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The map label for this gene is rnhB

Identifier: 33864055

GI number: 33864055

Start: 1886298

End: 1886954

Strand: Reverse

Name: rnhB

Synonym: PMT1788

Alternate gene names: 33864055

Gene position: 1886954-1886298 (Counterclockwise)

Preceding gene: 33864056

Following gene: 33864053

Centisome position: 78.27

GC content: 58.6

Gene sequence:

>657_bases
GTGAACCCGAGGATCCGCGCCGCCGCCGCCGTCGCTCCTCAGCTGCAGGCTGATATGGACCCTTCGGCGGAATCCATCGC
CGGAGTTGATGAGGTGGGTCGGGGCTGCTGGTTTGGTCCTGTGTTTGCAGGAGCGGTTGTCCTCACTGAAGTTGCGGCAG
TCGAATTGTTAGCTGAGGGGTTAACAGATAGCAAAGCACTGACTGTTCGCCGCAGGGCTCGCTTAGTGCCGCTGATTGAG
GATGCCGCGACGGCTTGGGCTCTTGGACAGGCCTCGGCTCGCGAAATTGATGCTCTAGGCATTCGCTCAGCGACGGAACT
TGCCATGCTGAGGGCATTGCAGCGGCTACCTACACCGTTGGAGCTTGTCTTGGTTGATGGCGTGTTGCCATTGCGCCTCT
GGATGGGGCCACAACGTACCGTGGTGCGCGGTGATAGCAAATGTGCGGCCATCGCTGCAGCCAGTGTGTTGGCCAAGCAG
GCTCGTGATGGGCTGATCAAGCGGTTGGCTAGTCGCTTCTATGGCTACGGTTTGGAGCGACATGTTGGCTATGGAACGGC
GATCCACCGGCGTGCCTTGTTGGATTTAGGCCCTACAGAGCTTCATCGTCGCTCATTCCTCACCAAGCTGTTTGCTGTTA
ATGGCAGTCTCACTTGA

Upstream 100 bases:

>100_bases
AATGAGCCTCTAAGTGTTCAAATCACTCCTCTTGAGGTTGATCATTCATCGAGTAGCGCTTCTGTAGAAACCGTTTCTTC
AATTTCCGAGCCGCAGGAAA

Downstream 100 bases:

>100_bases
GCGTATGGGTGTCTCTTGGCACCATTGGCTGAAATCCTTGACAAGTTGTTGGCCAACACGGGTTTTGATGCCAAGCAGGA
TGCCGCTGAGAATTGATTGA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MNPRIRAAAAVAPQLQADMDPSAESIAGVDEVGRGCWFGPVFAGAVVLTEVAAVELLAEGLTDSKALTVRRRARLVPLIE
DAATAWALGQASAREIDALGIRSATELAMLRALQRLPTPLELVLVDGVLPLRLWMGPQRTVVRGDSKCAAIAAASVLAKQ
ARDGLIKRLASRFYGYGLERHVGYGTAIHRRALLDLGPTELHRRSFLTKLFAVNGSLT

Sequences:

>Translated_218_residues
MNPRIRAAAAVAPQLQADMDPSAESIAGVDEVGRGCWFGPVFAGAVVLTEVAAVELLAEGLTDSKALTVRRRARLVPLIE
DAATAWALGQASAREIDALGIRSATELAMLRALQRLPTPLELVLVDGVLPLRLWMGPQRTVVRGDSKCAAIAAASVLAKQ
ARDGLIKRLASRFYGYGLERHVGYGTAIHRRALLDLGPTELHRRSFLTKLFAVNGSLT
>Mature_218_residues
MNPRIRAAAAVAPQLQADMDPSAESIAGVDEVGRGCWFGPVFAGAVVLTEVAAVELLAEGLTDSKALTVRRRARLVPLIE
DAATAWALGQASAREIDALGIRSATELAMLRALQRLPTPLELVLVDGVLPLRLWMGPQRTVVRGDSKCAAIAAASVLAKQ
ARDGLIKRLASRFYGYGLERHVGYGTAIHRRALLDLGPTELHRRSFLTKLFAVNGSLT

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=186, Percent_Identity=45.1612903225806, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PROMM (Q7V4Z5)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895615.1
- ProteinModelPortal:   Q7V4Z5
- SMR:   Q7V4Z5
- STRING:   Q7V4Z5
- GeneID:   1729085
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1788
- NMPDR:   fig|74547.1.peg.1782
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK13925
- BioCyc:   PMAR74547:PMT1788-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 23327; Mature: 23327

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRIRAAAAVAPQLQADMDPSAESIAGVDEVGRGCWFGPVFAGAVVLTEVAAVELLAEG
CCCCHHHHHHHHHHHHCCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LTDSKALTVRRRARLVPLIEDAATAWALGQASAREIDALGIRSATELAMLRALQRLPTPL
CCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
ELVLVDGVLPLRLWMGPQRTVVRGDSKCAAIAAASVLAKQARDGLIKRLASRFYGYGLER
EEHHHCCCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
HVGYGTAIHRRALLDLGPTELHRRSFLTKLFAVNGSLT
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNPRIRAAAAVAPQLQADMDPSAESIAGVDEVGRGCWFGPVFAGAVVLTEVAAVELLAEG
CCCCHHHHHHHHHHHHCCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LTDSKALTVRRRARLVPLIEDAATAWALGQASAREIDALGIRSATELAMLRALQRLPTPL
CCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
ELVLVDGVLPLRLWMGPQRTVVRGDSKCAAIAAASVLAKQARDGLIKRLASRFYGYGLER
EEHHHCCCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
HVGYGTAIHRRALLDLGPTELHRRSFLTKLFAVNGSLT
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642