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The map label for this gene is ubiA [H]

Identifier: 33863595

GI number: 33863595

Start: 1413203

End: 1414096

Strand: Direct

Name: ubiA [H]

Synonym: PMT1328

Alternate gene names: 33863595

Gene position: 1413203-1414096 (Clockwise)

Preceding gene: 33863593

Following gene: 33863596

Centisome position: 58.62

GC content: 57.38

Gene sequence:

>894_bases
GTGACCAGCAGATCCTTCTCCAATGGCTTAAGGCAATGGCTAGAGCTGCTGCGATGGCACAAACCCAGTGGTCGGCTCAT
CCTTCTCGTGCCAGCAGGTTGGAGCCTTTGGCTCACTCCAGATGCACCTCCTTTAGCAGGGCTTGTGAGTCTGATCGTCG
TTGGAGGTCTGATGGTGAGCGGCGCCGGTTGCATTGCCAATGATCTCTGGGATCGACGCATTGATCGCCAGGTGGAACGC
ACCAGGGAACGGCCACTAGCGAAGGGCAGCATTCGAATTTGCACTGCTGTGGGCTTATTGATTGTGTTGTTGCTGCTCAG
TCTTTTGGTCGTGGCCTCCCTGCCAACGCCAAGCCAGCGCCTATGCCTTGCTCTAGCCATCCTGGCCTTGCCACCGATCC
TGCTCTACCCCTCGGCCAAGCGCTGGTTTGCCTATCCACAAGCGGTGCTTGCCCTCTGCTGGGGGTTTGCCGTACTGATC
CCCTGGGCAGCAAGCCAGGCCAATCTCAAAGGAGGCTGGCCACTGCTGGGCTGCTGGTTGGCCACTCTGATGTGGACGTT
CGGCTTTGACACGGTTTACGCCATGGCGGATCGTCGTGACGACGCCAACCTGGCCTTAAAAAGCAGTGCTTTGAGCCTGG
GGAGCCATGCACTTAAAACTGTCGCGTTTAGTTATGCACTGGCCTGCACCTTTTTGGCTAGTTCAGCAGTGAGCGCAGGA
GTGGGCTGGGCCTTTTGGCCCTTCTGGCTCATCGCCAGCATCGGCATGCAAAAAGAAACGTGGACCCTGCGAGGTTCCAA
TCAACCAATTACGACCTACGGGCAGCACTTTCAGCATCAAGTTCTGCTAGGCGCAATGTTGCTGCTCGGCTTGATCCTGG
GGCGCATCAGCTGA

Upstream 100 bases:

>100_bases
ACACCTGGCATGAAGTACAGGAGCCTGGAACGAGACCACTTTGCCATCAGCCAACGATGTCTGGAGGTCCCTCCCTAGGG
TTCTTCAAACCCAGAAACCC

Downstream 100 bases:

>100_bases
ATCATGGTGCAGCTCCGATCTAACCTGCTCACACCAGCGCTTCAACGTGGCGACGAGGTGGTCACAGTGGCTGCGAGTTC
AGCGCTGGATGATGAACAAT

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTSRSFSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVSGAGCIANDLWDRRIDRQVER
TRERPLAKGSIRICTAVGLLIVLLLLSLLVVASLPTPSQRLCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLI
PWAASQANLKGGWPLLGCWLATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASSAVSAG
VGWAFWPFWLIASIGMQKETWTLRGSNQPITTYGQHFQHQVLLGAMLLLGLILGRIS

Sequences:

>Translated_297_residues
MTSRSFSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVSGAGCIANDLWDRRIDRQVER
TRERPLAKGSIRICTAVGLLIVLLLLSLLVVASLPTPSQRLCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLI
PWAASQANLKGGWPLLGCWLATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASSAVSAG
VGWAFWPFWLIASIGMQKETWTLRGSNQPITTYGQHFQHQVLLGAMLLLGLILGRIS
>Mature_296_residues
TSRSFSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVSGAGCIANDLWDRRIDRQVERT
RERPLAKGSIRICTAVGLLIVLLLLSLLVVASLPTPSQRLCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLIP
WAASQANLKGGWPLLGCWLATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASSAVSAGV
GWAFWPFWLIASIGMQKETWTLRGSNQPITTYGQHFQHQVLLGAMLLLGLILGRIS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=293, Percent_Identity=30.3754266211604, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1790473, Length=288, Percent_Identity=31.25, Blast_Score=124, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17553718, Length=213, Percent_Identity=34.7417840375587, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32565247, Length=213, Percent_Identity=33.8028169014084, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17553720, Length=188, Percent_Identity=32.9787234042553, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32565245, Length=144, Percent_Identity=37.5, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=144, Percent_Identity=37.5, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324370, Length=299, Percent_Identity=28.0936454849498, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21355567, Length=290, Percent_Identity=32.4137931034483, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32418; Mature: 32287

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRSFSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVS
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHC
GAGCIANDLWDRRIDRQVERTRERPLAKGSIRICTAVGLLIVLLLLSLLVVASLPTPSQR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLIPWAASQANLKGGWPLLGCWL
HHHHHHHHHHCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASSAVSAG
HHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGWAFWPFWLIASIGMQKETWTLRGSNQPITTYGQHFQHQVLLGAMLLLGLILGRIS
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSRSFSNGLRQWLELLRWHKPSGRLILLVPAGWSLWLTPDAPPLAGLVSLIVVGGLMVS
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHC
GAGCIANDLWDRRIDRQVERTRERPLAKGSIRICTAVGLLIVLLLLSLLVVASLPTPSQR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LCLALAILALPPILLYPSAKRWFAYPQAVLALCWGFAVLIPWAASQANLKGGWPLLGCWL
HHHHHHHHHHCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ATLMWTFGFDTVYAMADRRDDANLALKSSALSLGSHALKTVAFSYALACTFLASSAVSAG
HHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGWAFWPFWLIASIGMQKETWTLRGSNQPITTYGQHFQHQVLLGAMLLLGLILGRIS
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA