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The map label for this gene is secA

Identifier: 161546634

GI number: 161546634

Start: 312635

End: 315190

Strand: Direct

Name: secA

Synonym: HH0317

Alternate gene names: 161546634

Gene position: 312635-315190 (Clockwise)

Preceding gene: 32265811

Following gene: 32265817

Centisome position: 17.38

GC content: 37.44

Gene sequence:

>2556_bases
ATGTTGCAAACTCTTATTTCAAAATTTCTTGGCTCACGCAACAATAAACTCATTAAACATTATCTTAAAGAAGTCCAAGC
CATTAATGCTTTAGAATCTACTTACAATACTCTAAGTGATGCACAACTGCAAGAGGCTTTTATGCAATTAAGAAAACTTA
TCCAAAATGGCGAAACCTCACTTCAATCAATTCTACATAAAAGCTTTGCAATCACACGCGAAGCAAGCAAAAGAGTGCTA
GGTATGCGGCATTTTGATGTGCAACTTATCGGTGGTATGGCACTTAATGATGGACGTATCGCTGAAATGAAAACAGGAGA
GGGCAAAACGCTTGTGGCAACTCTTGCAGTATGTCTTAATGCACTCTGTGGTAGGGGTGTGCACGTTGTAACAGTTAATG
ATTATCTTGCCAATAGAGATGCCAAAGAATTAGAACCACTTTATAATTTTCTGGGCTTTGAAGTAGGTATTATTACAAGT
GAAGTCCGCGATGATAATGAACGTTTGCAAGCATATGCGTGTGATATTGTTTATGGCACAAATAATGAATTTGGCTTTGA
TTATTTGCGAGACAATATGAAATATGACCTTTCTCAAAAAGTGCAAGGAGAGCACTATTTTGCGATTATTGACGAGGTAG
ATTCTATCCTTATTGATGAAGCACGCACACCTCTTATCATCTCTGGACCTGTTAATCGCACACTTGAACACTACCAGCTC
GCCAATAGCGTAGCTCAAAGGCTCAAAAACGAAGAAGATTTTAGCATTGATGAAAAAAATCGCGTTATTCTCCTCAATGA
AGAAGGCATTAAAAAGGCTGAGAGTCTTTTTAAAGTAGATAATCTTTATAGTATTGAAAATGCTGCACTCTCTCATCATC
TTGACCAAGCACTCAAGGCAAATTATCTTTTTATTAAAGATAAAGACTATGTTGTGCAAAATGATGAAGTAGTCATTGTT
GATGAATTTACGGGGCGTTTAAGCGAAGGCAGACGATTTAGTGAGGGATTACATCAAGCAATTGAGGCAAAAGAAAAGGT
TGATATTAAAGAGGAAAGTCAAACACTTGCAGATATTACTTTCCAAAATTATTTTCGTCTTTATGAAAAGCTCTCTGGTA
TGACAGGTACAGCGCAAACAGAAGCAAGTGAATTTTTGCAAATTTACAACCTTGAAGTAGTGAGTATTCCTACAAATGTC
CCTGTGCAGCGCAAAGACCTCAATGACCTTATTTATAAAAGTGAGAAAGAGAAATTTAATGCTGTTATTGACAAGATTCA
AGAGCTTTACAAAAAAGGGCAGCCTGTCCTTGTAGGAACTGCAAGTATTGAAAAAAGTGAGATTCTCCACGAACTTCTTA
AAAAACATAGAATCCCTCACACTGTCTTAAATGCCAAACAGCACACCAAAGAAGCCGAAATTATTAAAGACGCTGGAGTA
AAAGGCGCAGTAACAATCGCTACAAATATGGCAGGACGCGGTGTAGATATTAAAATCAATGACGAAATACGCGAACTTGG
CGGATTATATATTATTGGGACAGAGCGACACGAAAGCCGCCGCATTGATAACCAATTACGCGGAAGAGCTGGGCGACAAG
GCGACCCGGGCATTAGTCAATTCTATTTGAGCCTTGAAGATTCGCTACTTAGAATCTTTGGGAGTGATAAGATTAAGGGC
ATTATGGAGCGTCTTGGGCTTAAAGAGGGCGAACATATAGAATCTGGACTTGTTACGCGTTCAGTAGAAAGTGCACAAAA
AAAGGTAGAAAATCTCCATTTTGAATCACGCAAGCATTTGCTTGAATATGATGATGTTGCTAATGAGCAACGCAAAGCTG
TATATAAACTACGTAACGAATTGCTTGATGAAAATTGCTCATTGCAAGAGCGAATTAGCACTAATCGCGAACTCACTGCG
CAATCTATGCTTTATAAAGCCCAAATTTTACCCGGCGATGATAGCAGTAATTTCAATATAGATTCACTCAAAGCACAAAT
CAATGAAGAGCTTGGGCTTGAGATTGGAAATTGTGAGAATCTTGATTATGATGAATTACTTGAAAAACTCATTACACAAA
TGAATACAGCCTATGAGGAAAAAATGTCAAAACTTGAAGAATCTCAACGCGCCCAAATTGAACGTATTATTTACTTACAA
GTGCTTGATAGCTCGTGGCGGGAACATCTTTACACAATGGATAATCTTAAAACAGGCATAGGGCTTCGCGGGTATAATCA
AAAAGACCCGCTCGTTGAATACAAAAAAGAAAGTTATAATCTTTTCTTAGAATTTGTAGAGAATCTTAAATTTGAAACAA
CTAAAATGCTACAAATTATCCAATTAAGAGACAAAGAAGAGGAAGTAGCAAATAAAATGATAAAAAATTTGCAAGATGAA
CTTGAAGAAAACTTGCAAGATTTAAATACCAATATGGATTCTACACCTGTGCGAAAGAACAAAATTGCACGCAATGACCC
TTGTCCTTGCGGTAGTGGCAAAAAATACAAAGTATGCCACGGCAAAAGCGGACCTAAAAGTGGATTACTTGCATAA

