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The map label for this gene is ppk

Identifier: 33864509

GI number: 33864509

Start: 2372062

End: 2374200

Strand: Direct

Name: ppk

Synonym: PMT2245

Alternate gene names: 33864509

Gene position: 2372062-2374200 (Clockwise)

Preceding gene: 33864508

Following gene: 33864510

Centisome position: 98.39

GC content: 50.96

Gene sequence:

>2139_bases
ATGAGTAATCCAGCAGTAGCTTCGGAGCACTACATCAACCGAGAGCTCAGCTGGATCTCCTTCAACGAAAGGGTCCTTGC
TCAGGCACTGGATACGCGCACCCCGCTGCTGGAACAAGCCAAGTTCAGTGCCATCTTCAGCAACAACCTCGACGAATTCT
TCATGGTTCGCGTGGCCTCCCTCAAAGCACAAGTGGAAGCCGGCATTACCAAAACCAGCGCAGACGGTCTAACCCCTCTT
CAGCAGCTCCTCACGATCCGAGATCACCTTGTTCCTCTCATCGAGCAACAACAAGATCACTACCGTAAACACCTCAAAAA
CCAGCTAGTCGAGCATGGTGTTCACCTACTCGACTATGAGCAACTCAATCCAAAAGAACGCCTCTGGATTGACAATTATT
TCCAAACAGCCATTTTCCCGGTGCTGACACCACTAGCCGTGGATCAAGCCCATCCCTTCCCTTTCGTTAGCAATCTCAGC
CTCAACATTGCGACCCTGATCCTCGATCCGGAAACAGGCCAACAACAATTCGCCCGGGTCAAGATTCCACAAAAAACGAT
CCCTCGGTTTGTAGAGATACCTCCTGATCTAAGTGGCATCAATCCCAAACCAGTTCACACAGCAGTTCCATTGGAGCAAG
TGGTGGCCTTCAACCTCAAATTGCTCTTCCCCGGGATGAAGATTGAAGAGCACTACTTCTTCCGAGTCACCCGCGATGCC
GACCTTGAACTCAGGGACCTAGAAGCCGACGATCTCATGAGCGCCATGGAACAAGGCCTGCATAAGCGGCGGATGGGCGG
AGAAGTGGTGAGACTCGAAGTGACAAACGAAATGCCCCAGAGAGTCGTTGAGATGCTGATTGAAGGTATGGCTGTTGAAG
AAAAAGACCTTTATCGCATCGAGGGACTACTAGGCCTCGATGATCTATTCGGTCTCATGCGTTTACCTCTGGAACAACTC
AAAGACCAACCCCACATTGGCCTGACCGCCAAAGTTCTCTCCCGCAGCCAGCGCAGAATGCTTGAAGACGAATCAATCAA
AGAAGAAGAATTCAAAAGCATCTTCTCGGTGATTCGCCGCAAAGACATTCTCCTTCACCACCCATACGAACTGTTCGCGA
CCTCTGTAGAGGAATTCATCAATCAGGCAGCAGACGATCCCCTAGTCATGGGAATCAAGATCACGCTCTATCGGACATCT
AAGGATTCCCCAATCATTGCGGCCCTGATTCGTGCAGCCGAACACGGAAAGCAGGTCATGGCTCTGGTTGAACTCAAGGC
ACGCTTCGATGAAGGCAACAATATTCAATGGGCCCGTCATCTAGAACGATCTGGCGTTCACGTTGTCTATGGCGTTTTAG
GACTAAAAACCCACACAAAAACCATCTTGGTCGTTCGCAAAGAAAAAGAGCGCCTACGCAGCTACGTGCACATCGGCACA
GGGAACTACAACTCGAAGACATCACGTCTCTATACCGATCTTGGTCTGCTCTCTGCAAGACCGGAACTCAGCCAAGATCT
AGTCGAGCTATTCAATTATCTCACTGGCTTTTCAAAGCAACAAAGCTTCCGTCGACTGCTGGTGGCACCTGTCACCCTAC
GCAAGGGAATGGAATCACTCATCCTCCGCGAAATCGAACACGCCCGCGAAGGTAGAGGCGGACACATCCGCGCCAAGATG
AATGCTCTGGTGGATCCAGCCATCATTAGCCTGCTCTACGAAGCTTCCCAAGTTGGAGTTCGTATCGAACTGATCATCCG
CGGTATGTGCTGTCTCTACCCAGGACGAAAAGGATTCAGCGAAAACATCAGCGTGATCAGCATCATCGGCCGGTTCCTGG
AACACTCCCGTATCTTCTGGTTTGCCAATGACAACAACCCAGAGGTTTATATCGGCAGCGCAGACTTGATGCCTCGAAAC
CTAGACAGACGCGTGGAAGCCATTACTCCAATTGAAGAACCAGAGCAAAAGGAACACCTAGAGCGACTGCTGAACCTCTA
CCTAAACGACAACCGCGAAGCATGGGATATGCAGAGCGATGGCAGCTTTTTACAGCGCCAACCCAATCCCAATAGTGAAG
AACATCGTGCACAGCAACAGCTGATCAACCTTTGGCAACAAGGCATCCCAGCAGCGTGA

Upstream 100 bases:

>100_bases
CCTTGTTGCAGGAGGCCCACCTGCAAGCACAAGTAACACAACAATCAAACAATCATGATTGCTACTTTGCCTGGATAGTG
GATCAACAAACTGGCATTCA

Downstream 100 bases:

>100_bases
AACTCGATGCCTCACGAGACCATAACTGTGAGAAAGTACTCTTTGCTACCTAAAAAGGAATAATCAGCATGCAAAACAGT
TTTTTTACTTAGAAGCGACC

Product: polyphosphate kinase

Products: NA

Alternate protein names: ATP-polyphosphate phosphotransferase; Polyphosphoric acid kinase

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSNPAVASEHYINRELSWISFNERVLAQALDTRTPLLEQAKFSAIFSNNLDEFFMVRVASLKAQVEAGITKTSADGLTPL
QQLLTIRDHLVPLIEQQQDHYRKHLKNQLVEHGVHLLDYEQLNPKERLWIDNYFQTAIFPVLTPLAVDQAHPFPFVSNLS
LNIATLILDPETGQQQFARVKIPQKTIPRFVEIPPDLSGINPKPVHTAVPLEQVVAFNLKLLFPGMKIEEHYFFRVTRDA
DLELRDLEADDLMSAMEQGLHKRRMGGEVVRLEVTNEMPQRVVEMLIEGMAVEEKDLYRIEGLLGLDDLFGLMRLPLEQL
KDQPHIGLTAKVLSRSQRRMLEDESIKEEEFKSIFSVIRRKDILLHHPYELFATSVEEFINQAADDPLVMGIKITLYRTS
KDSPIIAALIRAAEHGKQVMALVELKARFDEGNNIQWARHLERSGVHVVYGVLGLKTHTKTILVVRKEKERLRSYVHIGT
GNYNSKTSRLYTDLGLLSARPELSQDLVELFNYLTGFSKQQSFRRLLVAPVTLRKGMESLILREIEHAREGRGGHIRAKM
NALVDPAIISLLYEASQVGVRIELIIRGMCCLYPGRKGFSENISVISIIGRFLEHSRIFWFANDNNPEVYIGSADLMPRN
LDRRVEAITPIEEPEQKEHLERLLNLYLNDNREAWDMQSDGSFLQRQPNPNSEEHRAQQQLINLWQQGIPAA

Sequences:

