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The map label for this gene is trpE(G) [H]

Identifier: 34496023

GI number: 34496023

Start: 608048

End: 609376

Strand: Reverse

Name: trpE(G) [H]

Synonym: CV_0568

Alternate gene names: 34496023

Gene position: 609376-608048 (Counterclockwise)

Preceding gene: 34496024

Following gene: 34496022

Centisome position: 12.83

GC content: 69.98

Gene sequence:

>1329_bases
ATGAATAAGATCCGACTGCACTCCGTCCCCGCGCCGGCCGATGGCCGCCAAACGCCGCTGTTCGCGCTGCGCTGCAATTA
CGATTACAGCGGCAAGTACGCGCTGCATGAGCGCGCAGTCGAACGCGCCGCGCTCAGCGCGCTGTTCTTCGCCGACCGCA
TCGCGCTGCTGCCGCGCAGCCGCAACGGCGTCCGCATCGCCGAGACGCTGGCGCCGCTGCTGGGCCTGAGCCCCGACCCC
GCCGCGCCCGGCGCGTTCCGGCTCCCGCTGGATCCCGACGCGCCGCTGGCCGAGCGGCTGCAACAGCTGCTGGATTTGCC
GGCCCGCTTCGACGCGGACCCGCGCTTCGGCCTGTACGGCTTCTTCTGCTATGAACTGCTCCACGCCAAGCTGGGACTCA
ACGCCGGCCTGCTGGGCGTATTCCATGTGCCCGAGCGGCTGATCGTCGATGGCGAAGCCGTAGACTGCCTGCTGGACCCG
GCCGACGCGGGCGGCGAAAGCTGGCCGCTGGCGCTGGGTCCGATGCTGGGCGCCGACGACTTCGCCGCCGGCCGCGGCCT
GCCCTACGAGCGGATGTACGCCATCGCCTCCCGGCGCATCGCGGACGGCGCGCTGCGTTCGGTCAACCCCAGCTTCGCGA
TCCAACGCCCCTGCGCGCGCGACGCCTACCGGATCCACCAGGATCTGCTGGCGCGCAATCCCGCCCCCTACAACCTGTAC
TTCGACGGCGGCGACTTCCAGCTGGCCGGCTCCTCGCCGGCGATGTTCCTGCGCCTGCGCGGCGGCCGGCTTGCCACCAG
TCCGATCTGCGGCACCATCGCGCGCGGCCGCGGCGAGGCGGAAGACGAAGCGCAGGTGGCAACATTGCTGGCGTCCGACA
AGGACAGATTCGAACTGGAGGAATGCGTGCGCGCCGACATGCAGGCCAAGGAGGCCAGCTGCGAGGACATCCGCGTCGAC
ATCGAACGGGAGGTAGAGCGCTTCGCCAACGTGTTCCACACCTCGGCCAGCGTCAGCGCGAGGCTGAAGCCCGGAAAGAC
CCTGGCCGACGCGATCTGCGACCACTTGTGGCCCGCCACTGTCGTCGGCACGCCCGTCGACGCCGCCGCACGGCTGCTCG
CCGAACACGAAAGCCGCCGCTGGTACGCCGGAGCCTTCGGCTACCTGTGCGCCAACGAGGTGGAGCTGGGCACCATGATC
CGCACCGCGCTGCTGGCGGACGGCATGGCGACCACCCGGGTGGGCAGCACGCTGAGCGCGCGCTCCAGCCCGCAGTTGGA
GCAGAGCGAACTGGAAGCCAAGGCTTCGCTGATCCTGGGTGTATTGTGA

Upstream 100 bases:

>100_bases
TCTCGCAATACATCGTGCTGCTGCTGTACCGCTACCAGGCCTGGAGCGAGGGCGCGCCCGGCGGCCGCAAGGTCAAATTC
TCCTCACGCTATCTGCAAGT

Downstream 100 bases:

>100_bases
GCGCCCTCACCATCGAAGACATCGACGCCGACGCGATCACGATACGGCTGGTCAACACCGCCAAGACTTATCTCGTCCCG
CTGGACCGGGTAATCCGCTT

Product: anthranilate synthase

Products: NA

Alternate protein names: Glutamine amidotransferase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNKIRLHSVPAPADGRQTPLFALRCNYDYSGKYALHERAVERAALSALFFADRIALLPRSRNGVRIAETLAPLLGLSPDP
AAPGAFRLPLDPDAPLAERLQQLLDLPARFDADPRFGLYGFFCYELLHAKLGLNAGLLGVFHVPERLIVDGEAVDCLLDP
ADAGGESWPLALGPMLGADDFAAGRGLPYERMYAIASRRIADGALRSVNPSFAIQRPCARDAYRIHQDLLARNPAPYNLY
FDGGDFQLAGSSPAMFLRLRGGRLATSPICGTIARGRGEAEDEAQVATLLASDKDRFELEECVRADMQAKEASCEDIRVD
IEREVERFANVFHTSASVSARLKPGKTLADAICDHLWPATVVGTPVDAAARLLAEHESRRWYAGAFGYLCANEVELGTMI
RTALLADGMATTRVGSTLSARSSPQLEQSELEAKASLILGVL

Sequences:

>Translated_442_residues
MNKIRLHSVPAPADGRQTPLFALRCNYDYSGKYALHERAVERAALSALFFADRIALLPRSRNGVRIAETLAPLLGLSPDP
AAPGAFRLPLDPDAPLAERLQQLLDLPARFDADPRFGLYGFFCYELLHAKLGLNAGLLGVFHVPERLIVDGEAVDCLLDP
ADAGGESWPLALGPMLGADDFAAGRGLPYERMYAIASRRIADGALRSVNPSFAIQRPCARDAYRIHQDLLARNPAPYNLY
FDGGDFQLAGSSPAMFLRLRGGRLATSPICGTIARGRGEAEDEAQVATLLASDKDRFELEECVRADMQAKEASCEDIRVD
IEREVERFANVFHTSASVSARLKPGKTLADAICDHLWPATVVGTPVDAAARLLAEHESRRWYAGAFGYLCANEVELGTMI
RTALLADGMATTRVGSTLSARSSPQLEQSELEAKASLILGVL
>Mature_442_residues
MNKIRLHSVPAPADGRQTPLFALRCNYDYSGKYALHERAVERAALSALFFADRIALLPRSRNGVRIAETLAPLLGLSPDP
AAPGAFRLPLDPDAPLAERLQQLLDLPARFDADPRFGLYGFFCYELLHAKLGLNAGLLGVFHVPERLIVDGEAVDCLLDP
ADAGGESWPLALGPMLGADDFAAGRGLPYERMYAIASRRIADGALRSVNPSFAIQRPCARDAYRIHQDLLARNPAPYNLY
FDGGDFQLAGSSPAMFLRLRGGRLATSPICGTIARGRGEAEDEAQVATLLASDKDRFELEECVRADMQAKEASCEDIRVD
IEREVERFANVFHTSASVSARLKPGKTLADAICDHLWPATVVGTPVDAAARLLAEHESRRWYAGAFGYLCANEVELGTMI
RTALLADGMATTRVGSTLSARSSPQLEQSELEAKASLILGVL

Specific function: Menaquinone biosynthesis. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082077, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787518, Length=271, Percent_Identity=30.2583025830258, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786809, Length=264, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=237, Percent_Identity=32.0675105485232, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR010112
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 47931; Mature: 47931

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIRLHSVPAPADGRQTPLFALRCNYDYSGKYALHERAVERAALSALFFADRIALLPRS
CCCEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RNGVRIAETLAPLLGLSPDPAAPGAFRLPLDPDAPLAERLQQLLDLPARFDADPRFGLYG
CCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FFCYELLHAKLGLNAGLLGVFHVPERLIVDGEAVDCLLDPADAGGESWPLALGPMLGADD
HHHHHHHHHHHCCCCCEEEEEECCHHEEECCCCEEEEECCCCCCCCCCCEEECCCCCCCC
FAAGRGLPYERMYAIASRRIADGALRSVNPSFAIQRPCARDAYRIHQDLLARNPAPYNLY
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEEE
FDGGDFQLAGSSPAMFLRLRGGRLATSPICGTIARGRGEAEDEAQVATLLASDKDRFELE
EECCCEEECCCCCEEEEEECCCCEECCCHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
ECVRADMQAKEASCEDIRVDIEREVERFANVFHTSASVSARLKPGKTLADAICDHLWPAT
HHHHHHHHHHHCCCHHHEECHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCHH
VVGTPVDAAARLLAEHESRRWYAGAFGYLCANEVELGTMIRTALLADGMATTRVGSTLSA
HCCCCHHHHHHHHHHHHCCCEECCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCC
RSSPQLEQSELEAKASLILGVL
CCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKIRLHSVPAPADGRQTPLFALRCNYDYSGKYALHERAVERAALSALFFADRIALLPRS
CCCEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RNGVRIAETLAPLLGLSPDPAAPGAFRLPLDPDAPLAERLQQLLDLPARFDADPRFGLYG
CCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
FFCYELLHAKLGLNAGLLGVFHVPERLIVDGEAVDCLLDPADAGGESWPLALGPMLGADD
HHHHHHHHHHHCCCCCEEEEEECCHHEEECCCCEEEEECCCCCCCCCCCEEECCCCCCCC
FAAGRGLPYERMYAIASRRIADGALRSVNPSFAIQRPCARDAYRIHQDLLARNPAPYNLY
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEEE
FDGGDFQLAGSSPAMFLRLRGGRLATSPICGTIARGRGEAEDEAQVATLLASDKDRFELE
EECCCEEECCCCCEEEEEECCCCEECCCHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHH
ECVRADMQAKEASCEDIRVDIEREVERFANVFHTSASVSARLKPGKTLADAICDHLWPAT
HHHHHHHHHHHCCCHHHEECHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCHH
VVGTPVDAAARLLAEHESRRWYAGAFGYLCANEVELGTMIRTALLADGMATTRVGSTLSA
HCCCCHHHHHHHHHHHHCCCEECCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCC
RSSPQLEQSELEAKASLILGVL
CCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8939798 [H]