Upstream 100 bases:

>100_bases
TAAAATTTAAGAGCAAGATTTTACCGAAAGTATGCTAAAATTATGCCCAATTTTTCAAGGTTTATTCCGCTAAACCCAAT
TTTGCTAAAAAGGCTTATCT

Downstream 100 bases:

>100_bases
ATGAAGACACTTATTTTTTATCTCTTGCCCCGTTATTTACGTTTTGACAAAACACAACCTTTCATTTCTATCACGGCACT
CTTAGCATTTTTTGGTGTGG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 851; Mature: 851

Protein sequence:

>851_residues
MLQTLISKFLGSRNNKLIKHYLKEVQAINALESTYNTLSDAQLQEAFMQLRKLIQNGETSLQSILHKSFAITREASKRVL
GMRHFDVQLIGGMALNDGRIAEMKTGEGKTLVATLAVCLNALCGRGVHVVTVNDYLANRDAKELEPLYNFLGFEVGIITS
EVRDDNERLQAYACDIVYGTNNEFGFDYLRDNMKYDLSQKVQGEHYFAIIDEVDSILIDEARTPLIISGPVNRTLEHYQL
ANSVAQRLKNEEDFSIDEKNRVILLNEEGIKKAESLFKVDNLYSIENAALSHHLDQALKANYLFIKDKDYVVQNDEVVIV
DEFTGRLSEGRRFSEGLHQAIEAKEKVDIKEESQTLADITFQNYFRLYEKLSGMTGTAQTEASEFLQIYNLEVVSIPTNV
PVQRKDLNDLIYKSEKEKFNAVIDKIQELYKKGQPVLVGTASIEKSEILHELLKKHRIPHTVLNAKQHTKEAEIIKDAGV
KGAVTIATNMAGRGVDIKINDEIRELGGLYIIGTERHESRRIDNQLRGRAGRQGDPGISQFYLSLEDSLLRIFGSDKIKG
IMERLGLKEGEHIESGLVTRSVESAQKKVENLHFESRKHLLEYDDVANEQRKAVYKLRNELLDENCSLQERISTNRELTA
QSMLYKAQILPGDDSSNFNIDSLKAQINEELGLEIGNCENLDYDELLEKLITQMNTAYEEKMSKLEESQRAQIERIIYLQ
VLDSSWREHLYTMDNLKTGIGLRGYNQKDPLVEYKKESYNLFLEFVENLKFETTKMLQIIQLRDKEEEVANKMIKNLQDE
LEENLQDLNTNMDSTPVRKNKIARNDPCPCGSGKKYKVCHGKSGPKSGLLA

Sequences:

>Translated_851_residues
MLQTLISKFLGSRNNKLIKHYLKEVQAINALESTYNTLSDAQLQEAFMQLRKLIQNGETSLQSILHKSFAITREASKRVL
GMRHFDVQLIGGMALNDGRIAEMKTGEGKTLVATLAVCLNALCGRGVHVVTVNDYLANRDAKELEPLYNFLGFEVGIITS
EVRDDNERLQAYACDIVYGTNNEFGFDYLRDNMKYDLSQKVQGEHYFAIIDEVDSILIDEARTPLIISGPVNRTLEHYQL
ANSVAQRLKNEEDFSIDEKNRVILLNEEGIKKAESLFKVDNLYSIENAALSHHLDQALKANYLFIKDKDYVVQNDEVVIV
DEFTGRLSEGRRFSEGLHQAIEAKEKVDIKEESQTLADITFQNYFRLYEKLSGMTGTAQTEASEFLQIYNLEVVSIPTNV
PVQRKDLNDLIYKSEKEKFNAVIDKIQELYKKGQPVLVGTASIEKSEILHELLKKHRIPHTVLNAKQHTKEAEIIKDAGV
KGAVTIATNMAGRGVDIKINDEIRELGGLYIIGTERHESRRIDNQLRGRAGRQGDPGISQFYLSLEDSLLRIFGSDKIKG
IMERLGLKEGEHIESGLVTRSVESAQKKVENLHFESRKHLLEYDDVANEQRKAVYKLRNELLDENCSLQERISTNRELTA
QSMLYKAQILPGDDSSNFNIDSLKAQINEELGLEIGNCENLDYDELLEKLITQMNTAYEEKMSKLEESQRAQIERIIYLQ
VLDSSWREHLYTMDNLKTGIGLRGYNQKDPLVEYKKESYNLFLEFVENLKFETTKMLQIIQLRDKEEEVANKMIKNLQDE
LEENLQDLNTNMDSTPVRKNKIARNDPCPCGSGKKYKVCHGKSGPKSGLLA
>Mature_851_residues
MLQTLISKFLGSRNNKLIKHYLKEVQAINALESTYNTLSDAQLQEAFMQLRKLIQNGETSLQSILHKSFAITREASKRVL
GMRHFDVQLIGGMALNDGRIAEMKTGEGKTLVATLAVCLNALCGRGVHVVTVNDYLANRDAKELEPLYNFLGFEVGIITS
EVRDDNERLQAYACDIVYGTNNEFGFDYLRDNMKYDLSQKVQGEHYFAIIDEVDSILIDEARTPLIISGPVNRTLEHYQL
ANSVAQRLKNEEDFSIDEKNRVILLNEEGIKKAESLFKVDNLYSIENAALSHHLDQALKANYLFIKDKDYVVQNDEVVIV
DEFTGRLSEGRRFSEGLHQAIEAKEKVDIKEESQTLADITFQNYFRLYEKLSGMTGTAQTEASEFLQIYNLEVVSIPTNV
PVQRKDLNDLIYKSEKEKFNAVIDKIQELYKKGQPVLVGTASIEKSEILHELLKKHRIPHTVLNAKQHTKEAEIIKDAGV
KGAVTIATNMAGRGVDIKINDEIRELGGLYIIGTERHESRRIDNQLRGRAGRQGDPGISQFYLSLEDSLLRIFGSDKIKG
IMERLGLKEGEHIESGLVTRSVESAQKKVENLHFESRKHLLEYDDVANEQRKAVYKLRNELLDENCSLQERISTNRELTA
QSMLYKAQILPGDDSSNFNIDSLKAQINEELGLEIGNCENLDYDELLEKLITQMNTAYEEKMSKLEESQRAQIERIIYLQ
VLDSSWREHLYTMDNLKTGIGLRGYNQKDPLVEYKKESYNLFLEFVENLKFETTKMLQIIQLRDKEEEVANKMIKNLQDE
LEENLQDLNTNMDSTPVRKNKIARNDPCPCGSGKKYKVCHGKSGPKSGLLA

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=903, Percent_Identity=48.7264673311185, Blast_Score=823, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_HELHP (Q7VJC6)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_859848.2
- HSSP:   P10408
- ProteinModelPortal:   Q7VJC6
- SMR:   Q7VJC6
- GeneID:   1493371
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0317
- NMPDR:   fig|235279.1.peg.317
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   HHEP235279:HH_0317-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 96959; Mature: 96959

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTLISKFLGSRNNKLIKHYLKEVQAINALESTYNTLSDAQLQEAFMQLRKLIQNGETS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LQSILHKSFAITREASKRVLGMRHFDVQLIGGMALNDGRIAEMKTGEGKTLVATLAVCLN
HHHHHHHHHHHHHHHHHHHHCCHHCCEEEECCEEECCCEEEEEECCCCCHHHHHHHHHHH
ALCGRGVHVVTVNDYLANRDAKELEPLYNFLGFEVGIITSEVRDDNERLQAYACDIVYGT
HHHCCCEEEEEECHHHHCCCHHHHHHHHHHHCCHHEEEEHHHCCCHHHHHEEEEEEEECC
NNEFGFDYLRDNMKYDLSQKVQGEHYFAIIDEVDSILIDEARTPLIISGPVNRTLEHYQL
CCCCCHHHHHCCCCCCHHHHCCCCEEEEEHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
ANSVAQRLKNEEDFSIDEKNRVILLNEEGIKKAESLFKVDNLYSIENAALSHHLDQALKA
HHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NYLFIKDKDYVVQNDEVVIVDEFTGRLSEGRRFSEGLHQAIEAKEKVDIKEESQTLADIT
CEEEEECCCEEEECCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FQNYFRLYEKLSGMTGTAQTEASEFLQIYNLEVVSIPTNVPVQRKDLNDLIYKSEKEKFN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AVIDKIQELYKKGQPVLVGTASIEKSEILHELLKKHRIPHTVLNAKQHTKEAEIIKDAGV
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCC
KGAVTIATNMAGRGVDIKINDEIRELGGLYIIGTERHESRRIDNQLRGRAGRQGDPGISQ
CCEEEEEECCCCCCEEEEECHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHH
FYLSLEDSLLRIFGSDKIKGIMERLGLKEGEHIESGLVTRSVESAQKKVENLHFESRKHL
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEYDDVANEQRKAVYKLRNELLDENCSLQERISTNRELTAQSMLYKAQILPGDDSSNFNI
HHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHEECCCCCCCCCCH
DSLKAQINEELGLEIGNCENLDYDELLEKLITQMNTAYEEKMSKLEESQRAQIERIIYLQ
HHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLDSSWREHLYTMDNLKTGIGLRGYNQKDPLVEYKKESYNLFLEFVENLKFETTKMLQII
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QLRDKEEEVANKMIKNLQDELEENLQDLNTNMDSTPVRKNKIARNDPCPCGSGKKYKVCH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEC
GKSGPKSGLLA
CCCCCCCCCCC
>Mature Secondary Structure
MLQTLISKFLGSRNNKLIKHYLKEVQAINALESTYNTLSDAQLQEAFMQLRKLIQNGETS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LQSILHKSFAITREASKRVLGMRHFDVQLIGGMALNDGRIAEMKTGEGKTLVATLAVCLN
HHHHHHHHHHHHHHHHHHHHCCHHCCEEEECCEEECCCEEEEEECCCCCHHHHHHHHHHH
ALCGRGVHVVTVNDYLANRDAKELEPLYNFLGFEVGIITSEVRDDNERLQAYACDIVYGT
HHHCCCEEEEEECHHHHCCCHHHHHHHHHHHCCHHEEEEHHHCCCHHHHHEEEEEEEECC
NNEFGFDYLRDNMKYDLSQKVQGEHYFAIIDEVDSILIDEARTPLIISGPVNRTLEHYQL
CCCCCHHHHHCCCCCCHHHHCCCCEEEEEHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
ANSVAQRLKNEEDFSIDEKNRVILLNEEGIKKAESLFKVDNLYSIENAALSHHLDQALKA
HHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NYLFIKDKDYVVQNDEVVIVDEFTGRLSEGRRFSEGLHQAIEAKEKVDIKEESQTLADIT
CEEEEECCCEEEECCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FQNYFRLYEKLSGMTGTAQTEASEFLQIYNLEVVSIPTNVPVQRKDLNDLIYKSEKEKFN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AVIDKIQELYKKGQPVLVGTASIEKSEILHELLKKHRIPHTVLNAKQHTKEAEIIKDAGV
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCC
KGAVTIATNMAGRGVDIKINDEIRELGGLYIIGTERHESRRIDNQLRGRAGRQGDPGISQ
CCEEEEEECCCCCCEEEEECHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHH
FYLSLEDSLLRIFGSDKIKGIMERLGLKEGEHIESGLVTRSVESAQKKVENLHFESRKHL
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEYDDVANEQRKAVYKLRNELLDENCSLQERISTNRELTAQSMLYKAQILPGDDSSNFNI
HHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHEECCCCCCCCCCH
DSLKAQINEELGLEIGNCENLDYDELLEKLITQMNTAYEEKMSKLEESQRAQIERIIYLQ
HHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLDSSWREHLYTMDNLKTGIGLRGYNQKDPLVEYKKESYNLFLEFVENLKFETTKMLQII
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QLRDKEEEVANKMIKNLQDELEENLQDLNTNMDSTPVRKNKIARNDPCPCGSGKKYKVCH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEC
GKSGPKSGLLA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12810954