Click here to switch to the map view.

The map label for this gene is plsC

Identifier: 32267122

GI number: 32267122

Start: 1545498

End: 1546226

Strand: Direct

Name: plsC

Synonym: HH1623

Alternate gene names: 32267122

Gene position: 1545498-1546226 (Clockwise)

Preceding gene: 32267121

Following gene: 32267123

Centisome position: 85.9

GC content: 37.45

Gene sequence:

>729_bases
ATGTTAGCAAAAATTAGAGCATTTCTTGCCACTCTCTCCATCGCCATTTATCTTCCCGTCATTATTGCCCAAATCTATCT
TACGCGTAGTTGGCGTAATGGTAGATGGGCAAGAAAGCAATGTCGTTGGTTTTTTGGATTTAATAGATTGAATGTAGAGC
GTATAGGTGAATATGATAAAGATGCACAACTTTTTGTTGTCAATCATCAGAGCGTAACAGATATTATTTATTTTGAGGGA
TTTCACCCTGCAAATTTGTGTTGGGTGGCTAAAAAACAGCTTGGGGAAATACCTTTATATGGGCACGCACTCAAAGCTCC
AGATATGATACTCATTGATAGGGAAGATAAAAAAAGTATCGTCTTTTTGCTTAAAGAAGCAAAAAGGCAGCTTGCTCAAA
ATCGTCTTATTGCCATTTTTCCTGAAGGCACAAGGAGCGATGGAGGGGAAGAATTTTTACCTTTTAAATCGGGAGCAAAG
ATTCTCGCATCAAAGCTTAAACTTAGAATCCAGCCCGCAGTTCTTATTAATATGCGTAAGCTATATAATAGTTCATCTAT
GTCAATAGAGTCAGATAAAGCGCGAGTGGTTCTTATGGAGGCTTTTATACCAGATTTTGATGATGAGCAATGGTACGAAA
AACTCCAAAAGAATATGCACGATGTGTATTTGAAACATTATTATGAGCTCAATCAGAAGCCTTTAAGTAATAACAAGGCA
GAATCCTAG

Upstream 100 bases:

>100_bases
GAAGTAGTCAAAACACCCATAGAAGTAGCAATTATTGGCGAATATGGAGATTATTATAAAGTAATGATAGAAAATCGTGT
AGGTTGGATAAGGAAAGAAT

Downstream 100 bases:

>100_bases
CCTTAAGATTTTGGGGTGTTAGCTCAGTTGGGAGAGCGCAACGCTGGCAGCGTTGAGGTCAGGGGTTCGAACCCCCTACA
CTCCACCATTGTTTTCTATG

Product: 1-acyl-glycerol-3-phosphate acyltransferase PlsC

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLAKIRAFLATLSIAIYLPVIIAQIYLTRSWRNGRWARKQCRWFFGFNRLNVERIGEYDKDAQLFVVNHQSVTDIIYFEG
FHPANLCWVAKKQLGEIPLYGHALKAPDMILIDREDKKSIVFLLKEAKRQLAQNRLIAIFPEGTRSDGGEEFLPFKSGAK
ILASKLKLRIQPAVLINMRKLYNSSSMSIESDKARVVLMEAFIPDFDDEQWYEKLQKNMHDVYLKHYYELNQKPLSNNKA
ES

Sequences:

>Translated_242_residues
MLAKIRAFLATLSIAIYLPVIIAQIYLTRSWRNGRWARKQCRWFFGFNRLNVERIGEYDKDAQLFVVNHQSVTDIIYFEG
FHPANLCWVAKKQLGEIPLYGHALKAPDMILIDREDKKSIVFLLKEAKRQLAQNRLIAIFPEGTRSDGGEEFLPFKSGAK
ILASKLKLRIQPAVLINMRKLYNSSSMSIESDKARVVLMEAFIPDFDDEQWYEKLQKNMHDVYLKHYYELNQKPLSNNKA
ES
>Mature_242_residues
MLAKIRAFLATLSIAIYLPVIIAQIYLTRSWRNGRWARKQCRWFFGFNRLNVERIGEYDKDAQLFVVNHQSVTDIIYFEG
FHPANLCWVAKKQLGEIPLYGHALKAPDMILIDREDKKSIVFLLKEAKRQLAQNRLIAIFPEGTRSDGGEEFLPFKSGAK
ILASKLKLRIQPAVLINMRKLYNSSSMSIESDKARVVLMEAFIPDFDDEQWYEKLQKNMHDVYLKHYYELNQKPLSNNKA
ES

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=236, Percent_Identity=26.271186440678, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=172, Percent_Identity=30.8139534883721, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28203; Mature: 28203

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKIRAFLATLSIAIYLPVIIAQIYLTRSWRNGRWARKQCRWFFGFNRLNVERIGEYDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCC
DAQLFVVNHQSVTDIIYFEGFHPANLCWVAKKQLGEIPLYGHALKAPDMILIDREDKKSI
CCEEEEEECCCEEEEEEECCCCCCHHHHEEHHHHCCCCCCCCCCCCCCEEEEECCCCHHH
VFLLKEAKRQLAQNRLIAIFPEGTRSDGGEEFLPFKSGAKILASKLKLRIQPAVLINMRK
HHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHEECHHHHHHHHH
LYNSSSMSIESDKARVVLMEAFIPDFDDEQWYEKLQKNMHDVYLKHYYELNQKPLSNNKA
HHCCCCCCEECCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ES
CC
>Mature Secondary Structure
MLAKIRAFLATLSIAIYLPVIIAQIYLTRSWRNGRWARKQCRWFFGFNRLNVERIGEYDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCC
DAQLFVVNHQSVTDIIYFEGFHPANLCWVAKKQLGEIPLYGHALKAPDMILIDREDKKSI
CCEEEEEECCCEEEEEEECCCCCCHHHHEEHHHHCCCCCCCCCCCCCCEEEEECCCCHHH
VFLLKEAKRQLAQNRLIAIFPEGTRSDGGEEFLPFKSGAKILASKLKLRIQPAVLINMRK
HHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHEECHHHHHHHHH
LYNSSSMSIESDKARVVLMEAFIPDFDDEQWYEKLQKNMHDVYLKHYYELNQKPLSNNKA
HHCCCCCCEECCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ES
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]