Click here to switch to the map view.

The map label for this gene is speH [H]

Identifier: 33863983

GI number: 33863983

Start: 1818249

End: 1818722

Strand: Direct

Name: speH [H]

Synonym: PMT1716

Alternate gene names: 33863983

Gene position: 1818249-1818722 (Clockwise)

Preceding gene: 33863982

Following gene: 33863985

Centisome position: 75.42

GC content: 53.16

Gene sequence:

>474_bases
ATGGAGAGAACCCTGTCTTGCTTGCATCCCAATCCAGGATGGGAAGACACCAATTGCCAAGACAACACAAGCTCCATCAA
TCACAGCGCCACCGACATGGTGGGCAAGCACTGCATCCTCGAGCTTTATGACTGCGATCACGCCAAGCTCAATGACGAAG
CCTTTCTGAGAACCACGATCACAACAGCAGCCAAGCGTGCTGGTGCCACTCTTCTCAATCTGATCACCCACCGATTTGAA
CCTCAGGGGGTCACAGGGCTTGCCCTTCTAGCTGAATCGCATCTCTCCATCCACACATGGCCTGAGAATGGTTATGCCGC
GGTGGATGTCTTCACTTGCGGCGATCAAACGATGCCGGAACAAGCTTGTGAGCTCTTACGCCAGGAACTTGGCGCCAAAA
ACCATGCATTAAAGAGCTTCCAACGGGAAACACCAGCAGCTCTAGCGACCGCAGTACGCCATCCAAAGGCTTAA

Upstream 100 bases:

>100_bases
CCAGGATGAATGGCAACAACAATCACAGATCATCGAAGCAGGATCTTTAAATCGATCGGAAGAGGTCCGCTAAGGTGGCG
AGCTGATTTTTATTGCCTTG

Downstream 100 bases:

>100_bases
TCAGCTAGCTACAGCGACCTGCTTAAACCAATACTGAAGCATTTGAGTGATCGTTACAGGCACTTCTAAAAGGCAAGGTG
TATCTCAACACCTACTCACA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MERTLSCLHPNPGWEDTNCQDNTSSINHSATDMVGKHCILELYDCDHAKLNDEAFLRTTITTAAKRAGATLLNLITHRFE
PQGVTGLALLAESHLSIHTWPENGYAAVDVFTCGDQTMPEQACELLRQELGAKNHALKSFQRETPAALATAVRHPKA

Sequences:

>Translated_157_residues
MERTLSCLHPNPGWEDTNCQDNTSSINHSATDMVGKHCILELYDCDHAKLNDEAFLRTTITTAAKRAGATLLNLITHRFE
PQGVTGLALLAESHLSIHTWPENGYAAVDVFTCGDQTMPEQACELLRQELGAKNHALKSFQRETPAALATAVRHPKA
>Mature_157_residues
MERTLSCLHPNPGWEDTNCQDNTSSINHSATDMVGKHCILELYDCDHAKLNDEAFLRTTITTAAKRAGATLLNLITHRFE
PQGVTGLALLAESHLSIHTWPENGYAAVDVFTCGDQTMPEQACELLRQELGAKNHALKSFQRETPAALATAVRHPKA

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 17250; Mature: 17250

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTLSCLHPNPGWEDTNCQDNTSSINHSATDMVGKHCILELYDCDHAKLNDEAFLRTTI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEHEECCCCCCCCCCHHHHHHH
TTAAKRAGATLLNLITHRFEPQGVTGLALLAESHLSIHTWPENGYAAVDVFTCGDQTMPE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCHH
QACELLRQELGAKNHALKSFQRETPAALATAVRHPKA
HHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MERTLSCLHPNPGWEDTNCQDNTSSINHSATDMVGKHCILELYDCDHAKLNDEAFLRTTI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEHEECCCCCCCCCCHHHHHHH
TTAAKRAGATLLNLITHRFEPQGVTGLALLAESHLSIHTWPENGYAAVDVFTCGDQTMPE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCHH
QACELLRQELGAKNHALKSFQRETPAALATAVRHPKA
HHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]