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The map label for this gene is trpD

Identifier: 33862927

GI number: 33862927

Start: 708508

End: 709563

Strand: Reverse

Name: trpD

Synonym: PMT0654

Alternate gene names: 33862927

Gene position: 709563-708508 (Counterclockwise)

Preceding gene: 33862929

Following gene: 33862926

Centisome position: 29.43

GC content: 55.59

Gene sequence:

>1056_bases
ATGCCTACTTCAGTTACTGCCTCTTCCTCTTGGTCGCAAATCCTCGAGATGTTGCTCGAGGGACAAAACCTTCCTGAGGT
GGAAGCAACTGCCTTGATGGAGGCTTGGTTGGCGGAACAACTAACCCCTGTGCAGACCGGTGCGTTTCTAGCGGCTTTAC
GAGCCAAGGGGGTAACAGGAAATGAGTTATCAGGCATGGCCCAGGTGTTGCGAGGTGCTTGTCCCTTGCCTTGCCCATTG
CCAGACATCCCTATGGTCGACACTTGTGGAACAGGTGGCGACGGTGCAGACACCTTCAACATCTCAACCGCAGTGGCGTT
TACTGCTGCCGCCTGCGGGGCGAATGTGGCTAAGCATGGCAATCGCAGTGCAAGTGGCAAAGTCGGTTCAGCAGATGTTC
TTGAGGGCCTGGGTCTACAGCTCAAGGCCCCTCTTGTCTCCGTGGTGGAGGCCCTGGTTGAGGTAGGCGTCACATTTTTA
TTTGCCCCAGCCTGGCACCCCGCTTTGGTCAACTTGGCCCCGTTGCGGCGCAGCCTTGGAGTGCGCACCGTCTTCAATCT
TCTGGGTCCACTGGTGAATCCTTTGCAACCAAATGCCCAGGTTCTCGGGGTAGCTAAGGCTGAGCTGCTCAATCCAATGG
CGGAAGCATTGCAACGGCTTGGCTTGCAGCGGGCCGTTGTTGTCCATGGCGCTGGAGGCCTTGATGAAGCGTCGTTGGAG
GGAGCCAATGCAATGCGTTTGCTTGAGAATGGTCACTTACGACAAGCATCGATCGATTCGGCAGAACTCGGGCTTACTAG
AGCTCCTTTGCAGGCTCTCCAGGGTGGTGATTTGGCAACAAATCAAGCGATTCTTTCCGCTGTACTTCAGGGAGGTGGTA
CCGCCCCTCAACGGGATGTGGTGGCATTGAACACAGCCCTAGTGCTCTGGGCTGCTGGCCTACAAGATGATTTACAAGCA
GGTGTTTCTACTGCAAAGACTTGCCTGCAGGAAGGCCTCCCCTGGCAACGGCTAGAAGGGCTCCGCATGGCACTTGATCA
TCAAATTGGAGAATGA

Upstream 100 bases:

>100_bases
CTTGTAGAAATTCTCGCCAGTAGCAAAGTTTTAGGGGATAGTGGTGTTGTCCCCATCACCCAGCCCGGAGTGCTTTGCAC
CCGGGTTTTTTTCTGCTCCG

Downstream 100 bases:

>100_bases
GACTGCGATGACTTCGGGATCCTTCTGCTGATGATTGCTTCATCGCGAAATTCGGCGCTCTTGATGCTTGCTGATGGAAC
GGTGCTTGAGGGGGAGGCCT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPTSVTASSSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTGNELSGMAQVLRGACPLPCPL
PDIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQLKAPLVSVVEALVEVGVTFL
FAPAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLGLQRAVVVHGAGGLDEASLE
GANAMRLLENGHLRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDVVALNTALVLWAAGLQDDLQA
GVSTAKTCLQEGLPWQRLEGLRMALDHQIGE

Sequences:

>Translated_351_residues
MPTSVTASSSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTGNELSGMAQVLRGACPLPCPL
PDIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQLKAPLVSVVEALVEVGVTFL
FAPAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLGLQRAVVVHGAGGLDEASLE
GANAMRLLENGHLRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDVVALNTALVLWAAGLQDDLQA
GVSTAKTCLQEGLPWQRLEGLRMALDHQIGE
>Mature_350_residues
PTSVTASSSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTGNELSGMAQVLRGACPLPCPLP
DIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQLKAPLVSVVEALVEVGVTFLF
APAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLGLQRAVVVHGAGGLDEASLEG
ANAMRLLENGHLRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDVVALNTALVLWAAGLQDDLQAG
VSTAKTCLQEGLPWQRLEGLRMALDHQIGE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=335, Percent_Identity=40.8955223880597, Blast_Score=214, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6320561, Length=324, Percent_Identity=29.320987654321, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PROMM (Q7TV05)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_894487.1
- ProteinModelPortal:   Q7TV05
- SMR:   Q7TV05
- STRING:   Q7TV05
- GeneID:   1728385
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT0654
- NMPDR:   fig|74547.1.peg.654
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   PMAR74547:PMT0654-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36205; Mature: 36074

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSVTASSSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTG
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
NELSGMAQVLRGACPLPCPLPDIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCHHHHCC
NRSASGKVGSADVLEGLGLQLKAPLVSVVEALVEVGVTFLFAPAWHPALVNLAPLRRSLG
CCCCCCCCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLGLQRAVVVHGAGGLDEASLE
HHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHCC
GANAMRLLENGHLRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDV
CHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCH
VALNTALVLWAAGLQDDLQAGVSTAKTCLQEGLPWQRLEGLRMALDHQIGE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTSVTASSSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTG
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
NELSGMAQVLRGACPLPCPLPDIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCHHHHCC
NRSASGKVGSADVLEGLGLQLKAPLVSVVEALVEVGVTFLFAPAWHPALVNLAPLRRSLG
CCCCCCCCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLGLQRAVVVHGAGGLDEASLE
HHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHCC
GANAMRLLENGHLRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDV
CHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCH
VALNTALVLWAAGLQDDLQAGVSTAKTCLQEGLPWQRLEGLRMALDHQIGE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642