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The map label for this gene is sgrR [H]

Identifier: 34496622

GI number: 34496622

Start: 1225643

End: 1227319

Strand: Reverse

Name: sgrR [H]

Synonym: CV_1167

Alternate gene names: 34496622

Gene position: 1227319-1225643 (Counterclockwise)

Preceding gene: 34496624

Following gene: 34496619

Centisome position: 25.83

GC content: 69.71

Gene sequence:

>1677_bases
ATGCGCCTGCTCCAACACTACCAGCGCCTGAGCCTGGCCTTCCCCGCGCACGACGGCCCGGCGCGGCTGGCAGACATCGC
CGCCGCCCTGCATTGCAGCCCGCGCCATGCCCGCGAACTGCTGCAGAGCATGGCGGCAAACGGCTGGCTGCGATGGCTAC
CCGGCCTGGGGCGCGGCCATCCGTCGCGGCTGCGCCTGCTCGCGCCGACAGGCCAGTTGGAAACGGAAGCGGTGCGCGCC
CACCTGGCCGCTGGCGACATCGAAAAGGCGATGCGCTTGCTGCCCGCAGCCGCCCGCAGCCAAGTGGCCGAGCTGCTGCC
CGCTTATCTCGGCGTGTCGCCGGCCGAACCGCAAACGCTGCGCCTGCCCTTCTACCGGCCGCTGCACAGCCTGGACCCGG
TCCGGATCAATCGCCGCACCGAATGCCACCTGATCCGCCAGATCTTCGACGGCCTGACCCGCTACAACCGCGCCCAGGGG
GAAATCGTCCCGGCGCTGGCCCACCACTGGAGCCATGACGGCGCATGGCGGAACTGGCGCTTCCATCTGCGCCCCGGCGT
CGCCTTCCACCATGGCCGCGCGCTGGATGGCGAAGACGTCCGCCAGAGCCTGCTGCGCTTGCGCGACGAGGCCGGTCCGC
ACCAGGGCCTGCTGCTCCATATGGAAAATGTGAGCCTGCCCGCGCCGCTGACCGTCGACATCCGCCTGGCCCGCCCCGAC
GCCTTGCTGCCGCGGCGGCTGGCCGACAGCGCCGCCACCATCCTGCCGCGCGACCGCTGGCCGCAAGCCGACTTCGGCCG
CTTCCCCATCGGCACCGGCGCGTTCAAGCTGGAAGCCAACAACGACTACCGCGCCACGCTGCGCGCCTTCGACCGCCACT
GGAAAGAAAGGCCGCTCTTGGACGCCGTGGATATCTGGGTGGTGGACGATCCGGATGTGCGGGCCCGGCTGGATGCCCGC
TTCTGCCACCCGGATAAGCCCGCAGTCCGGCCATCACTGCAGCAACTGGAGGCCGGCTGCAGCTATCTGGCCGCGAACCC
GGCCCGGCTGGACGCCGCTCAACGGCGGACGCTGGCCGACTGGCTGCACCCAACCGTCTGGCAAGCCGCGCTTGCCGGCG
AGCCGGCGCTGGGCATGCTGCCGCAATGGCGGCACCGCCCGGCGCCCGTCCAGCCGCAGCCCCCGCGCCTGCCGCCGACG
CTGCGGCTGGTCACCTACCAACTGCCGGCCCATATCGAGCTGGCCGAGGCCGTGGCGCGCCGCTTGCGCGACATTGGCAG
CCGGATCGCGCTGACCGTCATGTCCTATCCCGATTTCGCCCGCTACGACTGGCTAGATGACGCGGACCTGCTGCTGACCG
GCGAAGTGATGGCCGACGATGTGGATTTCGGCGTCTACCAATGGCTGTGCCAGGATGCCGGCTATCGCCATTGGCTGGAA
GAAGGGACTCGACAAAAAATCCGGCTAACGGAAAGAAGACTGGCGATGGAACCGGACGCGGAGCGGCGCTGGCAAGGCTA
CGAAGCGCTGGCGCGAACGCTGGTGGAGGAAGCCAGCCTGATTCCGCTGCGGCATCATGTCCAGACGATGGAATTCGCGC
CGCAGCTGCGGGGCGTCACGCTGGCGCAGTGCGGCTGGATGGATTTCGGCAAAGCGTGGCTGGCTCCCCCGCTCTGA

Upstream 100 bases:

>100_bases
CCGCGGACATGCGCGCTCCATGACATTTGACAGAAGCGGCAGTATCCGGCACAAAAGCGGGAACAAAAACGGAACAGATC
AAAGCCATTCCTCCCCTTTT

Downstream 100 bases:

>100_bases
GCAAGCCCTGGCTCAGATGGCGGCGTCCGAGTGATAACGCAGCCAGAAAGCCTCGCGGCAGCCGTTGTCGAAGCTTTTGC
TCATCGGCTCGATGCCCGGC

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MRLLQHYQRLSLAFPAHDGPARLADIAAALHCSPRHARELLQSMAANGWLRWLPGLGRGHPSRLRLLAPTGQLETEAVRA
HLAAGDIEKAMRLLPAAARSQVAELLPAYLGVSPAEPQTLRLPFYRPLHSLDPVRINRRTECHLIRQIFDGLTRYNRAQG
EIVPALAHHWSHDGAWRNWRFHLRPGVAFHHGRALDGEDVRQSLLRLRDEAGPHQGLLLHMENVSLPAPLTVDIRLARPD
ALLPRRLADSAATILPRDRWPQADFGRFPIGTGAFKLEANNDYRATLRAFDRHWKERPLLDAVDIWVVDDPDVRARLDAR
FCHPDKPAVRPSLQQLEAGCSYLAANPARLDAAQRRTLADWLHPTVWQAALAGEPALGMLPQWRHRPAPVQPQPPRLPPT
LRLVTYQLPAHIELAEAVARRLRDIGSRIALTVMSYPDFARYDWLDDADLLLTGEVMADDVDFGVYQWLCQDAGYRHWLE
EGTRQKIRLTERRLAMEPDAERRWQGYEALARTLVEEASLIPLRHHVQTMEFAPQLRGVTLAQCGWMDFGKAWLAPPL

Sequences:

>Translated_558_residues
MRLLQHYQRLSLAFPAHDGPARLADIAAALHCSPRHARELLQSMAANGWLRWLPGLGRGHPSRLRLLAPTGQLETEAVRA
HLAAGDIEKAMRLLPAAARSQVAELLPAYLGVSPAEPQTLRLPFYRPLHSLDPVRINRRTECHLIRQIFDGLTRYNRAQG
EIVPALAHHWSHDGAWRNWRFHLRPGVAFHHGRALDGEDVRQSLLRLRDEAGPHQGLLLHMENVSLPAPLTVDIRLARPD
ALLPRRLADSAATILPRDRWPQADFGRFPIGTGAFKLEANNDYRATLRAFDRHWKERPLLDAVDIWVVDDPDVRARLDAR
FCHPDKPAVRPSLQQLEAGCSYLAANPARLDAAQRRTLADWLHPTVWQAALAGEPALGMLPQWRHRPAPVQPQPPRLPPT
LRLVTYQLPAHIELAEAVARRLRDIGSRIALTVMSYPDFARYDWLDDADLLLTGEVMADDVDFGVYQWLCQDAGYRHWLE
EGTRQKIRLTERRLAMEPDAERRWQGYEALARTLVEEASLIPLRHHVQTMEFAPQLRGVTLAQCGWMDFGKAWLAPPL
>Mature_558_residues
MRLLQHYQRLSLAFPAHDGPARLADIAAALHCSPRHARELLQSMAANGWLRWLPGLGRGHPSRLRLLAPTGQLETEAVRA
HLAAGDIEKAMRLLPAAARSQVAELLPAYLGVSPAEPQTLRLPFYRPLHSLDPVRINRRTECHLIRQIFDGLTRYNRAQG
EIVPALAHHWSHDGAWRNWRFHLRPGVAFHHGRALDGEDVRQSLLRLRDEAGPHQGLLLHMENVSLPAPLTVDIRLARPD
ALLPRRLADSAATILPRDRWPQADFGRFPIGTGAFKLEANNDYRATLRAFDRHWKERPLLDAVDIWVVDDPDVRARLDAR
FCHPDKPAVRPSLQQLEAGCSYLAANPARLDAAQRRTLADWLHPTVWQAALAGEPALGMLPQWRHRPAPVQPQPPRLPPT
LRLVTYQLPAHIELAEAVARRLRDIGSRIALTVMSYPDFARYDWLDDADLLLTGEVMADDVDFGVYQWLCQDAGYRHWLE
EGTRQKIRLTERRLAMEPDAERRWQGYEALARTLVEEASLIPLRHHVQTMEFAPQLRGVTLAQCGWMDFGKAWLAPPL

