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The map label for this gene is prmA

Identifier: 34496439

GI number: 34496439

Start: 1020782

End: 1021678

Strand: Reverse

Name: prmA

Synonym: CV_0984

Alternate gene names: 34496439

Gene position: 1021678-1020782 (Counterclockwise)

Preceding gene: 34496440

Following gene: 34496438

Centisome position: 21.5

GC content: 66.89

Gene sequence:

>897_bases
ATGGCATGGTTGCAAGCCACCATTGACTCCGACTCCGCTGTCGCCGAGCGTCTGGCCGACGCGCTGATGGACGCCGGCGC
CCTGTCCACCGCGATCGAGGACGCCTGGGCCGGCACCGACAAGGAACAGCCCATCTTCGGCGAGCCCGGCGAGCCGGTGG
ACCAGCTGTGGAGCCAGAGCCGCATCATCACGCTGTTCGACGAGAGCGCCGACGTGGCGCTCTTGATCGCCGCCGCGGCC
AACGCCTGCCAGCTGGCCATGCCGGCCTACAGCGTCGAGCGCGTCGAAGAGCAGGACTGGGTGCGGCTGACGCAATCCCA
GTTCGAGCCGATCCGCATCTCCGACCGGCTGTGGATCACCCCCACCTGGCACGAGGCGCCGGCTCCCAACGCGGTCAACC
TGCAGCTGGACCCGGGCCTCGCCTTCGGCACCGGCAGCCATCCGACTACCCGCCTGTGCCTGCAATGGCTGGACAAGCAG
CTGCAGGGCAATGAAAGCGTGCTCGACTACGGCTGCGGCTCCGGCATCCTGGCCATCGCCGCGCTGAAGCTGGGCGCGGC
CTCCGCCGTCGGCATCGACATCGACCAGCAGGCGGTGCGCGCCAGCCAGGACAATGCCGAGCAGAACGGCGTGAAGGCGG
ATTTCTTCCTGCCCAACGCCAATCCCGCCGCCCAGTACGACGTGGTGCTGGCCAACATCCTGGCCAATCCGCTGCGCATG
TTGGGCGACCTGCTGGCAAGCCATGTGAAAACCGGTGGTAGAATCGTGCTTTCCGGCATCCTCGCCGAACAGGCCGACGA
ACTGTCCGCCATCTACAGCCAATGGTTCGAGATGGACCCGCCGGTGTTCGACGAAGGATGGACTAGACTGACAGGAACCC
GACGCGCCGCCGTATGA

Upstream 100 bases:

>100_bases
CGCTGCACCAGGAGCTGTTCCTGGATGCGGCCTTCCAGCGCGGCGGCACCAGCATCCATTACCTGGAGCACCGGCTGCAG
CAGAAGAAAGGGGAAGCCTG

Downstream 100 bases:

>100_bases
CATACACGACACAGTGCCCCAACTGCCAGACCCGATTCAAGGTCAATGACAGCCAGTTAGCAGCCGCCGATGGACTGGTG
CGCTGCGGGCGCTGTTCGCA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MAWLQATIDSDSAVAERLADALMDAGALSTAIEDAWAGTDKEQPIFGEPGEPVDQLWSQSRIITLFDESADVALLIAAAA
NACQLAMPAYSVERVEEQDWVRLTQSQFEPIRISDRLWITPTWHEAPAPNAVNLQLDPGLAFGTGSHPTTRLCLQWLDKQ
LQGNESVLDYGCGSGILAIAALKLGAASAVGIDIDQQAVRASQDNAEQNGVKADFFLPNANPAAQYDVVLANILANPLRM
LGDLLASHVKTGGRIVLSGILAEQADELSAIYSQWFEMDPPVFDEGWTRLTGTRRAAV

Sequences:

>Translated_298_residues
MAWLQATIDSDSAVAERLADALMDAGALSTAIEDAWAGTDKEQPIFGEPGEPVDQLWSQSRIITLFDESADVALLIAAAA
NACQLAMPAYSVERVEEQDWVRLTQSQFEPIRISDRLWITPTWHEAPAPNAVNLQLDPGLAFGTGSHPTTRLCLQWLDKQ
LQGNESVLDYGCGSGILAIAALKLGAASAVGIDIDQQAVRASQDNAEQNGVKADFFLPNANPAAQYDVVLANILANPLRM
LGDLLASHVKTGGRIVLSGILAEQADELSAIYSQWFEMDPPVFDEGWTRLTGTRRAAV
>Mature_297_residues
AWLQATIDSDSAVAERLADALMDAGALSTAIEDAWAGTDKEQPIFGEPGEPVDQLWSQSRIITLFDESADVALLIAAAAN
ACQLAMPAYSVERVEEQDWVRLTQSQFEPIRISDRLWITPTWHEAPAPNAVNLQLDPGLAFGTGSHPTTRLCLQWLDKQL
QGNESVLDYGCGSGILAIAALKLGAASAVGIDIDQQAVRASQDNAEQNGVKADFFLPNANPAAQYDVVLANILANPLRML
GDLLASHVKTGGRIVLSGILAEQADELSAIYSQWFEMDPPVFDEGWTRLTGTRRAAV

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=299, Percent_Identity=48.1605351170569, Blast_Score=231, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_CHRVO (P60091)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900654.1
- ProteinModelPortal:   P60091
- GeneID:   2550969
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_0984
- NMPDR:   fig|243365.1.peg.984
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- PhylomeDB:   P60091
- ProtClustDB:   PRK00517
- BioCyc:   CVIO243365:CV_0984-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32112; Mature: 31981

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWLQATIDSDSAVAERLADALMDAGALSTAIEDAWAGTDKEQPIFGEPGEPVDQLWSQS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
RIITLFDESADVALLIAAAANACQLAMPAYSVERVEEQDWVRLTQSQFEPIRISDRLWIT
CEEEEECCCCCEEEEEEHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEE
PTWHEAPAPNAVNLQLDPGLAFGTGSHPTTRLCLQWLDKQLQGNESVLDYGCGSGILAIA
ECCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHH
ALKLGAASAVGIDIDQQAVRASQDNAEQNGVKADFFLPNANPAAQYDVVLANILANPLRM
HHHHCCCCEECCCCCHHHHHHCCCCHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LGDLLASHVKTGGRIVLSGILAEQADELSAIYSQWFEMDPPVFDEGWTRLTGTRRAAV
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
AWLQATIDSDSAVAERLADALMDAGALSTAIEDAWAGTDKEQPIFGEPGEPVDQLWSQS
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCC
RIITLFDESADVALLIAAAANACQLAMPAYSVERVEEQDWVRLTQSQFEPIRISDRLWIT
CEEEEECCCCCEEEEEEHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEE
PTWHEAPAPNAVNLQLDPGLAFGTGSHPTTRLCLQWLDKQLQGNESVLDYGCGSGILAIA
ECCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHH
ALKLGAASAVGIDIDQQAVRASQDNAEQNGVKADFFLPNANPAAQYDVVLANILANPLRM
HHHHCCCCEECCCCCHHHHHHCCCCHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LGDLLASHVKTGGRIVLSGILAEQADELSAIYSQWFEMDPPVFDEGWTRLTGTRRAAV
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782