Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 33864053

GI number: 33864053

Start: 1884882

End: 1885724

Strand: Reverse

Name: pheA [H]

Synonym: PMT1786

Alternate gene names: 33864053

Gene position: 1885724-1884882 (Counterclockwise)

Preceding gene: 33864055

Following gene: 33864044

Centisome position: 78.22

GC content: 55.04

Gene sequence:

>843_bases
ATGCCAATACGCGTGGCCTTCCTCGGACCGGAGGGAACCTATGGTCAGCAAGCGGCTCAAGCTCTGGCGGAGCTTGAGGG
ATTAGCAAATTTTGAGCTGGTGCCCTGTATAGGTCTGCGTTCCGTCGTTGAGCATGTGGCCACTAAACGCTCTGAAATGG
CGGTGGTTCCGGTGGAGAATTCCGTGGAGGGTGGTGTAACTGCCAGCTTGGATGCGCTTTGGTCTCATCCGCAGTTATGC
ATCCTTAGGGCAGTGGTTTTGCCGATTCGTCATGCTCTACTGAGCAGTGGCGGATTCAAAGACATCTCTGAAGTCCTGTC
TCATCCCCAAGCTCTGGCTCAGTGCAGTGGCTGGTTGGCTGATCATCTTCCTGATGCCCTGCAGTTGCCTACAAGTTCTA
CGGCCGAGGCGGCCAGCATGGTTATAGATAGTCGATTTCGGGCAGCGATCGCTTCTCGGCCTACGGGCCAGGGAAGAGGC
CTTAAAGAACTGGCTTTTCCTATCAACGATGTCGCGGGCAATCGCACCAGATTCCTGTTGTTACGGCAGGGAACACCGCT
GCAACGTGGGGATGTGGCCAGCTTCGCATTCTCTCTGCATGCCAACGCCCCGGGCAGCCTGCTCGAAGCACTCACTTGTG
TGGCTCGACTGGGGTTCAATATGAGTCGGATTGAGTCGCGTCCCTCGAAGCGAGAACTAGGTGAATACGTGTTCTTTGTG
GATGTGGAATTGAGGGATGGGGGTATTGGTGCATCTGAGCAGCTCATCGAGGCCTTGCAGCCTTTGTGTGAACATCTTGT
GCATTTCGGCTCTTATCTCAGCAGCGACTTGGAGCTCGATTGA

Upstream 100 bases:

>100_bases
TTACCGGCAAATTGAGGTTCTGGCAGGCTTGGAAAGCCAGAGGCATGGCTTGCGGTTGACGCGTCATGATCCTATCGACC
TCACTTGCGATGCGCTTCTG

Downstream 100 bases:

>100_bases
GATCAGTCGCGGCTGCGGAAGACACCGAATTGCATCAGACCGTGGGCAAAAGCCCAGCGCATCAACAAAATCGTTGGTAT
TTCTCTGAATCCCTTGACCA

Product: chorismate mutase-prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVVPVENSVEGGVTASLDALWSHPQLC
ILRAVVLPIRHALLSSGGFKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAEAASMVIDSRFRAAIASRPTGQGRG
LKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVARLGFNMSRIESRPSKRELGEYVFFV
DVELRDGGIGASEQLIEALQPLCEHLVHFGSYLSSDLELD

Sequences:

>Translated_280_residues
MPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVVPVENSVEGGVTASLDALWSHPQLC
ILRAVVLPIRHALLSSGGFKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAEAASMVIDSRFRAAIASRPTGQGRG
LKELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVARLGFNMSRIESRPSKRELGEYVFFV
DVELRDGGIGASEQLIEALQPLCEHLVHFGSYLSSDLELD
>Mature_279_residues
PIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVVPVENSVEGGVTASLDALWSHPQLCI
LRAVVLPIRHALLSSGGFKDISEVLSHPQALAQCSGWLADHLPDALQLPTSSTAEAASMVIDSRFRAAIASRPTGQGRGL
KELAFPINDVAGNRTRFLLLRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVARLGFNMSRIESRPSKRELGEYVFFVD
VELRDGGIGASEQLIEALQPLCEHLVHFGSYLSSDLELD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=246, Percent_Identity=32.1138211382114, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324013, Length=323, Percent_Identity=26.0061919504644, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30049; Mature: 29917

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVVPVEN
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCCCCEEEEECCC
SVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSSGGFKDISEVLSHPQALAQCSGWLA
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
DHLPDALQLPTSSTAEAASMVIDSRFRAAIASRPTGQGRGLKELAFPINDVAGNRTRFLL
HHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHCCCCCEEEEE
LRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVARLGFNMSRIESRPSKRELGEYVFFV
EECCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCEEEEE
DVELRDGGIGASEQLIEALQPLCEHLVHFGSYLSSDLELD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PIRVAFLGPEGTYGQQAAQALAELEGLANFELVPCIGLRSVVEHVATKRSEMAVVPVEN
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCCCCEEEEECCC
SVEGGVTASLDALWSHPQLCILRAVVLPIRHALLSSGGFKDISEVLSHPQALAQCSGWLA
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
DHLPDALQLPTSSTAEAASMVIDSRFRAAIASRPTGQGRGLKELAFPINDVAGNRTRFLL
HHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHCCCCCEEEEE
LRQGTPLQRGDVASFAFSLHANAPGSLLEALTCVARLGFNMSRIESRPSKRELGEYVFFV
EECCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHCCEEEEE
DVELRDGGIGASEQLIEALQPLCEHLVHFGSYLSSDLELD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]