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=575, Percent_Identity=31.1304347826087, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1786650, Length=577, Percent_Identity=28.9428076256499, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789966, Length=204, Percent_Identity=28.4313725490196, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63318; Mature: 63318

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLQHYQRLSLAFPAHDGPARLADIAAALHCSPRHARELLQSMAANGWLRWLPGLGRGH
CCHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCCCC
PSRLRLLAPTGQLETEAVRAHLAAGDIEKAMRLLPAAARSQVAELLPAYLGVSPAEPQTL
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
RLPFYRPLHSLDPVRINRRTECHLIRQIFDGLTRYNRAQGEIVPALAHHWSHDGAWRNWR
ECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCE
FHLRPGVAFHHGRALDGEDVRQSLLRLRDEAGPHQGLLLHMENVSLPAPLTVDIRLARPD
EEECCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCC
ALLPRRLADSAATILPRDRWPQADFGRFPIGTGAFKLEANNDYRATLRAFDRHWKERPLL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
DAVDIWVVDDPDVRARLDARFCHPDKPAVRPSLQQLEAGCSYLAANPARLDAAQRRTLAD
CEEEEEEECCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHH
WLHPTVWQAALAGEPALGMLPQWRHRPAPVQPQPPRLPPTLRLVTYQLPAHIELAEAVAR
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
RLRDIGSRIALTVMSYPDFARYDWLDDADLLLTGEVMADDVDFGVYQWLCQDAGYRHWLE
HHHHHCHHEEEEEECCCCCHHCCCCCCCCEEEECCHHHCCCHHHHHHHHHHCCCHHHHHH
EGTRQKIRLTERRLAMEPDAERRWQGYEALARTLVEEASLIPLRHHVQTMEFAPQLRGVT
HCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCE
LAQCGWMDFGKAWLAPPL
EECCCCHHHCCCCCCCCC
>Mature Secondary Structure
MRLLQHYQRLSLAFPAHDGPARLADIAAALHCSPRHARELLQSMAANGWLRWLPGLGRGH
CCHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCCCC
PSRLRLLAPTGQLETEAVRAHLAAGDIEKAMRLLPAAARSQVAELLPAYLGVSPAEPQTL
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
RLPFYRPLHSLDPVRINRRTECHLIRQIFDGLTRYNRAQGEIVPALAHHWSHDGAWRNWR
ECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCE
FHLRPGVAFHHGRALDGEDVRQSLLRLRDEAGPHQGLLLHMENVSLPAPLTVDIRLARPD
EEECCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCC
ALLPRRLADSAATILPRDRWPQADFGRFPIGTGAFKLEANNDYRATLRAFDRHWKERPLL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
DAVDIWVVDDPDVRARLDARFCHPDKPAVRPSLQQLEAGCSYLAANPARLDAAQRRTLAD
CEEEEEEECCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHCCCHHHHHHHHHHHHHH
WLHPTVWQAALAGEPALGMLPQWRHRPAPVQPQPPRLPPTLRLVTYQLPAHIELAEAVAR
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
RLRDIGSRIALTVMSYPDFARYDWLDDADLLLTGEVMADDVDFGVYQWLCQDAGYRHWLE
HHHHHCHHEEEEEECCCCCHHCCCCCCCCEEEECCHHHCCCHHHHHHHHHHCCCHHHHHH
EGTRQKIRLTERRLAMEPDAERRWQGYEALARTLVEEASLIPLRHHVQTMEFAPQLRGVT
HCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCE
LAQCGWMDFGKAWLAPPL
EECCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA