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The map label for this gene is btuR [C]

Identifier: 33863985

GI number: 33863985

Start: 1821032

End: 1822240

Strand: Direct

Name: btuR [C]

Synonym: PMT1718

Alternate gene names: 33863985

Gene position: 1821032-1822240 (Clockwise)

Preceding gene: 33863983

Following gene: 33863988

Centisome position: 75.53

GC content: 56.74

Gene sequence:

>1209_bases
ATGGCTTCGCAGACGGCAGCATCCAAGACACCCAGAAATCGCCAAACATCAAGCGGCAGAAGAGGACGTGGGATTGGCAT
CGCGACCGCAGCCGAAAGCAATGAACGCAGTCATGGCCAACTGCACATCTATGACGGCGAGGGAAAAGGTAAAAGTCAAG
CCGCTCTTGGTGTTGTCCTTCGCACCATCGGGCTCGGGATCTGCGAGCAACGACGAACCAGGGTGCTGTTGCTTCGATTC
CTCAAAGGCCCAGGCCGCGCCTACGACGAAGATGCTGCTATTGAGGCACTGCAACAGGGCTTCCCTCACCTAATCGACCA
AGTGCGCACAGGTCGGGGTGAATTTTTCATCGCCGAGGACGCTACCCATTTTGATCGCCAAGAAGCCCAACGCGGCTGGG
ATATCGCCAAGGGAGCCATCGCCAGCGCCCTCTATTCAGTCGTTGTGCTTGATGAACTCAATCCCGTGCTGGATCTAGGC
CTGCTGGCTGTTGACGATGTGGTCAAAACACTCACCGACCGACCTGACGGCATGGAGATCATCGTCACCGGACGGGCCGC
GCCACGAGCCCTGGTTCAAGTAGCCGATCTGCATTCCGAAATGCGCGCCCATCGTCGTCCGGAGCCTCAGGATGACAGCG
TCATTCCCTTCCTTCCCACCGGTGGAATTGAGATCTACACCGGTGAGGGCAAAGGCAAATCCACCAGTGCCCTAGGCAAG
GCTCTACAGGCCATTGGCCGTGGCATCAGCCAAGACAAAAGCCATCGCGTGTTGATCTTGCAGTGGCTTAAAGGTGGCAA
TGGCTACACCGAAGACGCTGCCATTGCAGCCTTAAGAGAAAGCTATCCCCACCTTGTTGATCATCTTCGCTCCGGCCGGG
ATGCCATCGTCTGGCGAGGTCAACAACAACCGATCGATTACGTCGAAGCAGAGCGCGCATGGGAAATTGCCAGAGCCGCC
ATCGCCAGTGGGCTCTATAAAACTGTCATCCTCGATGAACTAAATCCCAGCGTGGATCTTGAACTGATTCCTGTGGAGCC
GATTGTTCAGACCCTGCTGCGCAAGCCGGCCGAAACCGAAGTCATCATCACCGGCCGCTGCAAAAACCAACCTGCCTACT
TCGATCTGGCCGGCGTCCACTCAGAAATGGTGTGCCACAAGCACTACGCCGAACAGGGCGTAGACCTCAAGCGAGGCGTG
GATTACTAA

Upstream 100 bases:

>100_bases
CAGAGGTTCCAACTGCCGAAACACCGCTGCACCAGCCGTCCCAGCAACCACCTTCTCAGCCCATCGATCTCGTTAAGCTC
CAACCGTAGAGGACCCGTCA

Downstream 100 bases:

>100_bases
GGCAATCCTCAACAAAGAAGCTTTTTAATTGACTGTCCTAAACACCTGCCTCAGCTGGTAATAATTGAAGCGGGCTGATT
GAAATCCCTTCAACAATGAG

Product: hypothetical protein

Products: Adenosylcobalamin; Phosphate; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MASQTAASKTPRNRQTSSGRRGRGIGIATAAESNERSHGQLHIYDGEGKGKSQAALGVVLRTIGLGICEQRRTRVLLLRF
LKGPGRAYDEDAAIEALQQGFPHLIDQVRTGRGEFFIAEDATHFDRQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLG
LLAVDDVVKTLTDRPDGMEIIVTGRAAPRALVQVADLHSEMRAHRRPEPQDDSVIPFLPTGGIEIYTGEGKGKSTSALGK
ALQAIGRGISQDKSHRVLILQWLKGGNGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEIARAA
IASGLYKTVILDELNPSVDLELIPVEPIVQTLLRKPAETEVIITGRCKNQPAYFDLAGVHSEMVCHKHYAEQGVDLKRGV
DY

Sequences:

>Translated_402_residues
MASQTAASKTPRNRQTSSGRRGRGIGIATAAESNERSHGQLHIYDGEGKGKSQAALGVVLRTIGLGICEQRRTRVLLLRF
LKGPGRAYDEDAAIEALQQGFPHLIDQVRTGRGEFFIAEDATHFDRQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLG
LLAVDDVVKTLTDRPDGMEIIVTGRAAPRALVQVADLHSEMRAHRRPEPQDDSVIPFLPTGGIEIYTGEGKGKSTSALGK
ALQAIGRGISQDKSHRVLILQWLKGGNGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEIARAA
IASGLYKTVILDELNPSVDLELIPVEPIVQTLLRKPAETEVIITGRCKNQPAYFDLAGVHSEMVCHKHYAEQGVDLKRGV
DY
>Mature_401_residues
ASQTAASKTPRNRQTSSGRRGRGIGIATAAESNERSHGQLHIYDGEGKGKSQAALGVVLRTIGLGICEQRRTRVLLLRFL
KGPGRAYDEDAAIEALQQGFPHLIDQVRTGRGEFFIAEDATHFDRQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLGL
LAVDDVVKTLTDRPDGMEIIVTGRAAPRALVQVADLHSEMRAHRRPEPQDDSVIPFLPTGGIEIYTGEGKGKSTSALGKA
LQAIGRGISQDKSHRVLILQWLKGGNGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEIARAAI
ASGLYKTVILDELNPSVDLELIPVEPIVQTLLRKPAETEVIITGRCKNQPAYFDLAGVHSEMVCHKHYAEQGVDLKRGVD
Y

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=211, Percent_Identity=31.2796208530806, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17 [C]

Molecular weight: Translated: 43966; Mature: 43835

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQTAASKTPRNRQTSSGRRGRGIGIATAAESNERSHGQLHIYDGEGKGKSQAALGVVL
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
RTIGLGICEQRRTRVLLLRFLKGPGRAYDEDAAIEALQQGFPHLIDQVRTGRGEFFIAED
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCEEEECC
ATHFDRQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLGLLAVDDVVKTLTDRPDGMEI
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEE
IVTGRAAPRALVQVADLHSEMRAHRRPEPQDDSVIPFLPTGGIEIYTGEGKGKSTSALGK
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCCCCHHHHHH
ALQAIGRGISQDKSHRVLILQWLKGGNGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRG
HHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
QQQPIDYVEAERAWEIARAAIASGLYKTVILDELNPSVDLELIPVEPIVQTLLRKPAETE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCCCE
VIITGRCKNQPAYFDLAGVHSEMVCHKHYAEQGVDLKRGVDY
EEEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure 
ASQTAASKTPRNRQTSSGRRGRGIGIATAAESNERSHGQLHIYDGEGKGKSQAALGVVL
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHH
RTIGLGICEQRRTRVLLLRFLKGPGRAYDEDAAIEALQQGFPHLIDQVRTGRGEFFIAED
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCEEEECC
ATHFDRQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLGLLAVDDVVKTLTDRPDGMEI
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEE
IVTGRAAPRALVQVADLHSEMRAHRRPEPQDDSVIPFLPTGGIEIYTGEGKGKSTSALGK
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCCCCHHHHHH
ALQAIGRGISQDKSHRVLILQWLKGGNGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRG
HHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
QQQPIDYVEAERAWEIARAAIASGLYKTVILDELNPSVDLELIPVEPIVQTLLRKPAETE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCCCE
VIITGRCKNQPAYFDLAGVHSEMVCHKHYAEQGVDLKRGVDY
EEEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Cob(I)alamin; H2O [C]

Specific reaction: ATP + Cob(I)alamin + H2O <==> Adenosylcobalamin + Phosphate + Diphosphate [C]

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]