>Translated_712_residues
MSNPAVASEHYINRELSWISFNERVLAQALDTRTPLLEQAKFSAIFSNNLDEFFMVRVASLKAQVEAGITKTSADGLTPL
QQLLTIRDHLVPLIEQQQDHYRKHLKNQLVEHGVHLLDYEQLNPKERLWIDNYFQTAIFPVLTPLAVDQAHPFPFVSNLS
LNIATLILDPETGQQQFARVKIPQKTIPRFVEIPPDLSGINPKPVHTAVPLEQVVAFNLKLLFPGMKIEEHYFFRVTRDA
DLELRDLEADDLMSAMEQGLHKRRMGGEVVRLEVTNEMPQRVVEMLIEGMAVEEKDLYRIEGLLGLDDLFGLMRLPLEQL
KDQPHIGLTAKVLSRSQRRMLEDESIKEEEFKSIFSVIRRKDILLHHPYELFATSVEEFINQAADDPLVMGIKITLYRTS
KDSPIIAALIRAAEHGKQVMALVELKARFDEGNNIQWARHLERSGVHVVYGVLGLKTHTKTILVVRKEKERLRSYVHIGT
GNYNSKTSRLYTDLGLLSARPELSQDLVELFNYLTGFSKQQSFRRLLVAPVTLRKGMESLILREIEHAREGRGGHIRAKM
NALVDPAIISLLYEASQVGVRIELIIRGMCCLYPGRKGFSENISVISIIGRFLEHSRIFWFANDNNPEVYIGSADLMPRN
LDRRVEAITPIEEPEQKEHLERLLNLYLNDNREAWDMQSDGSFLQRQPNPNSEEHRAQQQLINLWQQGIPAA
>Mature_711_residues
SNPAVASEHYINRELSWISFNERVLAQALDTRTPLLEQAKFSAIFSNNLDEFFMVRVASLKAQVEAGITKTSADGLTPLQ
QLLTIRDHLVPLIEQQQDHYRKHLKNQLVEHGVHLLDYEQLNPKERLWIDNYFQTAIFPVLTPLAVDQAHPFPFVSNLSL
NIATLILDPETGQQQFARVKIPQKTIPRFVEIPPDLSGINPKPVHTAVPLEQVVAFNLKLLFPGMKIEEHYFFRVTRDAD
LELRDLEADDLMSAMEQGLHKRRMGGEVVRLEVTNEMPQRVVEMLIEGMAVEEKDLYRIEGLLGLDDLFGLMRLPLEQLK
DQPHIGLTAKVLSRSQRRMLEDESIKEEEFKSIFSVIRRKDILLHHPYELFATSVEEFINQAADDPLVMGIKITLYRTSK
DSPIIAALIRAAEHGKQVMALVELKARFDEGNNIQWARHLERSGVHVVYGVLGLKTHTKTILVVRKEKERLRSYVHIGTG
NYNSKTSRLYTDLGLLSARPELSQDLVELFNYLTGFSKQQSFRRLLVAPVTLRKGMESLILREIEHAREGRGGHIRAKMN
ALVDPAIISLLYEASQVGVRIELIIRGMCCLYPGRKGFSENISVISIIGRFLEHSRIFWFANDNNPEVYIGSADLMPRNL
DRRVEAITPIEEPEQKEHLERLLNLYLNDNREAWDMQSDGSFLQRQPNPNSEEHRAQQQLINLWQQGIPAA

Specific function: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)

COG id: COG0855

COG function: function code P; Polyphosphate kinase

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyphosphate kinase family

Homologues:

Organism=Escherichia coli, GI1788847, Length=701, Percent_Identity=35.09272467903, Blast_Score=391, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPK_PROMM (Q7V3U5)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_896069.1
- HSSP:   P0A7B1
- ProteinModelPortal:   Q7V3U5
- SMR:   Q7V3U5
- STRING:   Q7V3U5
- GeneID:   1728396
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT2245
- NMPDR:   fig|74547.1.peg.2236
- eggNOG:   COG0855
- HOGENOM:   HBG341268
- OMA:   NYHAGNA
- ProtClustDB:   PRK05443
- BioCyc:   PMAR74547:PMT2245-MONOMER
- HAMAP:   MF_00347
- InterPro:   IPR003414
- PIRSF:   PIRSF015589
- TIGRFAMs:   TIGR03705

Pfam domain/function: PF02503 PP_kinase

EC number: =2.7.4.1

Molecular weight: Translated: 81570; Mature: 81439

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: ACT_SITE 458-458 ACT_SITE 477-477

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPAVASEHYINRELSWISFNERVLAQALDTRTPLLEQAKFSAIFSNNLDEFFMVRVAS
CCCCCCCHHHHHCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LKAQVEAGITKTSADGLTPLQQLLTIRDHLVPLIEQQQDHYRKHLKNQLVEHGVHLLDYE
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
QLNPKERLWIDNYFQTAIFPVLTPLAVDQAHPFPFVSNLSLNIATLILDPETGQQQFARV
HCCCHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHEE
KIPQKTIPRFVEIPPDLSGINPKPVHTAVPLEQVVAFNLKLLFPGMKIEEHYFFRVTRDA
CCCHHHCCHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCEECCEEEEEEECCC
DLELRDLEADDLMSAMEQGLHKRRMGGEVVRLEVTNEMPQRVVEMLIEGMAVEEKDLYRI
CCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHHHH
EGLLGLDDLFGLMRLPLEQLKDQPHIGLTAKVLSRSQRRMLEDESIKEEEFKSIFSVIRR
HHHCCHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KDILLHHPYELFATSVEEFINQAADDPLVMGIKITLYRTSKDSPIIAALIRAAEHGKQVM
CCHHEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
ALVELKARFDEGNNIQWARHLERSGVHVVYGVLGLKTHTKTILVVRKEKERLRSYVHIGT
HHHHHHHHCCCCCCCHHHHHHHHCCCEEEEHHHHCCCCCEEEEEEECHHHHHHHEEEECC
GNYNSKTSRLYTDLGLLSARPELSQDLVELFNYLTGFSKQQSFRRLLVAPVTLRKGMESL
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ILREIEHAREGRGGHIRAKMNALVDPAIISLLYEASQVGVRIELIIRGMCCLYPGRKGFS
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCC
ENISVISIIGRFLEHSRIFWFANDNNPEVYIGSADLMPRNLDRRVEAITPIEEPEQKEHL
CCHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHH
ERLLNLYLNDNREAWDMQSDGSFLQRQPNPNSEEHRAQQQLINLWQQGIPAA
HHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNPAVASEHYINRELSWISFNERVLAQALDTRTPLLEQAKFSAIFSNNLDEFFMVRVAS
CCCCCCHHHHHCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LKAQVEAGITKTSADGLTPLQQLLTIRDHLVPLIEQQQDHYRKHLKNQLVEHGVHLLDYE
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
QLNPKERLWIDNYFQTAIFPVLTPLAVDQAHPFPFVSNLSLNIATLILDPETGQQQFARV
HCCCHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHEE
KIPQKTIPRFVEIPPDLSGINPKPVHTAVPLEQVVAFNLKLLFPGMKIEEHYFFRVTRDA
CCCHHHCCHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCEECCEEEEEEECCC
DLELRDLEADDLMSAMEQGLHKRRMGGEVVRLEVTNEMPQRVVEMLIEGMAVEEKDLYRI
CCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHHHH
EGLLGLDDLFGLMRLPLEQLKDQPHIGLTAKVLSRSQRRMLEDESIKEEEFKSIFSVIRR
HHHCCHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KDILLHHPYELFATSVEEFINQAADDPLVMGIKITLYRTSKDSPIIAALIRAAEHGKQVM
CCHHEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
ALVELKARFDEGNNIQWARHLERSGVHVVYGVLGLKTHTKTILVVRKEKERLRSYVHIGT
HHHHHHHHCCCCCCCHHHHHHHHCCCEEEEHHHHCCCCCEEEEEEECHHHHHHHEEEECC
GNYNSKTSRLYTDLGLLSARPELSQDLVELFNYLTGFSKQQSFRRLLVAPVTLRKGMESL
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ILREIEHAREGRGGHIRAKMNALVDPAIISLLYEASQVGVRIELIIRGMCCLYPGRKGFS
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCC
ENISVISIIGRFLEHSRIFWFANDNNPEVYIGSADLMPRNLDRRVEAITPIEEPEQKEHL
CCHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHH
ERLLNLYLNDNREAWDMQSDGSFLQRQPNPNSEEHRAQQQLINLWQQGIPAA
HHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12917642