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The map label for this gene is cmoA

Identifier: 32267351

GI number: 32267351

Start: 1774672

End: 1775391

Strand: Direct

Name: cmoA

Synonym: HH1852

Alternate gene names: 32267351

Gene position: 1774672-1775391 (Clockwise)

Preceding gene: 32267350

Following gene: 32267352

Centisome position: 98.64

GC content: 35.14

Gene sequence:

>720_bases
ATGAAAGATAGAATCTTTAAACAAGATATTGGCAAACAATTTGAATTTGATGCGCAAGTAGCAAGTGTGTTTGATGATAT
GCTTGAGCGTTCAATTCCTCATTATAAAGAGGTGTTAGGTTTAATTGTAGATTTTTGCTCCTATACTTTAGAATCTTCTA
AAAGTGCTATACCTCTTGTTTATGATTTAGGAAGCTCCACAGGAACGACACTTTTAGCTCTCTCTCAAGCTTTATCAACA
CATACACGCTTTATTGGTATTGATAGTTCTCAAGCTATGATTGATAAAGCCTCACTTAAAGCTCAAGCCTATAACGCGAA
CATTGAATTTATCTGCACAGACTTGCTTGAATACGATTTTTTGCACTCTGATATTGTAATTGCTAATTATAGCTTACAAT
TTATCCGCCCAATGCAACGCCCTGCACTTCTGCAAAAAATTTACAATGCTCTTACGGAGGGAGGAATTTTAATTGTGAGC
GAAAAGATGACTTCTCATCATAGAATCCTTGATAGGCAAATGATAGAACGATATGTTCGCTATAAACAAGAGCAAGGCTA
CACAAAAACCGAAATTAGCAAAAAGCGTGAAGCATTAGAAAATGTGCTTGTGCCTTTTAGCCTTGAAGAAAATATTGCAA
TGCTTAAAGATATAGGTTTTAGTGGCATTGAGGTGCTTTTTAAATGGGTGAATTTTGGCACTTTGATTGCTAAAAAGTAA

Upstream 100 bases:

>100_bases
ATTAAGCTATCTTGCTGGACGCATACCACGTAAAGCCTATGCAAGTGCAAGTTCTCCACTTGAAGGTATGATGCAATTTG
GTTAGATTCTAGGCAAAATA

Downstream 100 bases:

>100_bases
TAAATATTTATATTTTATATGTATTTATTTTATGCAAACTAAAATTATAAAAGAAAAATAATGTAATTTATTGTAACTTA
TTTTAAAATTTTACTAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKDRIFKQDIGKQFEFDAQVASVFDDMLERSIPHYKEVLGLIVDFCSYTLESSKSAIPLVYDLGSSTGTTLLALSQALST
HTRFIGIDSSQAMIDKASLKAQAYNANIEFICTDLLEYDFLHSDIVIANYSLQFIRPMQRPALLQKIYNALTEGGILIVS
EKMTSHHRILDRQMIERYVRYKQEQGYTKTEISKKREALENVLVPFSLEENIAMLKDIGFSGIEVLFKWVNFGTLIAKK

Sequences:

>Translated_239_residues
MKDRIFKQDIGKQFEFDAQVASVFDDMLERSIPHYKEVLGLIVDFCSYTLESSKSAIPLVYDLGSSTGTTLLALSQALST
HTRFIGIDSSQAMIDKASLKAQAYNANIEFICTDLLEYDFLHSDIVIANYSLQFIRPMQRPALLQKIYNALTEGGILIVS
EKMTSHHRILDRQMIERYVRYKQEQGYTKTEISKKREALENVLVPFSLEENIAMLKDIGFSGIEVLFKWVNFGTLIAKK
>Mature_239_residues
MKDRIFKQDIGKQFEFDAQVASVFDDMLERSIPHYKEVLGLIVDFCSYTLESSKSAIPLVYDLGSSTGTTLLALSQALST
HTRFIGIDSSQAMIDKASLKAQAYNANIEFICTDLLEYDFLHSDIVIANYSLQFIRPMQRPALLQKIYNALTEGGILIVS
EKMTSHHRILDRQMIERYVRYKQEQGYTKTEISKKREALENVLVPFSLEENIAMLKDIGFSGIEVLFKWVNFGTLIAKK

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=243, Percent_Identity=33.7448559670782, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_HELHP (Q7VF27)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_861383.1
- HSSP:   P43985
- ProteinModelPortal:   Q7VF27
- SMR:   Q7VF27
- GeneID:   1492399
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH1852
- NMPDR:   fig|235279.1.peg.1852
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK2758452
- BioCyc:   HHEP235279:HH_1852-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013217
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08242 Methyltransf_12

EC number: NA

Molecular weight: Translated: 27254; Mature: 27254

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: BINDING 35-35 BINDING 88-88 BINDING 129-129 BINDING 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRIFKQDIGKQFEFDAQVASVFDDMLERSIPHYKEVLGLIVDFCSYTLESSKSAIPLV
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
YDLGSSTGTTLLALSQALSTHTRFIGIDSSQAMIDKASLKAQAYNANIEFICTDLLEYDF
EECCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LHSDIVIANYSLQFIRPMQRPALLQKIYNALTEGGILIVSEKMTSHHRILDRQMIERYVR
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHH
YKQEQGYTKTEISKKREALENVLVPFSLEENIAMLKDIGFSGIEVLFKWVNFGTLIAKK
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDRIFKQDIGKQFEFDAQVASVFDDMLERSIPHYKEVLGLIVDFCSYTLESSKSAIPLV
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
YDLGSSTGTTLLALSQALSTHTRFIGIDSSQAMIDKASLKAQAYNANIEFICTDLLEYDF
EECCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LHSDIVIANYSLQFIRPMQRPALLQKIYNALTEGGILIVSEKMTSHHRILDRQMIERYVR
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHH
YKQEQGYTKTEISKKREALENVLVPFSLEENIAMLKDIGFSGIEVLFKWVNFGTLIAKK
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954