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The map label for this gene is pdxH [H]

Identifier: 33864463

GI number: 33864463

Start: 2324586

End: 2325254

Strand: Direct

Name: pdxH [H]

Synonym: PMT2199

Alternate gene names: 33864463

Gene position: 2324586-2325254 (Clockwise)

Preceding gene: 33864462

Following gene: 33864464

Centisome position: 96.42

GC content: 55.75

Gene sequence:

>669_bases
ATGGGTGCACCCTCCCCTGATCAAGACATAGCAGCGATTAGGCGGAATTACCAAAGAGCAAGCCTGCGCAGTGTCGACCT
AGAGGCCGATCCAGTGGAGCAATTCCGTCGCTGGCTTCAGCAAGCCATCGCAGCTGATCTGCAAGAGTCCACAGCCATGG
TGCTCAGCACCTTTGATGGCAAGCGCCCCAGTAGCCGCACAGTGCTGCTCAAAGCCTTTGACAAGCGCGGATTTGTGTTC
TTCACCAATTACGGCAGCCGAAAAGCCGAAGACATTTCTGCGCATCCGAATGTGAGCCTGCTATTTCCCTGGTATGACCT
TGAGCGGCAAGTCGCAATCATGGGCCCTGCTGAGCGCATCAGCAGAGCTGAATCTCAGGCCTATTTCAGCTCAAGACCCT
TCGGGAGTCGCCTTGGGGTCTGGGTATCGCAGCAAAGCCAAGTAATCAGCTCGCGCCAGATCCTGGAAATGAAATGGCAA
GAAATGAATCGTCGCTTCGCCAATGGTGAAGTACCCCTCCCTGAGTTCTGGGGTGGCTTTCGGGTGGCTCCGACTGAATT
CGAATTCTGGCAGGGACGCGAGAACCGGCTAAACGATCGATTTCGCTACCGACCCCAACAAGACAGCAACCATGCGCAAA
CCTGGCGCATCGAGCGCTTGGCCCCATGA

Upstream 100 bases:

>100_bases
GATTAAGCCTCAGCAGTAAGACACCCTGCTAAACAGATAGAACATCAAGCAGCGGGCCCAAGCGGCATTGGCTAAGAATC
CTCTTAACCCCATCGCTCCC

Downstream 100 bases:

>100_bases
ATTAATTGGTCAAGATGAGCTTGAGCCGCAATGGCTTGCTGTCAGCTTGGATGAGTTGGATGTCCGTCGTGTCTGATCGG
TATGGAGTCCACCACCCCCA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MGAPSPDQDIAAIRRNYQRASLRSVDLEADPVEQFRRWLQQAIAADLQESTAMVLSTFDGKRPSSRTVLLKAFDKRGFVF
FTNYGSRKAEDISAHPNVSLLFPWYDLERQVAIMGPAERISRAESQAYFSSRPFGSRLGVWVSQQSQVISSRQILEMKWQ
EMNRRFANGEVPLPEFWGGFRVAPTEFEFWQGRENRLNDRFRYRPQQDSNHAQTWRIERLAP

Sequences:

>Translated_222_residues
MGAPSPDQDIAAIRRNYQRASLRSVDLEADPVEQFRRWLQQAIAADLQESTAMVLSTFDGKRPSSRTVLLKAFDKRGFVF
FTNYGSRKAEDISAHPNVSLLFPWYDLERQVAIMGPAERISRAESQAYFSSRPFGSRLGVWVSQQSQVISSRQILEMKWQ
EMNRRFANGEVPLPEFWGGFRVAPTEFEFWQGRENRLNDRFRYRPQQDSNHAQTWRIERLAP
>Mature_221_residues
GAPSPDQDIAAIRRNYQRASLRSVDLEADPVEQFRRWLQQAIAADLQESTAMVLSTFDGKRPSSRTVLLKAFDKRGFVFF
TNYGSRKAEDISAHPNVSLLFPWYDLERQVAIMGPAERISRAESQAYFSSRPFGSRLGVWVSQQSQVISSRQILEMKWQE
MNRRFANGEVPLPEFWGGFRVAPTEFEFWQGRENRLNDRFRYRPQQDSNHAQTWRIERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=230, Percent_Identity=41.7391304347826, Blast_Score=168, Evalue=3e-42,
Organism=Escherichia coli, GI1787926, Length=216, Percent_Identity=54.1666666666667, Blast_Score=234, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17553712, Length=230, Percent_Identity=38.695652173913, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319509, Length=211, Percent_Identity=40.7582938388626, Blast_Score=171, Evalue=9e-44,
Organism=Drosophila melanogaster, GI45551845, Length=206, Percent_Identity=43.6893203883495, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24644901, Length=206, Percent_Identity=43.6893203883495, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24644903, Length=175, Percent_Identity=27.4285714285714, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 25836; Mature: 25705

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAPSPDQDIAAIRRNYQRASLRSVDLEADPVEQFRRWLQQAIAADLQESTAMVLSTFDG
CCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
KRPSSRTVLLKAFDKRGFVFFTNYGSRKAEDISAHPNVSLLFPWYDLERQVAIMGPAERI
CCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHH
SRAESQAYFSSRPFGSRLGVWVSQQSQVISSRQILEMKWQEMNRRFANGEVPLPEFWGGF
HHHHHHHHHCCCCCCCHHCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCE
RVAPTEFEFWQGRENRLNDRFRYRPQQDSNHAQTWRIERLAP
EECCCCHHHHCCCHHHCCHHHCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
GAPSPDQDIAAIRRNYQRASLRSVDLEADPVEQFRRWLQQAIAADLQESTAMVLSTFDG
CCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
KRPSSRTVLLKAFDKRGFVFFTNYGSRKAEDISAHPNVSLLFPWYDLERQVAIMGPAERI
CCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHH
SRAESQAYFSSRPFGSRLGVWVSQQSQVISSRQILEMKWQEMNRRFANGEVPLPEFWGGF
HHHHHHHHHCCCCCCCHHCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCE
RVAPTEFEFWQGRENRLNDRFRYRPQQDSNHAQTWRIERLAP
EECCCCHHHHCCCHHHCCHHHCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA