVYVGRTIGYGIDFGNMRDWPELVA
HHHHHCCCCHHHHHHHHHHHHHCCEEECCCCCCCHHEEECCCCCCCCCCCCCCCHHHHHH
YWDGLKDRPALLRAAEQAARWQAGKA
HHCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKELVFYTNPQSRGNIVHWMLEEVGAPYRPVLLEYGASMKAPEYLAINPMGKVPAIRHG
CCCEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
DQVVTEGAAICAYLADAFPEAGLAPAPAERGDYYRWLFFAASCVEHAWTNQAAGFTPTQE
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHH
QQRMFGYGSYEATMNALAKAVAGRRYIAGNRFSAADVYVGRTIGYGIDFGNMRDWPELVA
HHHHHCCCCHHHHHHHHHHHHHCCEEECCCCCCCHHEEECCCCCCCCCCCCCCCHHHHHH
YWDGLKDRPALLRAAEQAARWQAGKA
HHCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA